Biomarker Analysis from Human Age-Related Macular Degeneration using Imaging Mass Spectrometry
| Project/Area Number |
21790315
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Pathological medical chemistry
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| Research Institution | Hamamatsu University School of Medicine |
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Principal Investigator |
HAYASAKA Takahiro Hamamatsu University School of Medicine, 分子イメージング先端研究センター, 特任助教 (90415927)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2009: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 網膜 / 加齢黄斑変性症 / 質量分析 / イメージング / バイオマーカー / 綱膜 |
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| Research Abstract |
In this study we tried to detect biomarkers of human age-related macular degeneration (ARMD) using imaging mass spectrometry (IMS). The optimization of conventional matrices onto the surface of biological section and the application of metal core nanoparticles as a matrix enabled us to detect several lipids and fatty acids by IMS analysis. We revealed the specific biomarker from ARMD compared with normal tissue section.
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Report
(3 results)
Research Products
(25 results)
