Study on Novel Enantiotopic Group Selective Enyne Metathesis Reaction by Chiral Ruthenium Catalyst
| Project/Area Number |
21790002
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Chemical pharmacy
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| Research Institution | Hokkaido University |
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Principal Investigator |
SAITO Nozomi Hokkaido University, 大学院・薬学研究院, 准教授 (80349258)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 有機化学 / メタセシス / エニン / ルテニウム / カルベン錯体 / 含窒素ヘテロ環カルベン / ジエンイン / 不斉環化反応 / エンジイン |
|---|
| Research Abstract |
In order to create new class of chiral building blocks, enantiotopic groupselective intramolecular ene-yne metathesis reaction using ruthenium carbene complex bearing a chiral N-heterocyclic carbene ligand was investigated. As a result, a cyclic compound having a tetra-subustituted carbon atom was produced up to 34% ee.
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Report
(3 results)
Research Products
(56 results)
