| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Research Abstract |
This study evaluated the physiologic properties of high carbohydrate diet and high fat diet (low carbohydrate diet) by examining its effects on body fat and fatty liver in mice. Mice were fed three experimental diets that were high carbohydrate diet, high fat diet and normal diet. The high carbohydrate and high fat groups were tendencies to increase body weight than normal group. In analysis of gene expressions for the lipid metabolism enzymes and its regulator, de novo lipogenesis in liver of the high carbohydrate group with onset of fatty liver was activated. In further study, Future studies are required to investigate the fatty liver onset by the high carbohydrate diet gives to obesity.
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