The mechanism of severe disease development following encephalitic flavivirus infection
| Project/Area Number |
21780281
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Applied veterinary science
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| Research Institution | Nagasaki University |
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Principal Investigator |
HAYASAKA Daisuke Nagasaki University, 熱帯医学研究所, 助教 (10346926)
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| Co-Investigator(Renkei-kenkyūsha) |
NAGATA Noriyo 国立感染症研究所, 感染病理部, 研究員 (30270648)
FUJII Yoshiki 独立行政法人国立病院機構, 相模原病院, 研究員 (40518122)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2009: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | ウイルス / 人獣共通感染症 / 免疫病原性 / 脳神経疾患 / 感染症 / 獣医学 |
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| Research Abstract |
To elucidate the mechanism of severe disease following encephalitic flavivirus infection, we investigated the pathogenic mechanism following Tick-borne encephalitis virus (TBEV) and Japanese encephalitis virus (JEV) infections in a mouse model. We concluded that multiple factors of CNS infection and immunopathogenicity determine the severe form of encephalitic flavivirus infection
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Report
(3 results)
Research Products
(27 results)
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[Presentation] The mechanism of severe form of Japanese encephalitis virus infection2010
Author(s)
Daisuke Hayasaka, Yoshiki Fujii, Dihn Tuan Duc, Hitomi Kinoshita, Kazuki Kitaura, Noriyo Nagata, Naoko Iwata, Kanae Tanaka, Tetsutaro Sata, Ryuji Suzuki, Kouichi Morita
Organizer
US-Japan 44th Joint Working Conference on Viral Diseases,
Place of Presentation
札幌、北海道大学百年記念会館
Year and Date
2010-06-29
Related Report
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[Presentation] The mechanism of severe form of Japanese encephalitis virus infection2010
Author(s)
Daisuke Hayasaka, Yoshiki Fujii, Dihn Tuan Duc, Hitomi Kinoshita, Kazuki Kitaura, Noriyo Nagata, Naoko Iwata, Kanae Tanaka, Tetsutaro Sata, Ryuji Suzuki, Kouichi Morita
Organizer
US-Japan 44^<th> Joint Working Conference on Viral Diseases, Sapporo
Place of Presentation
札幌、北海道大学百年記念会館
Year and Date
2010-06-29
Related Report
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