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An examination of entrainment mechanisms of the peripheral clock

Research Project

Project/Area Number 21790230
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Environmental physiology (including Physical medicine and Nutritional physiology)
Research InstitutionKinki University

Principal Investigator

SUJINO Mitsugu  Kinki University, 医学部, 助教 (30460843)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Keywords生物時計 / 体内時計 / 概日リズム / 末梢時計
Research Abstract

To elucidate the entrainment mechanisms of the peripheral clock, we carried out a series of experiments using the glucocorticoid injection and restricted feeding with a relationship of a reverse phase mutually. The results indicated the differences of the dominant timing factor among kinds of organs. The peripheral clock of the kidney and lung entrained to the time of corticosterone administration. In contrast, the liver clock was synchronized to the time of feeding.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (4 results)

All 2010 2009

All Presentation (4 results)

  • [Presentation] グルココルチコイド刺激による肝腎末梢時計の位相変化の違い2010

    • Author(s)
      筋野貢
    • Organizer
      日本時間生物学会学術大会
    • Place of Presentation
      早稲田大学国際会議場(東京)
    • Year and Date
      2010-11-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] グルココルチコイド刺激による肝腎末梢時計の位相変化の違い2010

    • Author(s)
      筋野貢、古河恵一、鯉沼聡、藤岡厚子、長野護、飯郷雅之、重吉康史
    • Organizer
      第17回日本時間生物学会学術大会
    • Place of Presentation
      東京・早稲田大学国際会議場
    • Related Report
      2010 Final Research Report
  • [Presentation] 腎臓の末梢時計におけるグルココルチコイドの影響2009

    • Author(s)
      筋野貢
    • Organizer
      日本時間生物学会
    • Place of Presentation
      大阪国際会議場(大阪府)
    • Year and Date
      2009-10-28
    • Related Report
      2009 Annual Research Report
  • [Presentation] 腎臓の時計遺伝子発現にたいするグルココルチコイドの影響2009

    • Author(s)
      筋野貢、古河恵一、鯉沼聡、藤岡厚子、長野護、飯郷雅之、重吉康史
    • Organizer
      第16回日本時間生物学会学術大会
    • Place of Presentation
      大阪・大阪国際会議場
    • Related Report
      2010 Final Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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