| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2009: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Research Abstract |
Cell-penetrating peptides (CPPs) have been used as carriers to efficiently deliver various types of molecules that are difficult to internalize into cells by themselves. In this research, to examine cell-specific delivery using functional CPPs bearing specific-molecule target sequences was conducted. Using leucine zipper peptides, we ascertained cell-specific internalization of CPP through target-sequence expressed cell membranes with less cytotoxicity.
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