Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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Research Abstract |
GPR55 is a putative novel cannabinoid receptor and its endogenous ligand is lysophosphatidylinositol (LPI). This study revealed that LPI plays some essential roles in the regulation of cytoskeletal functions and stress responses. Furthermore, we searched for the ligand for GPR35 which has 30% homology with GPR55, and found that 2-acyl lysophosphatidic acid (LPA) may act as an endogenous ligand for GPR35.
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