| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Research Abstract |
We have proposed a novel method for development of drugs using invertebrate pathogenic animal model. In this study, we established hyperglycemic model in silkworm and identified galactose as a hypoglycemic drug from herbal medicine, jiou, by monitoring hypoglycemic activity in the hyperglycemic silkworm model. Moreover, we also developed diabetic complication model in silkworm. This is a first report to identify anti-diabetic compound using invertebrate hypoglycemic model.
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