| Project/Area Number |
21790276
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
General medical chemistry
|
|---|
| Research Institution | Kobe University |
|---|
Principal Investigator |
IJUIN Takeshi 神戸大学, 大学院・医学研究科, 助教 (00361626)
|
|---|
| Project Period (FY) |
2009 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
|---|
| Keywords | 基礎医学 / SKIP / インスリン / 骨格筋 / 糖代謝 / PIP3 / グルコース / シャペロン分子 |
|---|
| Research Abstract |
Insulin stimulates glucose uptake into skeletal muscle cells. Decreased insulin sensitivity caused hyperglycemia, which increases the risk for Type II diabetes and atherosclerosis. In this study, I have shown that the PIP3 phosphatase, SKIP, modulated insulin sensitivities in the skeletal muscle.
|
