マラリア原虫感染中に誘導される制御性CD4^+ T細胞が産生する制御因子の同定

• Project/Area Number: 21790408
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Parasitology (including Sanitary zoology)
• Research Institution: Nagasaki University
• Principal Investigator: KIMURA Daisuke Nagasaki University, 大学院・医歯薬学総合研究科, 助教 (50423637)
• Project Period (FY): 2009 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000); Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
• Keywords: マラリア / CD4^+ T細胞 / サイトカイン / CD4^+T細胞 / 免疫

Research Abstract

(No Summary)

Research Products

• [Journal Article] Characterization of waves of leukocyte recruitment to the lung allograft and the effect of CTLA4-Ig. (2011)
  • Author(s): T.Taguchi, Y, Inamura, K.Honma, D.Kimura, M.Miyakoda, T.Miyazaki, T.Tsuchiya, N.Yamasaki, T.Tagawa, T.Nagayasu, K.Yui
  • Journal Title: Acta medica Nagasakiensia Volume: (in press)(掲載確定)
  • Peer Reviewed
• [Journal Article] Production of IFN-γ by CD4^+ T cells in response to malaria antigens is IL-2-dependent. (2010)
  • Author(s): Kimura D, Miyakoda M, Honma K, Shibata Y, Yuda M, Chinzei Y, Yui K.
  • Journal Title: International Immunology 22 Pages: 941-952
• [Journal Article] Production of IFN-γ by CD4^+ T cells in response to malaria antigens is IL-2-dependent. (2010)
  • Author(s): Kimura D, Miyakoda M, Honma K, Shibata Y, Yuda M, Chinzei Y, Yui K.
  • Journal Title: International Immunology Volume: 22 Pages: 941-952
  • Peer Reviewed
• [Journal Article] Characterization of waves of leukocyte recruitment to the lung allograft and the effect of CTLA4-Ig.
  • Author(s): T.Taguchi, Y, Inamura, K.Honma, D.Kimura, M.Miyakoda, T.Miyazaki, T.Tsuchiya, N.Yamasaki, T.Tagawa, T.Nagayasu, K.Yui
  • Journal Title: Acta medica Nagasakiensia in press
• [Presentation] マラリア原虫感染における抗原特異的CD4^+T細胞のIFN-γ産生はIL-2依存的である (2010)
  • Author(s): 木村大輔
  • Organizer: 感染症沖縄フォーラム
  • Place of Presentation: 沖縄
  • Year and Date: 2010-02-11
• [Presentation] マラリア原虫感染における抗原特異的CD4^+ T細胞のIFN-γ産生はIL-2依存的である (2010)
  • Author(s): 木村大輔、都田真奈、本間季里、木村一美、油田正夫、鎮西康雄、由井克之
  • Organizer: 感染症沖縄フォーラム
  • Place of Presentation: 沖縄
• [Presentation] CD4^+ T細胞のマラリア原虫抗原特異的IFN-γ産生はIL-2依存的である (2010)
  • Author(s): 木村大輔、都田真奈、本間季里、木村一美、油田正夫、鎮西康雄、由井克之
  • Organizer: 第79日本寄生虫学会
  • Place of Presentation: 旭川
• [Presentation] Production of IFN-γby CD4^+ T cells in response to malaria antigen is IL-2-dependent (2010)
  • Author(s): Daisuke Kimura, Mana Miyakoda, Kiri Honma, Kazumi Kimura, Masao Yuda, Yasuo Chinzei, Katsuyuki Yui
  • Organizer: 第14回国際免疫学会
  • Place of Presentation: 神戸
• [Presentation] CD4^+T細胞のマラリア原虫抗原特異的IFN-γ産生はIL-2依存的である (2010)
  • Author(s): 木村大輔
  • Organizer: 第79日本寄生虫学会
  • Place of Presentation: 旭川
• [Presentation] CD4^+ T-cells produce IFN-γ in IL-2-dependent manner during infection with Plasmodium berghei ANKA (2010)
  • Author(s): 木村大輔
  • Organizer: 第14回国際免疫学会
  • Place of Presentation: 神戸
• [Presentation] CD4^+T-cells from mice infected with Plasmdium berghei ANKA produce high levels of IFN-γ in response to cytokine-like molecule generated by other CD4^+T cells (2009)
  • Author(s): 木村大輔
  • Organizer: 日本免疫学会
  • Place of Presentation: 大阪
  • Year and Date: 2009-12-02
• [Presentation] CD4^+ T-cells from mice infected with Plasmodium berghei ANKA produce high levels of IFN-γ in response to cytokine-like molecule generated by other CD4^+ T cells (2009)
  • Author(s): Daisuke Kimura, Mana Miyakoda, Kiri Honma, Kazumi Kimura, Katsuyuki Yui
  • Organizer: 日本免疫学会
  • Place of Presentation: 大阪
• [Remarks] ホームページ等
  • URL: http://www.med.nagasaki-u.ac.jp/mmi/im/index.html
• [Remarks]
  • URL: http://www.med.nagasaki-u.ac.jp/mmi/im/index.html