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Role of SCGB3A2 in pulmonary fibrosis

Research Project

Project/Area Number 21790207
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field General physiology
Research InstitutionYamagata University (2010-2011)
Yokohama City University (2009)

Principal Investigator

KUROTANI Reiko  山形大学, 大学院・理工学研究科, 助教 (00453043)

Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
KeywordsSCGB3A2 / 肺線維症 / STAT1 / SMAD7 / サーファクタント
Research Abstract

An explosive number of people are affected by fibrosis worldwide in these days, and the morbidity and mortality rates are increasing every year. The exploration and/or development of a definitive medicine are urgently required. We report that SCGB3A2 drastically reduces the severity of lung fibrosis using bleomycin (BLM)-induced mouse model. Mice were intravenously administered SCGB3A2 for 7 days starting at day 14 after administration of BLM by intratracheal intubation. Fibrosis foci were remarkably reduced by SCGB3A2 in lung lobes and the number of neutrophils and macrophages was also reduced in branchoalveolar lavage fluid (BALF). Additionally, when lung fibroblast cells isolated from adult mice were differentiated into myofibroblast cells by TGFβ, the differentiation was inhibited by SCGB3A2 as judged by morphology and reduced expression of a smooth muscle actin (αSMA). Collagen 1a2 and 3a1 gene expression was also decreased in the presence of SCGB3A2.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (62 results)

All 2012 2011 2010 2009 Other

All Journal Article (20 results) (of which Peer Reviewed: 16 results) Presentation (37 results) Remarks (5 results)

  • [Journal Article] Secretoglobin 3A2 suppresses bleomycin-induced pulmonary fibrosis by TGFbeta signaling down-regulation2011

    • Author(s)
      Kurotani R, Okumura S, Matsubara T, Yokoyama U, Buckley JR, Tomita T, Kezuka K, Nagano T, Esposito D, Taylor TE, Gillette WK, Ishikawa Y, Abe H, Ward JM, Kimura S
    • Journal Title

      J Biol Chem

      Volume: 286(22) Pages: 19682-19692

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Ishikawa Y, Identification of transcription factor E3 (TFE3) as a receptor-independent activator of G{alpha}16 : Gene regulation by nuclear G{alpha} subunit and its activator2011

    • Author(s)
      Sato M, Hiraoka M, Suzuki H, Bai Y, Kurotani R, Yokoyama U, Okumura S, Cismowski MJ, Lanier SM
    • Journal Title

      J Biol Chem

      Volume: 286(20) Pages: 17766-17776

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Secretoglobin 3A2/uteroglobin-related protein 1 is a novel marker for pulmonary carcinoma in mice and humans2011

    • Author(s)
      Kurotani R, Kumaki N, Linnoila RI, Ward JM, Kimura S
    • Journal Title

      Lung Cancer 2011

      Volume: 71(1) Pages: 42-48

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Secretoglobin 3A2 suppresses bleomycin-induced pulmonary fibrosis by TGFbeta signaling down-regulation2011

    • Author(s)
      Kurotani R, Okumura S, Matsubara T, Yokoyama U, Buckley JR, Tomita T, Kezuka K, Nagano T, Esposito D, Taylor TE, Gillette WK, Ishikawa Y Abe H, Ward JM, Kimura S
    • Journal Title

      J Biol Chem.

      Volume: 286 Pages: 19682-19692

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Secretoglobin 3A2/uteroglobin-related protein 1 is a novel marker for pulmonary carcinoma in mice and humans2011

    • Author(s)
      Kurotani R, Kumaki N, Linnoila RI, Ward JM, Kimura S
    • Journal Title

      Lung Cancer

      Volume: 71 Pages: 42-48

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Identification of transcription factor E3 (TFE3) as a receptor-independent activator of G{alpha}16 : Gene regulation by nuclear G{alpha} subunit and its activator2011

    • Author(s)
      Sato M, Hiraoka M, Suzuki H, Bai Y, Kurotani R, Yokoyama U, Okumura S, Cismowski MJ, Lanier SM, Ishikawa Y
    • Journal Title

      J Biol Chem

      Volume: 286 Pages: 17766-17776

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Differential roles of EPAC in regulating cell death in neuronal and myocardial cells2010

    • Author(s)
      Suzuki S, Yokoyama U, Abe T, Kiyonari H, Yamashita N, Kato Y, Kurotani R, Sato M, Okumura S, Ishikawa Y
    • Journal Title

      J Biol Chem

      Volume: 285(31)

    • Related Report
      2011 Final Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Differential Regulation of Vascular Tone and Remodeling via Stimulation of Type 2 and Type 6 Adenylyl Cyclases in the Ductus Arteriosus2010

    • Author(s)
      Yokoyama U, Minamisawa S, Katayama A, Tang T, Suzuki S, Iwatsubo K, Iwasaki S, Kurotani R, Okumura S, Sato M, Yokota S, Hammond HK, Ishikawa Y
    • Journal Title

      Circ Res

      Volume: 106(12) Pages: 1882-1892

    • Related Report
      2011 Final Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 磁性体を利用した薬剤送達法2010

    • Author(s)
      黒谷玲子, 福村英信, 佐藤格, 江口晴樹, 石川義弘
    • Journal Title

      磁気と健康

      Volume: 23号 Pages: 10-13

    • Related Report
      2011 Final Research Report
  • [Journal Article] Caveolin gene transfer improves glucose metabolism in diabetic mice2010

    • Author(s)
      Otsu K, Toya Y, Oshikawa J, Kurotani R, Yazawa T, Sato M, Yokoyama U, Umemura S, Minamisawa S, Okumura S, Ishikawa Y
    • Journal Title

      Am J Physiol Cell Physiol

      Volume: 298(3)

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] 磁性体を利用した薬剤送達法2010

    • Author(s)
      黒谷玲子、福村英信、佐藤格、江口晴樹、石川義弘
    • Journal Title

      磁気と健康

      Volume: 23 Pages: 10-13

    • Related Report
      2010 Annual Research Report
  • [Journal Article] Caveolin gene transfer improves glucose metabolism in diabetic mice.2010

    • Author(s)
      Otsu K, Toya Y, Oshikawa J, Kurotani R, Yazawa T, Sato M, Yokoyama U, Umemura S, Minamisawa S, Okumura S, Ishikawa Y
    • Journal Title

      Am J Physiol Cell Physiol. 298

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Activator of G protein signaling 8 (AGS8) is required for hypoxia-induced apoptosis of cardiomyocytes : Role of gbetagamma and connexin43 (CX43)2009

    • Author(s)
      Sato M, Jiao Q, Honda T, Kurotani R, Toyota E, Okumura S, Takeya T, Minamisawa S, Lanier SM, Ishikawa Y
    • Journal Title

      J Biol Chem

      Volume: 284(45) Pages: 31431-31440

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Drug Delivery System Using Magnetic Materials2009

    • Author(s)
      Shimada C, Kurotani R, U Fukumura H, Ono S, Egushi H, Ishikawa Y
    • Journal Title

      日本病態生理学会雑誌

      Volume: 第18巻第1号 Pages: 24-27

    • Related Report
      2011 Final Research Report
  • [Journal Article] Epac Increases Melanoma Migration by a Heparan Sulfate-Related Mechanism2009

    • Author(s)
      Baljinnyam E, Iwatsubo K, Kurotani R, Wang X, Ulucan C, Iwatsubo M, Lagunoff D, Ishikawa Y
    • Journal Title

      Am J Physiol Cell Physiol

      Volume: 297(4)

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] HING2 is upregulated in colon cancer and increases invasion by enhanced MMP13 expression2009

    • Author(s)
      Kumamoto K, Fujita K, UKurotani RU, Saito M, Unoki M, Hagiwara N, Shiga H, Bowman ED, Yanaihara N, Okamura S, Nagashima M, Miyamoto K, Takenoshita S, Yokota J, Harris CC
    • Journal Title

      Int J Cancer

      Volume: 125(6) Pages: 1306-1315

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] ING2 is upregulated in colon cancer and increases invasion by enhanced MMP13 expression.2009

    • Author(s)
      Kumamoto K, Fujita K, Kurotani R, Saito M, Unoki M, Hagiwara N, Shiga H, Bowman ED, Yanaihara N, Okamura S, Nagashima M, Miyamoto K, Takenoshita S, Yokota J, Harris CC.
    • Journal Title

      Int J Cancer. 125

      Pages: 1306-1315

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Epac Increases Melanoma Migration by a Heparan Sulfate-Related Mechanism.2009

    • Author(s)
      Baljinnyam E^*, Iwatsubo K^*(^*c ontribution equally), Kurotani R, Wang X, Ulucan C, Iwatsubo M, Lagunoff D, Ishikawa Y.
    • Journal Title

      Am J Physiol Cell Physiol. 297

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Drug Delivery System Using Magnetic Materials2009

    • Author(s)
      ShimadaC, Kurotani R, Fukumura H, Ono S, Egushi H, Ishikawa Y.
    • Journal Title

      日本病態生理学会雑誌 18

      Pages: 24-27

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Activator of G protein signaling 8 (AGS8) is required for hypoxia-in duced apoptosis of cardiomyocytes : Role of gbetagamma and connexin43 (CX43).2009

    • Author(s)
      Sato M, Jiao Q, Honda T, Kurotani R, Toyota E, Okumura S, Takeya T, Minamisawa S, Lanier SM, Ishikawa Y.
    • Journal Title

      J Biol Chem. 284

      Pages: 31431-31440

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] マウス初期胚におけるミトコンドリア呼吸機能の階層的解析Hierarchical analysis of mitochondrial respiration activity in mouse embryos2012

    • Author(s)
      渡邉剛広、島麗香、高倉啓、黒谷玲子、阿部宏之
    • Organizer
      第27回東日本ET研究会
    • Place of Presentation
      飛騨高山
    • Related Report
      2011 Annual Research Report
  • [Presentation] ウシ初期胚におけるミトコンドリア呼吸機能解析:シトクロムcオキシダーゼ遺伝子発現解析の試みRespiration activity of bovine embryos : attempts to detect cytochrome c oxidase gene expression2012

    • Author(s)
      海藤康平、高倉啓、黒谷玲子、阿部宏之
    • Organizer
      第27回東日本ET研究会
    • Place of Presentation
      飛騨高山
    • Related Report
      2011 Annual Research Report
  • [Presentation] 異なる温度条件下で保存したウシ卵巣における組織学的変化Histological analysis of bovine ovaries stored for long time at distinct temperatures2012

    • Author(s)
      萩本範幸、高倉啓、黒谷玲子、阿部靖之、阿部宏之
    • Organizer
      第27回東日本ET研究会
    • Place of Presentation
      飛騨高山
    • Related Report
      2011 Annual Research Report
  • [Presentation] Symposium "Low Invasive Diagnosis and Therapy Using Magnetics" Development of cancer therapies using a novel magnetic material2011

    • Author(s)
      Reiko Kurotani
    • Organizer
      第35回 日本磁気学会学術講演会
    • Place of Presentation
      新潟(朱鷺メッセ)(招待講演)
    • Year and Date
      2011-09-28
    • Related Report
      2011 Annual Research Report
  • [Presentation] 電気化学計測技術を応用した単一培養細胞の呼吸能解析2011

    • Author(s)
      高倉啓, 黒谷玲子, 阿部宏之
    • Organizer
      日本機械学会東北支部第47期秋期講演会
    • Place of Presentation
      米沢市、山形大学
    • Year and Date
      2011-09-22
    • Related Report
      2011 Final Research Report
  • [Presentation] リアルタイム培養細胞観察システムを用いたマウス胚発生のタイムラプス解析2011

    • Author(s)
      栢本亮太, 長畑仁美, 大江将司, 阿部靖之, 黒谷玲子, 阿部宏之
    • Organizer
      日本機械学会東北支部第47期秋期講演会
    • Place of Presentation
      米沢市、山形大学
    • Year and Date
      2011-09-22
    • Related Report
      2011 Final Research Report
  • [Presentation] リアルタイム培養細胞観察システムを用いたマウス胚発生のタイムラプス解析2011

    • Author(s)
      栢本亮太、長畑仁美、大江将司、阿部靖之、黒谷玲子、阿部宏之
    • Organizer
      日本機械学会東北支部第47期秋期講演会
    • Place of Presentation
      米沢市、山形大学工学部
    • Year and Date
      2011-09-22
    • Related Report
      2011 Annual Research Report
  • [Presentation] 電気化学計測技術を応用した単一培養細胞の呼吸能解析2011

    • Author(s)
      高倉啓、黒谷玲子、阿部宏之
    • Organizer
      日本機械学会東北支部第47期秋期講演会
    • Place of Presentation
      米沢市、山形大学工学部
    • Year and Date
      2011-09-22
    • Related Report
      2011 Annual Research Report
  • [Presentation] マウス胚におけるミトコンドリア呼吸機能の多項目解析の試み2011

    • Author(s)
      渡邉剛広, 黒谷玲子, 阿部宏之
    • Organizer
      日本動物学会平成23年度東北支部大会
    • Place of Presentation
      弘前市、弘前大学
    • Year and Date
      2011-07-30
    • Related Report
      2011 Final Research Report
  • [Presentation] SCGB3A2はTGFβシグナルの制御によってブレオマイシン誘導性肺線維症を抑制する2011

    • Author(s)
      黒谷玲子, 木村芝生子, 阿部宏之
    • Organizer
      日本動物学会平成23年度東北支部大会
    • Place of Presentation
      弘前市、弘前大学
    • Year and Date
      2011-07-30
    • Related Report
      2011 Final Research Report
  • [Presentation] 電気化学計測法を応用した単一培養細胞の呼吸能解析の試み2011

    • Author(s)
      阿部宏之, 高倉啓, 黒谷玲子
    • Organizer
      日本動物学会平成23年度東北支部大会
    • Place of Presentation
      弘前市、弘前大学
    • Year and Date
      2011-07-30
    • Related Report
      2011 Final Research Report
  • [Presentation] 電気化学計測法を応用した単一培養細胞の呼吸能解析の試み2011

    • Author(s)
      阿部宏之、高倉啓、黒谷玲子
    • Organizer
      日本動物学会平成23年度東北支部大会
    • Place of Presentation
      弘前市、弘前大学農学生命科学部
    • Year and Date
      2011-07-30
    • Related Report
      2011 Annual Research Report
  • [Presentation] SCGB3A2はTGFβシグナルの制御によってブレオマイシン誘導性肺線維症を抑制する2011

    • Author(s)
      黒谷玲子、木村芝生子、阿部宏之
    • Organizer
      日本動物学会平成23年度東北支部大会
    • Place of Presentation
      弘前市、弘前大学農学生命科学部
    • Year and Date
      2011-07-30
    • Related Report
      2011 Annual Research Report
  • [Presentation] マウス胚におけるミトコンドリア呼吸機能の多項目解析の試み2011

    • Author(s)
      渡邉剛広、黒谷玲子、阿部宏之
    • Organizer
      日本動物学会平成23年度東北支部大会
    • Place of Presentation
      弘前市、弘前大学農学生命科学部
    • Year and Date
      2011-07-30
    • Related Report
      2011 Annual Research Report
  • [Presentation] マウス肺発生におけるシトクロムc酸化酵素(Cox)の発現2011

    • Author(s)
      黒谷玲子, 佐々木昭美, 小川拓, 阿部宏之
    • Organizer
      第52回日本組織細胞化学会総会・学術集会
    • Place of Presentation
      金沢市、金沢大学
    • Related Report
      2011 Final Research Report
  • [Presentation] 喫煙マウス肺におけるサーファクタントとシトクロムc酸化酵素(Cox)の発現2011

    • Author(s)
      小簑清香, 熊木伸枝, 佐々木昭美, 小川拓, 阿部宏之, 柴田陽光, 黒谷玲子
    • Organizer
      第52回日本組織細胞化学会総会・学術集会
    • Place of Presentation
      金沢市、金沢大学
    • Related Report
      2011 Final Research Report
  • [Presentation] マウス初期胚におけるミトコンドリア呼吸機能の多項目解析2011

    • Author(s)
      阿部宏之, 小川拓, 渡邊剛広, 黒谷玲子
    • Organizer
      第104回日本繁殖生物学会大会
    • Place of Presentation
      盛岡市、岩手県民情報交流センター
    • Related Report
      2011 Final Research Report
  • [Presentation] 長期保存されたウシ卵巣におけるアポトーシス細胞の組織学的検出2011

    • Author(s)
      角田夢人, 小川拓, 阿部靖之, 黒谷玲子, 阿部宏之
    • Organizer
      第26回東日本家畜受精卵移植技術研究会大会
    • Place of Presentation
      盛岡市、盛岡市民文化ホール
    • Related Report
      2011 Final Research Report
  • [Presentation] マウス初期胚におけるミトコンドリア呼吸機能の多項目解析2011

    • Author(s)
      阿部宏之、小川拓、渡邊剛広、黒谷玲子
    • Organizer
      第104回日本繁殖生物学会大会
    • Place of Presentation
      盛岡市、いわて県民情報交流センター
    • Related Report
      2011 Annual Research Report
  • [Presentation] 喫煙マウス肺におけるサーファクタントとシトクロムc酸化酵素(Cox)の発現2011

    • Author(s)
      小簑清香、熊木伸枝、佐々木昭美、小川拓、阿部宏之、柴田陽光、黒谷玲子
    • Organizer
      第52回日本組織細胞化学会総会・学術集会
    • Place of Presentation
      金沢市、金沢大学宝町キャンパス
    • Related Report
      2011 Annual Research Report
  • [Presentation] マウス肺発生におけるシトクロムc酸化酵素(Cox)の発現2011

    • Author(s)
      黒谷玲子、佐々木昭美、小川拓、阿部宏之
    • Organizer
      第52回日本組織細胞化学会総会・学術集会
    • Place of Presentation
      金沢市、金沢大学宝町キャンパス
    • Related Report
      2011 Annual Research Report
  • [Presentation] 長期保存されたウシ卵巣におけるアポトーシス細胞の組織学的検出2011

    • Author(s)
      角田夢人、小川拓、阿部靖之、黒谷玲子、阿部宏之
    • Organizer
      第26回東日本家畜受精卵移植技術研究会大会第
    • Place of Presentation
      盛岡市民文化ホール、盛岡市
    • Related Report
      2010 Annual Research Report
  • [Presentation] Controlled Drug Delivery System Using a Novel Magnetic Material2010

    • Author(s)
      Kurotani R, Fukumura H, Sato I, Kamide T, Kawamata F, Kezuka K, Eguchi H, Ishikawa Y
    • Organizer
      第33回日本分子生物学会、第83回日本生化学会合同大会
    • Place of Presentation
      神戸、神戸国際展示場
    • Year and Date
      2010-12-09
    • Related Report
      2011 Final Research Report
  • [Presentation] Controlled Drug Delivery System Using a Novel Magnetic Material2010

    • Author(s)
      Kurotani R, Fukumura H, Sato I, Kamide T, Kawamata F, Kezuka K, Eguchi H, Ishikawa Y
    • Organizer
      第33回日本分子生物学会第83回日本生化学会合同大会BMB 2010 BIOCHEMISTRY AND MOLECULAR BIOLOGY
    • Place of Presentation
      神戸ポートアイランド、神戸
    • Year and Date
      2010-12-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] 転写因子NKX2-1の下流因子として同定されたSCGB3A2の下垂体における役割2010

    • Author(s)
      黒谷玲子, 木村芝生子
    • Organizer
      日本下垂体研究会、第25回学術集会
    • Place of Presentation
      愛知、田原市、伊良湖ガーデンホテルリゾート & スパ
    • Year and Date
      2010-08-20
    • Related Report
      2011 Final Research Report
  • [Presentation] 転写因子NKX2-1の下流因子として同定されたSCGB3A2の下垂体における役割2010

    • Author(s)
      黒谷玲子、木村芝生子
    • Organizer
      日本下垂体研究会第25回学術集会
    • Place of Presentation
      伊良湖ガーデンホテル、愛知
    • Year and Date
      2010-08-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] 日本生体医工学会オーガナイズドセッション「ナノテクノロジーと物理エネルギーを融合したハイブリット標的化診断・治療」;Controlled Drug Delivery System Using a Novel Magnetic Material2010

    • Author(s)
      黒谷玲子
    • Organizer
      第49回日本生体医工学会
    • Place of Presentation
      大阪国際交流センター、大阪(招待講演)
    • Year and Date
      2010-06-26
    • Related Report
      2010 Annual Research Report
  • [Presentation] Development of simultaneous hyperthermo-chemotherapy using a drug with novel magnetic properties2010

    • Author(s)
      Fukumura H, Kurotani R, Sato I, Eguchi H, Saito T, Ishikawa Y
    • Organizer
      第33回日本分子生物学会年会、第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸、神戸国際展示場
    • Related Report
      2011 Final Research Report
  • [Presentation] 磁性体粒子を用いた新しい温熱化学療法の開発2010

    • Author(s)
      福村英信, 高橋晃, 黒谷玲子, 石川義弘, 齋藤知行
    • Organizer
      第43回日本骨軟部腫瘍学会
    • Place of Presentation
      東京、新宿区、京王プラザホテル
    • Related Report
      2011 Final Research Report
  • [Presentation] 磁性体粒子を用いた新しい温熱化学療法の開発2010

    • Author(s)
      福村英信、高橋晃、黒谷玲子、石川義弘、齋藤知行
    • Organizer
      第43回日本骨軟部腫瘍学会
    • Place of Presentation
      京王プラザホテル、東京
    • Related Report
      2010 Annual Research Report
  • [Presentation] Development of simultaneous hyperthermo-chemotherapy using a drug with novel magnetic properties2010

    • Author(s)
      Fukumura H, Kurotani R, Sato I, Eguchi H, Saito T, Ishikawa Y
    • Organizer
      第33回日本分子生物学会第83回日本生化学会合同大会BMB 2010 BIOCHEMISTRY AND MOLECULAR BIOLOGY
    • Place of Presentation
      神戸ポートアイランド、神戸
    • Related Report
      2010 Annual Research Report
  • [Presentation] SCGB3A2 reduces the severity of bleomycin-induced lung fibrosis.2009

    • Author(s)
      黒谷玲子、毛塚恭平、木村芝生子
    • Organizer
      第32回日本分子生物学会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-10
    • Related Report
      2009 Annual Research Report
  • [Presentation] 新規磁性化合物(EI236)による抗癌剤のドラッグデリバリーシステムの開発2009

    • Author(s)
      黒谷玲子, 福村英信, 石川義弘, 江口晴樹
    • Organizer
      第121回日本薬理学会関東部会
    • Place of Presentation
      東京、新宿区、東京女子医大
    • Year and Date
      2009-10-10
    • Related Report
      2011 Final Research Report
  • [Presentation] Requirement of receptor-independent G-protein activator, activator of G protein signaling 8 for hypoxia-induced apoptosis of cardiomyocytes.2009

    • Author(s)
      Sato M, Honda T, Jiao Q, Kurotani R, Toyota E, Lanier S M, Ishikawa Y.
    • Organizer
      Proceedigs of the XXXVI International Congress of Physiological Sciences (IUPS2009)
    • Place of Presentation
      京都
    • Year and Date
      2009-07-28
    • Related Report
      2009 Annual Research Report
  • [Presentation] 新規磁性薬剤化合物の画像診断への応用内閣府共催総合科学技術会議2009

    • Author(s)
      黒谷玲子, 石川義弘
    • Organizer
      科学技術連携施策群ナノバイオテクノロジー連携群成果報告会
    • Place of Presentation
      東京、江東区、日本科学未来館
    • Year and Date
      2009-01-28
    • Related Report
      2011 Final Research Report
  • [Presentation] 新規磁性化合物を利用した抗癌剤のドラッグデリバリーシステムの開発2009

    • Author(s)
      島田千恵美, 黒谷玲子, 福村英信, 小野伸二, 江口晴樹, 石川義弘
    • Organizer
      第19回日本病態生理学会
    • Place of Presentation
      埼玉、所沢市、所沢市民文化センター
    • Year and Date
      2009-01-24
    • Related Report
      2011 Final Research Report
  • [Presentation] Requirement of receptor-independent G-protein activator, activator of G protein signaling 8 for hypoxia-induced apoptosis of cardiomyocytes2009

    • Author(s)
      Motohiko Sato, Takashi Honda, Qibin Jiao, Reiko Kurotani, Eiji Toyota, Stephen M Lanier, Yoshihiro Ishikawa
    • Organizer
      Proceedigs of the XXXVI International Congress of Physiological Sciences (IUPS2009) The Journal of Physiological Sciences
    • Place of Presentation
      京都市、国立京都国際会館
    • Related Report
      2011 Final Research Report
  • [Remarks]

    • URL

      http://kurotani-lab.yz.yamagata-u.ac.jp/

    • Related Report
      2011 Final Research Report
  • [Remarks]

    • Related Report
      2011 Final Research Report
  • [Remarks]

    • URL

      http://kurotani-lab.yz.yamagata-u.ac.jp/

    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://yudb.kj.yamagata-u.ac.jp/OUTSIDE?ISTActId=SCHKOB0010RIni001&userId=100000406&lang_kbn=0

    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://www-user.yokohama-cu.ac.jp/~seiril/index.html

    • Related Report
      2009 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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