Development of glucose-sensitive Insulin Release System with Molecular Imprinting

• Project/Area Number: 21790040
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Physical pharmacy
• Research Institution: Ohu University
• Principal Investigator: ONO Tetsuya Ohu University, 薬学部, 助手 (70433555)
• Project Period (FY): 2009 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000); Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2009: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
• Keywords: 物理化学 / 糖尿病 / 分子認識

Research Abstract

It is possible to produce the polymers that have plural functions with electrochemical polymerization. The properties of the polymers can be modulated by varying the applied polymerization potential. These results suggest that the controlled release system can be achieved with no operation from the outside.

Research Products

• [Journal Article] Voltammetric Behavior of Mediator Modified Electrode by Electrochemical Polymerization of Nitroxyl Radical Precursor Containing Pyrrole Side Chain (2010)
  • Author(s): Tetsuya Ono, Makiko Tsunoda, Shigehiro Takahashi, Toshio Obata, Takanori Sone, Yoshitomo Kashiwagi
  • Journal Title: Heterocycles Vol.81, No.12 Pages: 2771-2780
  • NAID: 40017375387
  • Peer Reviewed
• [Journal Article] Voltammetric Behavior of Mediator-Modified Electrode by Electrochemical Polymerization of Nitroxyl Radical Precursor Containing Pyrrole Side Chain (2010)
  • Author(s): Tetsuya Ono
  • Journal Title: HETEROCYCLES Volume: 81 Pages: 2771-2780
  • NAID: 40017375387
  • Peer Reviewed
• [Presentation] 電解重合法により作製したニトロキシルラジカル置換ピロール固定化電極を用いたアミン類の電解触媒酸化反応 (2010)
  • Author(s): 小野哲也、高森由美子、曽根孝範、柏木良友
  • Organizer: 第40回複素環化学討論会
  • Place of Presentation: 仙台市民会館
  • Year and Date: 2010-10-14
• [Presentation] 電解重合法により作製したニトロキシルラジカル置換ピロール固定化電極を用いたアミン類の電解触媒酸化反応 (2010)
  • Author(s): 小野哲也
  • Organizer: 第40回複素環化学討論会
  • Place of Presentation: 仙台市民会館(宮城県)
  • Year and Date: 2010-10-14
• [Presentation] 電解重合法により作製したニトロキシルラジカル置換ピロール固定化電極の電極反応挙動 (2010)
  • Author(s): 小野哲也
  • Organizer: 日本薬学会第130年会
  • Place of Presentation: 岡山桃太郎アリーナ
  • Year and Date: 2010-03-29