Studies on the chick-specific feeding-stimulatory mechanism regulated by somatostatin

• Project/Area Number: 21780247
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Zootechnical science/Grassland science
• Research Institution: Ehime University
• Principal Investigator: TACHIBANA Tetsuya 愛媛大学, 農学部, 准教授 (80346832)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2009: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
• Keywords: 栄養・飼養 / 飼養 / 畜産学 / 脳・神経 / 行動学 / 薬理学 / 栄養学

Research Abstract

The present study revealed that somatostatin in the brain stimulated feeding behavior of chicks. The orexigenic effect of somatostatin is at least partly mediated by somatostatin receptor-2,-3 and-5. In addition, the hypothalamus is related to the effect of somatostatin. It is likely that the orexigenic effect of somatostatin is related to growth hormone and prolactin, which are released from the anterior pituitary, and neuropeptide Y, another orexigenic peptide. These results will contribute to clarify the regulatory mechanism of feeding behavior in chicks.

Research Products

• [Journal Article] Feeding responses to central administration of several somatostatin analogs in chicks (2011)
  • Author(s): Tachibana T, Cline MA, Khan MS, Ueda H, Hiramatsu K.
  • Journal Title: Comp Biochem Physiol A Mol Integr Physiol Volume: 158 Pages: 47-51
  • Peer Reviewed
• [Journal Article] Feeding responses to central administration of several somatostatin analogs in chicks. (2011)
  • Author(s): Tachibana T, Cline MA, Khan MS, Ueda H, Hiramatsu K.
  • Journal Title: Comp Biochem Physiol A Mol Integr Physiol. Volume: 158 Pages: 47-51
  • Peer Reviewed
• [Journal Article] Feeding and drinking response following central administrations of bombesin-like peptides in chicks (2010)
  • Author(s): Tachibana T, Matsuda K, Khan SI, Ueda H, Cline MA
  • Journal Title: Comp Biochem Physiol A Mol Integr Physiol Volume: 156 Pages: 394-399
  • Peer Reviewed
• [Journal Article] Feeding and drinking response following central administration of neuromedin S in chicks (2010)
  • Author(s): Tachibana T, Matsuda K, Khan MS, Ueda H, Cline MA
  • Journal Title: Comp Biochem Physiol A Mol Integr Physiol Volume: 157 Pages: 63-67
  • Peer Reviewed
• [Journal Article] Feeding and drinking response following central administration of neuromedin S in chicks. (2010)
  • Author(s): Tachibana T, Matsuda K, Khan MS, Ueda H, Cline MA.
  • Journal Title: Comp Biochem Physiol A Mol Integr Physiol. Volume: 157 Pages: 63-67
  • Peer Reviewed
• [Journal Article] Feeding and drinking response following central administrations of bombesin-like peptides in chicks. (2010)
  • Author(s): Tachibana T, Matsuda K, Khan SI, Ueda H, Cline MA.
  • Journal Title: Comp Biochem Physiol A Mol Integr Physiol. Volume: 156 Pages: 394-399
  • Peer Reviewed
• [Journal Article] Feeding and drinking response following central administrations of bombesin-like peptides in chicks
  • Author(s): Tachibana T, et al.
  • Journal Title: Comparative Biochemistry and Physiology Part A (印刷中)
  • Peer Reviewed