| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Research Abstract |
We have described breast neuroendocrine ductal carcinoma in situ (NE-DCIS) as having characteristic clinicopathological features, such as bloody nipple discharge, low frequency of preoperative diagnosis and low-grade pathological parameters, allowing differentiation from non-NE-DCIS and, consequently, delineating this carcinoma as a distinctive variant of DCIS (Histopathology, 2008. Cytopathology, 2011. Pathol Int, 2011. J Clin Pathol, 2011. USCAP, 2010 & 2011). NE-DCIS is a tumor entity which is important for understanding the histogenesis and natural history of breast neuroendocrine tumors (B-NET), because NE-DCIS can be regarded as a preinvasive counterpart of B-NET.
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