| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Research Abstract |
To search for new anti-tumor compounds, we screened new compounds for p53 dependent cell death. As a result of screenings, we identified ellagitannins from the plant extracta and 5 new natural products from the microbial metabolite. Geraniin and eugeniin, a member of ellagitannins, suppressed tumor growth of osteosarcoma cells in a xenograft model.
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