| Project/Area Number |
21780281
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Applied veterinary science
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| Research Institution | Nagasaki University |
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Principal Investigator |
HAYASAKA Daisuke Nagasaki University, 熱帯医学研究所, 助教 (10346926)
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| Co-Investigator(Renkei-kenkyūsha) |
NAGATA Noriyo 国立感染症研究所, 感染病理部, 研究員 (30270648)
FUJII Yoshiki 独立行政法人国立病院機構, 相模原病院, 研究員 (40518122)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2009: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | ウイルス / 人獣共通感染症 / 免疫病原性 / 脳神経疾患 / 感染症 / 獣医学 |
|---|
| Research Abstract |
To elucidate the mechanism of severe disease following encephalitic flavivirus infection, we investigated the pathogenic mechanism following Tick-borne encephalitis virus (TBEV) and Japanese encephalitis virus (JEV) infections in a mouse model. We concluded that multiple factors of CNS infection and immunopathogenicity determine the severe form of encephalitic flavivirus infection
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