| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Research Abstract |
The kidney is the most important organ for the drug excretion. In the proximal tubules, drug transporters play the important roles for renal drug secretion. In this study, changes of renal drug transporters under renal diseases and correlation of regulator factors for renal diseases with drug transporter expression. The authors found that organic anion transporter decreased under acidosis condition and then that anionic drug secretion was decreased.
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