Development of efficient synthetic methods of nitrogen containing heterocycles by one-pot sequential reactions
| Project/Area Number |
21790015
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Chemical pharmacy
|
|---|
| Research Institution | Osaka University |
|---|
Principal Investigator |
MURAI Kenichi 大阪大学, 大学院・薬学研究科, 助教 (70532068)
|
|---|
| Project Period (FY) |
2009 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
|---|
| Keywords | 複素環化学 / 環境調和反応 / ワンポット反応 / アミナール / 含窒素化合物 / オキサゾール / イミダゾリン / 環境調和 / 連続反応 / 多成分反応 / 環境対応 |
|---|
| Research Abstract |
We studied for the development of efficient synthetic methods of nitrogen containing heterocycles and obtained the following results: 1) the efficient synthetic methods for amide substituted imidazolines and benzimidazoles at 2-posittion was developed. 2) the novel synthetic method for oxazoles was developed. 3) a tandem reaction providing ・-(N-indolyl)-・,・-unsaturated esters from ・-keto esters and o-alkynyl anilines was developed.
|
Report
(3 results)
Research Products
(49 results)
