Research for diagnosistic power and cost effectiveness of auto-antibody with data mining
| Project/Area Number |
21790534
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Laboratory medicine
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| Research Institution | Kobe University |
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Principal Investigator |
NISHIMURA Kunihiro Kobe University, 大学院・医学研究科, 客員准教授 (70397834)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | メタアナリシス / データマイニング / 自己抗体 / 膠原病 / 費用効果分析 / 医療費 / データマインニング |
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| Research Abstract |
We showed the efficacy of the following serum markers; KL-6 and SP-D for interstitial pneumonia and beta-D glucan for fungal infection. Both of the diseases are very serious complications for the rheumatic diseases. We also proved significant relationship between Salazosulfapyridine, one of the common Disease Modifying Antirheumatic Drugs, and its side effect through the Single Nucleotide Polymorphism of its metabolic enzyme. These findings will be helpful to the diagnosis and treatment of the rheumatic diseases.
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Report
(3 results)
Research Products
(38 results)
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[Journal Article] Association of four genetic loci with uric acid levels and reduced renal function : the J-SHIP Suita study2010
Author(s)
Tabara Y, Kohara K, Kawamoto R, Hiura Y, Nishimura K, Morisaki T, Kokubo Y,Okamura T, Tomoike H, Iwai N, Miki T
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Journal Title
Am J Nephrology 32(3)
Pages: 279-86
Related Report
Peer Reviewed
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[Journal Article] Plasma tetrahydrobiopterin/dihydrobiopterin ratio : a possible marker of endothelial dysfunction.2009
Author(s)
Takeda M, Yamashita T, Shinohara M, Sasaki N, Takaya T, Nakajima K, Inoue N, Masano T, Tawa H, Satomi-Kobayashi S, Toh R, Sugiyama D, Nishimura K, Yokoyama M, Hirata K, Kawashima S.
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Journal Title
NAID
Related Report
Peer Reviewed
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[Journal Article] Plasma tetrahydrobiopterin/dihydrobiopterin ratio : a possible marker of endothelial dysfunction.2009
Author(s)
Takeda M, Yamashita T, Shinohara M, Sasaki N, Takaya T, Nakajima K, Inoue N, Masano T, Tawa H, Satomi-Kobayashi S, Toh R, Sugiyama D, Nishimura K, Yokoyama M, Hirata K, Kawashima S.
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Journal Title
NAID
Related Report
Peer Reviewed
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[Journal Article] Association of four genetic loci with uric acid levels and reduced renal function : the J-SHIP Suita study
Author(s)
Tabara Y, Kohara K, Kawamoto R, Hiura Y, Nishimura K, Morisaki T, Kokubo Y, Okamura T, Tomoike H, Iwai N, Miki T
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Journal Title
Am J Nephrology
Volume: (In press)
Related Report
Peer Reviewed
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