| Project/Area Number |
21790175
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
General anatomy (including Histology/Embryology)
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| Research Institution | Gunma University |
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Principal Investigator |
TAJIKA Yuki 群馬大学, 大学院・医学系研究科, 助教 (90400738)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | 骨格筋 / 小胞輸送 / 骨格筋細胞 / 膜輸送 / SNARE / 筋分化 / 抗体染色 / 顕微鏡 |
|---|
| Research Abstract |
Membrane trafficking is a fundamental event for the life of cell. Previous studies using neuron and epithelial cells revealed its molecular mechanism, including SNARE proteins, which regulate membrane tethering and fusion process. VAMP5, a member of SNARE proteins, was found in transcripts from skeletal muscle, however, the protein levels in a whole body was not known. In this study, we performed immunostaining on skeletal muscle and other tissues, and clarified the expression pattern of VAMP5.
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