Research Project
Grant-in-Aid for Young Scientists (B)
We found that Listeria monocytogenes ActA, a surface protein required for actin polymerization and actin-based bacterial motility, plays a pivotal role in evading autophagy, but in a manner independent of bacterial motility. L. monocytogenes expressing ActA mutants that lack the ability to recruit the host proteins initially underwent ubiquitylation, followed by recruitment of p62 and LC3, before finally undergoing autophagy. We found that the involvement of Afp, newly discovered Atg5-interacting protein, in autophagy targeting Shigella.
All 2011 2010 2009 Other
All Journal Article (22 results) (of which Peer Reviewed: 10 results) Remarks (3 results)
Autophagy 7
Curr Opin Microbiol 14
Pages: 16-23
Autophagy
Volume: 7 Pages: 310-314
Cell Host Microbes
Volume: 8 Pages: 20-35
Curr Opin Microbiol
Volume: 14 Pages: 16-23
Virulence 1
Pages: 52-55
Cell Host Microbe 8
Pages: 20-35
Nat Cell Biol 12
蛋白質核酸酵素 54
Pages: 988-995
40016686010
臨床検査 53
Pages: 1569-1575
Nat Cell Biol 11
Pages: 1233-1240
Autophagy 5
Pages: 1220-1221
Methods Enzymol 452
Pages: 363-381
Nature
Curr Top Microbiol Immunol 337
Pages: 231-255
Pages: 363-81
Nature 459
Pages: 578-582
Pages: 66-73
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