| Project/Area Number |
21790254
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
General pharmacology
|
|---|
| Research Institution | Hyogo College of Medicine |
|---|
Principal Investigator |
KITANAKA Nobue Hyogo College of Medicine, 医学部, 講師 (30340954)
|
|---|
| Project Period (FY) |
2009 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
|
|---|
| Keywords | 薬物治療 / トキシコロジー / メタンフェタミン / 豊かな環境 / 依存治療 / 回転皿 / 孤独 / 不安行動 / ADHD / 覚せい剤 / 摂食行動 / 自発運動量 / 飲水行動 / ストレス |
|---|
| Research Abstract |
We investigated whether environmental enrichment (i.e. exposure to a running wheel) affected methamphetamine (METH) effects, such as hyperlocomotion and abuse, in mice. Gradually increasing running wheel activity was observed over three consecutive days after exposure to a running wheel with no effects on their food or water intakes. Exposure to the running wheel did not affect METH-induced hyperlocomotion or development of abuse, but the exposure accelerated the extinction of METH abuse.
|
