Studies on vitellogenin and its receptor in salmonid using interactome techniques
| Project/Area Number |
21780172
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
General fisheries
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| Research Institution | Hokkaido University |
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Principal Investigator |
HIRAMATSU Naoshi Hokkaido University, 大学院・水産科学研究院, 助教 (10443920)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2009: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | サケ科魚類 / 蛋白質相互作用 / ビテロジェニン / ビテロジェニン受容体 / 卵形成 / 水産学 / 魚類繁殖生理学 |
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| Research Abstract |
When fish grows ovaries, a yolk precursor vitellogenin (Vg) is incorporated from the blood into oocyte following its binding to ovarian Vg receptor (VgR). This study first identified a portion of VgR-binding region on salmon Vg (sVg) using cutting-edged interactome techniques. Further, a novel C-type Vg (VgC) was cloned and its recombinant protein was synthesized with a limited amount; this provided a basis for discovering the unrevealed VgC receptor.
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Report
(3 results)
Research Products
(13 results)
