| Project/Area Number |
21790623
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
General internal medicine (including Psychosomatic medicine)
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| Research Institution | University of Toyama |
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Principal Investigator |
FUJIMOTO Takako University of Toyama, 人間発達科学部, 講師 (70377266)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 糖尿病 / 和漢薬 / 生活習慣病 / インスリン抵抗性 |
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| Research Abstract |
In this study, to accumulate the scientific evidences about the effects of traditional medicines on life style-related diseases, we investigated the effects of Hachimijiogan and Bouiougito on diet-induced-insulin resistance in rats fed with high-fat diet and fructose-fed rats, animal models of type 2 diabetes. From these results, it was suggested that Hachimijiogan exerts beneficial effects on insulin resistance by the regulation of adipocytokine gene expression, although further experiments is needed to explain the detail mechanisms.
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