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Control of tumor formation after transplantation in regenerative therapy with genetic engineering methods

Research Project

Project/Area Number 21790528
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Applied pharmacology
Research InstitutionThe Institute of Physical and Chemical Research

Principal Investigator

TAHARA Tsuyoshi  The Institute of Physical and Chemical Research, 分子プローブ機能評価研究チーム, 研究員 (20419708)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2009: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords再生医療 / がん / HSV-TK / 癌
Research Abstract

Gene therapy and cell transplantation therapy is expected to be a breakthrough for treating neurodegenerative disorders, such as Parkinson's and Alzheimer's disease. In this study, I could isolate the tumor- or non-differentiated cell-specific promoter region from Oct3/4 gene promoter and make the GFP expression vector, which works only in non-differentiated cell, such as mouse embryonic EB5 cell but not mouse fibroblast Balb/3T3b cells.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

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