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Association between endothelium delived microparticle and endothelial dysfunction-evaluation method of the endothelial function with blood biomarker-

Research Project

Project/Area Number 21790563
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Hygiene
Research InstitutionKurume University

Principal Investigator

ANEGAWA Takahiro  Kurume University, 医学部, 助教 (00511833)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords血管内皮機能 / 内皮由来マイクロパーティクル / フローサイトメトリー / Flow mediated vasodilatation / 予防医学 / 喫煙 / 内皮機能 / マイクロパーティクル / flow mediated dilatation
Research Abstract

We established a high specificity method of measuring endothelium delived microparticles (EMP). We examined whether smoking by young health people associate with endothelial function. Number of EMP has not significant difference between smoker and non-smoker. Reduction of EMP by quit smoking was not recognized.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (16 results)

All 2011 2010

All Journal Article (7 results) (of which Peer Reviewed: 7 results) Presentation (7 results) Patent(Industrial Property Rights) (2 results)

  • [Journal Article] Enhanced cardiac inflammation and fibrosis in ovariectomized hypertensive rats -a possible mechanism of diastolic dy sfunction in postmenopausal women-.2011

    • Author(s)
      Mori T, Anegawa T
    • Journal Title

      Hy pertens Res. 34

      Pages: 496-502

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Enhanced cardiac inflammation and fibrosis in ovariectomized hypertensive rats-a possible mechanism of diastolic dysfunction in postmenopausal women-2011

    • Author(s)
      Mori T, ほか9名8番目
    • Journal Title

      Hypertens Res.

      Volume: 34 Pages: 496-502

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Simvastatin prevents large bl ood pressure variability-induced aggravati on of cardiac hypertrophy in hypertensive rats by inhibiting RhoA/Ras-ERK pathw ays.2010

    • Author(s)
      Takayama N, Anegawa T
    • Journal Title

      Hypertens Res. 34

      Pages: 341-347

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 非弁膜性心房細動に伴う脳梗塞の重症度・転帰とCHADS2スコアとの関連に関する研究2010

    • Author(s)
      姉川敬裕
    • Journal Title

      脳卒中 32

      Pages: 129-132

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Simvastatin prevents large blood pressure variability-induced aggravation of cardiac hypertrophy in hypertensive rats by inhibiting RhoA/Ras-ERK pathways.2010

    • Author(s)
      Takayama N, ほか8名5番目
    • Journal Title

      Hypertens Res.

      Volume: 34 Pages: 341-347

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 非弁膜性心房細動に伴う脳梗塞の重症度・転帰とCHADS2スコアとの関連に関する研究2010

    • Author(s)
      姉川敬裕, ほか5名1番目
    • Journal Title

      脳卒中

      Volume: 32 Pages: 129-132

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 非弁膜性心房細動に伴う脳梗塞の重傷度・転帰とCHADS_2スコアとの関連に関する研究2010

    • Author(s)
      姉川敬裕, 他5名1番目
    • Journal Title

      脳卒中 Japanese Journal of Stroke 32

      Pages: 129-132

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] 脳梗塞超急性期におけるリモートデスクトップサービス(Logmein[○!R])を介したearly CT signs評価の信頼性2010

    • Author(s)
      姉川敬裕
    • Organizer
      第13回日本栓子検出と治療学会
    • Place of Presentation
      福岡
    • Year and Date
      2010-11-19
    • Related Report
      2010 Final Research Report
  • [Presentation] 脳梗塞超急性期におけるリモートデスクトップサービス(Logmein^[○!R]を介したearly CT signs評価の信頼性2010

    • Author(s)
      姉川敬裕
    • Organizer
      第13回日本栓子検出と治療学会
    • Place of Presentation
      福岡
    • Year and Date
      2010-11-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] 高血圧性脳症の臨床症状に伴い穿通枝領域の可逆的浮腫を認めた症例2010

    • Author(s)
      姉川敬裕
    • Organizer
      第33回日本高血圧学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2010-10-17
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] 脳梗塞超急性期におけるリモートデスクトップサービス(Logmein[○!R])を介したearly CT signs 評価の信頼性2010

    • Author(s)
      姉川敬裕
    • Organizer
      第33回日本高血圧学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2010-10-17
    • Related Report
      2010 Final Research Report
  • [Presentation] 脳梗塞超急性期におけるリモートデスクトップサービス(Logmein^[○!R])を介したearly CT signs評価の信頼性2010

    • Author(s)
      姉川敬裕
    • Organizer
      第33回日本高血圧学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2010-10-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] リモートデスクトップサービス(Logmein[○!R])を介したASPECTS 評価の信頼性2010

    • Author(s)
      姉川敬裕
    • Organizer
      第35回日本脳卒中学会総会
    • Place of Presentation
      盛岡
    • Year and Date
      2010-04-17
    • Related Report
      2010 Final Research Report
  • [Presentation] リモートデスクトップサービス(Logmein^[○!R])を介したASPECTS評価の信頼性2010

    • Author(s)
      姉川敬裕
    • Organizer
      第35回日本脳卒中学会総会
    • Place of Presentation
      盛岡
    • Year and Date
      2010-04-17
    • Related Report
      2010 Annual Research Report
  • [Patent(Industrial Property Rights)] 画像診断における二次元の診断画像の理解を助ける方法及び装置2011

    • Inventor(s)
      姉川敬裕
    • Industrial Property Rights Holder
      学校法人久留米大学
    • Filing Date
      2011-01-17
    • Related Report
      2010 Final Research Report
  • [Patent(Industrial Property Rights)] 画像診断における二次元の診断画像の理解を助ける方法及び装置2011

    • Inventor(s)
      姉川敬裕
    • Industrial Property Rights Holder
      学校法人久留米大学
    • Filing Date
      2011-01-17
    • Related Report
      2010 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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