Pathogen specific innate immune responses in fish
| Project/Area Number |
21780194
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Fisheries chemistry
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| Research Institution | Tokyo University of Marine Science and Technology |
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Principal Investigator |
KONDO Hidehiro Tokyo University of Marine Science and Technology, 海洋科学技術研究科, 准教授 (20314635)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2009: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 魚類病原微生物 / 魚類免疫学 / 自然免疫応答 / 分子生物学 / マイクロアレイ / 魚病細菌 / Edwardsiella tarda / Streptococcus iniae / Vibrio anguillarum / Lactococcus garvieae |
|---|
| Research Abstract |
Genes differently expressed in a pathogenic microorganisms specific manner were identified and the regulation mechanisms of their expression were evaluated in fish, especially for Japanese flounder. In response to bacteria, a number of immune-related genes were strongly induced by Gram-negative bacteria rather than by Gram-negative bacteria. In response to viruses, gene expression profiles were strongly influenced by rearing temperatures.
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Report
(3 results)
Research Products
(7 results)
