Analysis of molecular alterations in IgG4-related sclerosing disease
| Project/Area Number |
21790349
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Human pathology
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| Research Institution | Shinshu University |
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Principal Investigator |
UEHARA Takeshi Shinshu University, 医学部, 講師 (80402121)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
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| Keywords | IgG4関連硬化性疾患 / 自己免疫性膵炎 / 胃炎 |
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| Research Abstract |
This study show diagnostic approach of IgG4-related sclerosing disease and cause investigation of IgG4-related sclerosing disease. Immunohistochemical staining was performed to IgG subclasses in the gastric biopsy got from IgG4-related sclerosing disease patient. The gastric inflammation consisted with pancreatic inflammation in IgG4-related sclerosing disease patient. The gastric biopsy is more useful than the pancreatic biopsy, so the gastric biopsy is diagnostic. Although, normal pancreatic epithelial cell and stroma cell were stimulated with human serum containing IgG subclasses, they didn't show any change.
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Report
(3 results)
Research Products
(14 results)
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[Journal Article] IgG4-related pleural diseasediagnosed by a re-evaluation ofchronic bilateral pleuritis in apatient who experienced occasionalacute left bacterial pleuritis.2011
Author(s)
Yamamoto H, Suzuki T, Yasuo M,Kobayashi O, Tsushima K, Ito M, Urushihata K, YAMAZAKI Y, Hanaoka M, Koizumi T, UEHARA T(他4 名、11 番目)
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Journal Title
InternMed 50
Pages: 893-897
Related Report
Peer Reviewed
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