An examination of entrainment mechanisms of the peripheral clock
| Project/Area Number |
21790230
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Environmental physiology (including Physical medicine and Nutritional physiology)
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| Research Institution | Kinki University |
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Principal Investigator |
SUJINO Mitsugu Kinki University, 医学部, 助教 (30460843)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
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| Keywords | 生物時計 / 体内時計 / 概日リズム / 末梢時計 |
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| Research Abstract |
To elucidate the entrainment mechanisms of the peripheral clock, we carried out a series of experiments using the glucocorticoid injection and restricted feeding with a relationship of a reverse phase mutually. The results indicated the differences of the dominant timing factor among kinds of organs. The peripheral clock of the kidney and lung entrained to the time of corticosterone administration. In contrast, the liver clock was synchronized to the time of feeding.
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Report
(3 results)
Research Products
(4 results)
