Research Project
Grant-in-Aid for Young Scientists (B)
Epithelial-mesenchymal transition (EMT) is an important mechanism behind the initiation of cancer invasion and metastasis. This study was performed to clarify the involvement of EMT in the progression of cholangiocarcinoma. Studies using cholangiocarcinoma cell lines and surgically resected specimens of cholangiocarcinoma demonstrated that EMT induced by transforming growth factor-β1/Snail activation was closely associated with the aggressive growth of cholangiocarcinoma, resulting in a poor prognosis.
All 2011 2010 2009
All Journal Article (4 results) (of which Peer Reviewed: 3 results) Presentation (6 results)
肝胆膵 62
Pages: 743-750
Am J Pathol 177
Pages: 141-152
Am J Pathol
Volume: 177 Pages: 141-152
Am J Pathol (In press)