Roles of the minor sialic acid molecular species in hippocampal dependent memory
| Project/Area Number |
21790085
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Biological pharmacy
|
|---|
| Research Institution | University of Shizuoka |
|---|
Principal Investigator |
AKIRA Minami 静岡県立大学, 薬学部・生化学教室, 助教 (80438192)
|
|---|
| Project Period (FY) |
2009 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
|---|
| Keywords | 糖鎖 / 記憶 / 海馬 / 神経 / シアル酸分子種 / シアリダーゼ / インビボ解析 / 酵素活性イメージング / シアル酸 / 電気生理 / インビボ / ラット |
|---|
| Research Abstract |
N-Acetylneuraminic acid(Neu5Ac), the major molecular species of sialic acid, is contained in mammalian brain abundantly and plays crucial roles in many neural functions including memory. However, roles of other minor molecular species of sialic acid were poorly understood. In this project, we found the roles of the minor sialic acid molecular species in hippocampal dependent memory.
|
Report
(4 results)
Research Products
(34 results)
-
[Journal Article] Imaging of sialidase activity in rat brain sections by a highly sensitive fluorescent histochemical method2011
Author(s)
Minami, A., Shimizu, H., Meguro, Y., Shibata, N., Kanazawa, H., Ikeda, K., and Suzuki, T
-
Journal Title
NeuroImage
Volume: 58
Issue: 1
Pages: 34-40
DOI
Related Report
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
