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In silico study of mechanism and therapy of chronic atrial fibrillation based on the human atrial numerical model

Research Project

Project/Area Number 21790717
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Circulatory organs internal medicine
Research InstitutionShiga University of Medical Science

Principal Investigator

ASHIHARA Takashi  滋賀医科大学, 医学部, 助教 (80396259)

Project Period (FY) 2009 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords分子心臓病態学 / 不整脈学 / 分子心臓病学 / 不整脈治療学
Research Abstract

We constructed the computer model of human atria, and conducted simulations (in silico) of chronic atrial fibrillation (AF). Then we found that fibroblast proliferation promotes AF chronicity and forms complex fractionated atrial electrogram (CFAE), known as the effective ablation target for chronic AF (Fibroblast-CFAE hypothesis). Our findings could contribute to better understanding of the mechanisms underlying CFAE-targeted AF ablation, and will improve the outcome of refractory chronic AF ablation.

Report

(5 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (184 results)

All 2013 2012 2011 2010 2009 Other

All Journal Article (50 results) (of which Peer Reviewed: 18 results) Presentation (118 results) (of which Invited: 13 results) Book (11 results) Remarks (5 results)

  • [Journal Article] Symposia:構造的リモデリング下の心房筋における興奮伝播のシミュレーション2013

    • Author(s)
      芦原貴司
    • Journal Title

      日本生理学会誌

      Volume: (in press)

    • Related Report
      2012 Final Research Report
  • [Journal Article] 心電図・不整脈との格闘:コンピュータモデリング:心電学・不整脈学領域のシミュレーション2013

    • Author(s)
      芦原貴司
    • Journal Title

      日本心電学会 30 周年記念誌

      Volume: (in press)

    • Related Report
      2012 Final Research Report
  • [Journal Article] 不整脈の診断と治療:ここまできたテクニックとテクノロジー:不整脈診断のためのコンピュータシミュレーション解析2013

    • Author(s)
      芦原貴司
    • Journal Title

      循環器内科

      Volume: 73 Pages: 507-513

    • Related Report
      2012 Final Research Report
  • [Journal Article] イオンチャネル病のすべて:コンピュータシミュレーションと遺伝性不整脈2013

    • Author(s)
      芦原貴司
    • Journal Title

      医学のあゆみ

      Volume: 245 Pages: 507-513

    • Related Report
      2012 Final Research Report
  • [Journal Article] 心房細動と心原性脳塞栓症の最近の話題2013

    • Author(s)
      芦原貴司
    • Journal Title

      大津市医師会誌

      Volume: 36 Pages: 83-86

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Journal Article] 連載「モデル解析の視点」:第5回「プルキンエ線維は電気的除細動の成否に関与するのかしないのか?」2013

    • Author(s)
      芦原貴司
    • Journal Title

      心電図

      Volume: 33 Pages: 89-92

    • Related Report
      2012 Final Research Report
  • [Journal Article] The role of fibroblasts in complex fractionated electrograms during persistent/permanent atrial fibrillation : Implications for electrogram-based catheter ablation2012

    • Author(s)
      Ashihara T, Haraguchi R, Nakazawa K, Namba T, Ikeda T, Nakazawa Y, Ozawa T, Ito M, Horie M, Trayanova NA
    • Journal Title

      Circ Res

      Volume: 110 Issue: 2 Pages: 275-284

    • DOI

      10.1161/circresaha.111.255026

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Pharmacological Blockade of <I>I</I><SUB>Ks</SUB> Destabilizes Spiral-Wave Reentry Under <I>&beta;</I>-Adrenergic Stimulation in Favor of Its Early Termination2012

    • Author(s)
      Kato S, Ashihara T, et al.
    • Journal Title

      Journal of Pharmacological Sciences

      Volume: 119 Issue: 1 Pages: 52-63

    • DOI

      10.1254/jphs.12008FP

    • NAID

      10030760299

    • ISSN
      1347-8613, 1347-8648
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] KCNE3 T4A as a genetic background of Brugada-pattern electrocardiogram2012

    • Author(s)
      Nakajima T, Ashihara T, et al.
    • Journal Title

      Circ J

      Volume: 76 Pages: 2763-2772

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Regional cooling facilitates termination of spiral-wave reentry through unpinning of rotors in rabbit hearts2012

    • Author(s)
      Yamazaki M, Ashihara T, et al.
    • Journal Title

      Heart Rhythm

      Volume: 9 Issue: 1 Pages: 107-114

    • DOI

      10.1016/j.hrthm.2011.08.013

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Kinematic Approach for Efficient and Robust Simulation of the Cardiac Beating Motion2012

    • Author(s)
      Ijiri T, Ashihara T, Umetani N, Igarashi T, Haraguchi R, Yokota H, Nakazawa K
    • Journal Title

      PloS One

      Volume: 7(5) Issue: 5 Pages: 1-9

    • DOI

      10.1371/journal.pone.0036706

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 平成二十三年度各賞受賞者紹介:荻野賞2012

    • Author(s)
      芦原貴司
    • Journal Title

      生体医工学

      Volume: 250 Pages: 716-717

    • Related Report
      2012 Final Research Report
  • [Journal Article] 心房細動の診断と治療2012

    • Author(s)
      芦原貴司
    • Journal Title

      大津市医師会誌

      Volume: 35 Pages: 89-93

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Journal Article] 連載「モデル解析の視点」:第4回「トンネル伝播仮説で電気的除細動の強度-反応曲線を説明できるか?」2012

    • Author(s)
      芦原貴司
    • Journal Title

      心電図

      Volume: 32 Pages: 443-447

    • Related Report
      2012 Final Research Report
  • [Journal Article] 連載「モデル解析の視点」:第3回「心室壁内部の分極を可視化して電気的除細動のメカニズムに迫る」2012

    • Author(s)
      芦原貴司
    • Journal Title

      心電図

      Volume: 32 Pages: 363-366

    • Related Report
      2012 Final Research Report
  • [Journal Article] 連載「モデル解析の視点」:第2回「電気的除細動において心室壁の内部は分極するのかしないのか?」2012

    • Author(s)
      芦原貴司
    • Journal Title

      心電図

      Volume: 32 Pages: 249-252

    • Related Report
      2012 Final Research Report
  • [Journal Article] 連載「モデル解析の視点」:第1回「電気的除細動では心臓全体が脱分極してリセットされるのか?」2012

    • Author(s)
      芦原貴司
    • Journal Title

      心電図

      Volume: 32 Pages: 161-164

    • Related Report
      2012 Final Research Report
  • [Journal Article] interview:研究の窓辺2012

    • Author(s)
      芦原貴司
    • Journal Title

      血圧

      Volume: 19(12) Pages: 110-111

    • Related Report
      2012 Final Research Report
  • [Journal Article] KCNE3 T4A as the Genetic Basis of Brugada-Pattern Electrocardiogram2012

    • Author(s)
      Nakajima T, Ashihara T, et al.
    • Journal Title

      Circulation Journal

      Volume: 76 Issue: 12 Pages: 2763-2772

    • DOI

      10.1253/circj.CJ-12-0551

    • NAID

      10031126046

    • ISSN
      1346-9843, 1347-4820
    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 平成二十三年度各賞受賞者紹介:荻野賞2012

    • Author(s)
      芦原貴司
    • Journal Title

      生体医工学

      Volume: 50 Pages: 716-717

    • Related Report
      2012 Annual Research Report
  • [Journal Article] J波を伴う特発性心室細動におけるデバイス治療の工夫と有効性:心室細動のトリガーとなる心室期外収縮の抑制について2012

    • Author(s)
      八尾武憲,芦原貴司ほか
    • Journal Title

      心電図

      Volume: 32(Suppl.1) Pages: 51-57

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] interview:研究の窓辺2012

    • Author(s)
      芦原貴司
    • Journal Title

      血圧

      Volume: 19(12) Pages: 110-111

    • Related Report
      2012 Annual Research Report
  • [Journal Article] トンネル伝播仮説で電気的除細動の強度-反応曲線を説明できるか?2012

    • Author(s)
      芦原貴司
    • Journal Title

      心電図

      Volume: 32 Pages: 443-447

    • NAID

      130005088222

    • Related Report
      2012 Annual Research Report
  • [Journal Article] 心室壁内部の分極を可視化して電気的除細動のメカニズムに迫る2012

    • Author(s)
      芦原貴司
    • Journal Title

      心電図

      Volume: 32 Pages: 363-366

    • NAID

      130005088214

    • Related Report
      2012 Annual Research Report
  • [Journal Article] 電気的除細動において心室壁の内部は分極するのかしないのか?2012

    • Author(s)
      芦原貴司
    • Journal Title

      心電図

      Volume: 32 Pages: 249-252

    • NAID

      130005088198

    • Related Report
      2012 Annual Research Report
  • [Journal Article] 電気的除細動では心臓全体が脱分極してリセットされるのか?2012

    • Author(s)
      芦原貴司
    • Journal Title

      心電図

      Volume: 32 Pages: 161-164

    • NAID

      130005086435

    • Related Report
      2012 Annual Research Report
  • [Journal Article] Roles of subcellular Na+ channel distributions in the mechanism of cardiac conduction2011

    • Author(s)
      Tsumoto K, Ashihara T, et al.
    • Journal Title

      Biophys J

      Volume: 100 Issue: 3 Pages: 554-563

    • DOI

      10.1016/j.bpj.2010.12.3716

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Bepridil Facilitates Early Termination of Spiral-Wave Reentry in Two-Dimensional Cardiac Muscle Through an Increase of Intercellular Electrical Coupling2011

    • Author(s)
      Takanari H, Ashihara T, et al.
    • Journal Title

      Journal of Pharmacological Sciences

      Volume: 115 Issue: 1 Pages: 15-26

    • DOI

      10.1254/jphs.10233FP

    • NAID

      10029891366

    • ISSN
      1347-8613, 1347-8648
    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Transmural Dispersion of Repolarization Determines Scroll Wave Behavior During Ventricular Tachyarrhythmias - A Simulation Study -2011

    • Author(s)
      Haraguchi R, Ashihara T, Namba T, Tsumoto K, Murakami S, Kurachi Y, Ikeda T, Nakazawa K
    • Journal Title

      Circulation Journal

      Volume: 75 Issue: 1 Pages: 80-88

    • DOI

      10.1253/circj.CJ-10-0071

    • NAID

      10027425485

    • ISSN
      1346-9843, 1347-4820
    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Modeling defibrillation of the heart: Approaches and insights2011

    • Author(s)
      Trayanova N, Ashihara T, et al.
    • Journal Title

      IEEE Rev Biomed Eng

      Volume: 4 Pages: 89-102

    • DOI

      10.1109/rbme.2011.2173761

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Identification and functional characterization of KCNQ1 mutations around the exon 7-intron 7 junction affecting the splicing process2011

    • Author(s)
      Tsuji-Wakisaka K, Ashihara T, et al.
    • Journal Title

      BBA-Molecular Basis of Disease

      Volume: 1812 Issue: 11 Pages: 1452-1459

    • DOI

      10.1016/j.bbadis.2011.07.011

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 循環器疾患の遺伝子診断と発症機序解明への多面的アプローチ:システムバイオロジーと遺伝性不整脈2011

    • Author(s)
      芦原貴司
    • Journal Title

      循環器内科

      Volume: 70 Pages: 483-492

    • Related Report
      2012 Final Research Report
  • [Journal Article] 循環器系のシミュレーション医学:バイドメインモデルによる電気的除細動メカニズムの研究2011

    • Author(s)
      芦原貴司
    • Journal Title

      医学のあゆみ

      Volume: 238 Pages: 229-236

    • Related Report
      2012 Final Research Report
  • [Journal Article] システムバイオロジーと遺伝性不整脈2011

    • Author(s)
      芦原貴司
    • Journal Title

      循環器内科

      Volume: 70 Pages: 483-492

    • Related Report
      2011 Annual Research Report
  • [Journal Article] バイドメインモデルによる電気的除細動メカニズムの研究2011

    • Author(s)
      芦原貴司
    • Journal Title

      医学のあゆみ

      Volume: 238 Pages: 229-236

    • Related Report
      2011 Annual Research Report
  • [Journal Article] Roles of subcellular Na+ channel distributions in the mechanism of cardiac conduction.2011

    • Author(s)
      Tsumoto K, Ashihara T, et al.
    • Journal Title

      Biophys J

      Volume: 100 Pages: 554-563

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Bepridil facilitates early termination of spiral-wave reentry in 2-dimensional cardiac muscle through an increase of intercellular electrical coupling.2011

    • Author(s)
      Takanari H, Ashihara T, et al.
    • Journal Title

      Pharmacol Sci

      Volume: 115 Pages: 15-26

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Transmural dispersion of repolarization determines scroll wave behavior during ventricular tachyarrhythmias.2011

    • Author(s)
      Haraguchi R, Ashihara T, et al.
    • Journal Title

      Circ J

      Volume: 75 Pages: 80-88

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Tunnel propagation following defibrillation with ICD shocks: Hidden postshock activations in the left ventricular wall underlie isoelectric window2010

    • Author(s)
      Constantino J, Ashihara T, et al.
    • Journal Title

      Heart Rhythm

      Volume: 7 Issue: 7 Pages: 953-961

    • DOI

      10.1016/j.hrthm.2010.03.026

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] イベントレコーダーの費用対効果とその解釈2010

    • Author(s)
      芦原貴司
    • Journal Title

      心電図

      Volume: 30 Pages: 225-226

    • NAID

      130000432009

    • Related Report
      2012 Final Research Report
  • [Journal Article] ここまで進んだ:不整脈研究の最新動向:不整脈研究の最先端:コンピュータシミュレーションの不整脈研究への応用2010

    • Author(s)
      芦原貴司
    • Journal Title

      医学のあゆみ

      Volume: 234 Pages: 644-651

    • Related Report
      2012 Final Research Report
  • [Journal Article] Tunnel propagation following defibrillation with ICD shocks : Hiddenpostshock activations in the left ventricular wall underlie isoelectric window.2010

    • Author(s)
      Constantino J, Ashihara T, et al.
    • Journal Title

      Heart Rhythm

      Volume: 7 Pages: 953-961

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 不整脈研究の最先端:コンピュータシミュレーションの不整脈研究への応用2010

    • Author(s)
      芦原貴司
    • Journal Title

      医学のあゆみ

      Volume: 234 Pages: 644-651

    • Related Report
      2010 Annual Research Report
  • [Journal Article] 心臓モデリングとコンピュータシミュレーションが導く不整脈研究の世界2010

    • Author(s)
      中沢一雄, 芦原貴司, ほか
    • Journal Title

      心臓

      Volume: 42(Suppl.4) Pages: 208-215

    • NAID

      130002146701

    • Related Report
      2010 Annual Research Report
  • [Journal Article] 致死的不整脈のin silico 研究:心臓電気生理の理解を深めるために2009

    • Author(s)
      芦原貴司
    • Journal Title

      臨牀と研究

      Volume: 86 Pages: 803-809

    • Related Report
      2012 Final Research Report
  • [Journal Article] 致死的不整脈のin silico研究:心臓電気生理の理解を深めるために.2009

    • Author(s)
      芦原貴司
    • Journal Title

      臨牀と研究 86

      Pages: 803-809

    • Related Report
      2009 Annual Research Report
  • [Journal Article] 心筋症に伴う不整脈薬物療法:アミオダロン療法を中心に.2009

    • Author(s)
      芦原貴司
    • Journal Title

      循環器科 65

      Pages: 309-318

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Optical mappingによるspiral waveの解析.2009

    • Author(s)
      本荘晴朗, 芦原貴司, ほか
    • Journal Title

      心電図 29

      Pages: 231-235

    • NAID

      10026293138

    • Related Report
      2009 Annual Research Report
  • [Journal Article] クレフト電位仮説に基づいた貫壁性心室較差の再現.2009

    • Author(s)
      鈴木慎悟, 芦原貴司, ほか
    • Journal Title

      信学技報 108

      Pages: 83-88

    • NAID

      110007324607

    • Related Report
      2009 Annual Research Report
  • [Journal Article] 光学計測を用いた低温除細動における仮想電極誘発興奮伝播現象の解析.2009

    • Author(s)
      荒船龍彦, 芦原貴司, ほか
    • Journal Title

      生体医工学 47

      Pages: 514-521

    • NAID

      10031199714

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] 不整脈と薬物治療:薬剤師と医師の相互理解を深めるために2013

    • Author(s)
      芦原貴司
    • Organizer
      第3回湖南臨床薬剤師循環器カンファランス
    • Place of Presentation
      大津
    • Year and Date
      2013-03-02
    • Related Report
      2012 Final Research Report
  • [Presentation] ヒトiPS細胞由来分化心筋の薬効評価への応用可能性と限界:in silico不整脈学に携わる臨床医の視点より2013

    • Author(s)
      芦原貴司
    • Organizer
      医薬品・医療機器等レギュラトリーサイエンス総合研究事業公開シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2013-02-14
    • Related Report
      2012 Final Research Report
  • [Presentation] 構造的リモデリング下の心房筋における興奮伝播のシミュレーション2013

    • Author(s)
      芦原貴司
    • Organizer
      第90回日本生理学会大会
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report
  • [Presentation] A theoretical study on the mechanism of complex fractionated atrial electrograms with continuous deflection during chronic atrial fibrillation2013

    • Author(s)
      Ashihara T, et al. (他10 名, 筆頭)
    • Organizer
      The 77th Annual Scientific Meeting of Japanese Circulation Society
    • Place of Presentation
      横浜
    • Related Report
      2012 Final Research Report
  • [Presentation] Functional properties of CFAEs during atrial fibrillation can be explained by structural remodeling: A simulation study2013

    • Author(s)
      Ashihara T, et al.
    • Organizer
      The 40th International Congress on Electrocardiology
    • Place of Presentation
      Glasgow, スコットランド
    • Related Report
      2012 Annual Research Report
  • [Presentation] In silico不整脈学:新たな不整脈治療のために2013

    • Author(s)
      芦原貴司
    • Organizer
      第28回日本不整脈学会学術大会:教育講演
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Tunnel propagation as a unified hypothesis for electrical defibrillation by ICD shock: A theoretical study2013

    • Author(s)
      Ashihara T
    • Organizer
      第28回日本不整脈学会学術大会:パネルディスカッション
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report
  • [Presentation] 構造的リモデリング下の心房筋における興奮伝播のシミュレーション2013

    • Author(s)
      芦原貴司
    • Organizer
      第90回日本生理学会大会:シンポジウム
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report
  • [Presentation] A theoretical study on the mechanism of complex fractionated atrial electrograms with continuous deflection during chronic atrial fibrillation2013

    • Author(s)
      Ashihara T, et al.
    • Organizer
      The 77th Annual Scientific Meeting of Japanese Circulation Society
    • Place of Presentation
      Yokohama
    • Related Report
      2012 Annual Research Report
  • [Presentation] 慢性心房細動におけるComplex Fractionated Atrial Electrogramの機能的性質に関する理論的研究2013

    • Author(s)
      芦原貴司ほか
    • Organizer
      新学術領域研究「多階層生体機能学」第6回全体会議
    • Place of Presentation
      沖縄
    • Related Report
      2012 Annual Research Report
  • [Presentation] 心房細動と心原性脳塞栓症の最新の話題2012

    • Author(s)
      芦原貴司
    • Organizer
      大津市医師会例会時学術講演会
    • Place of Presentation
      大津
    • Year and Date
      2012-12-20
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Presentation] シミュレーション医学で不整脈治療メカニズムに迫る2012

    • Author(s)
      芦原貴司
    • Organizer
      藤田保健衛生大学:不整脈ラウンドテーブルミーティング
    • Place of Presentation
      豊明
    • Year and Date
      2012-12-06
    • Related Report
      2012 Final Research Report
  • [Presentation] 慢性心房細動のメカニズムと治療に関するシミュレーション2012

    • Author(s)
      芦原貴司
    • Organizer
      日本生体医工学会関西支部・講演会(BioMecForum 第67回研究会)
    • Place of Presentation
      吹田
    • Year and Date
      2012-12-01
    • Related Report
      2012 Final Research Report
  • [Presentation] シミュレーション医学で不整脈治療メカニズムに迫る2012

    • Author(s)
      芦原貴司
    • Organizer
      福島不整脈懇話会
    • Place of Presentation
      福島
    • Year and Date
      2012-07-27
    • Related Report
      2012 Final Research Report
  • [Presentation] 心房細動の機序と治療に関する最近の話題2012

    • Author(s)
      芦原貴司
    • Organizer
      第5回京都日赤循環器フォーラム
    • Place of Presentation
      京 都
    • Year and Date
      2012-06-29
    • Related Report
      2012 Final Research Report
  • [Presentation] 臨床不整脈治療の基礎から最新動向まで2012

    • Author(s)
      芦原貴司
    • Organizer
      立命館大学生命科学部生命情報学科天野研リサーチセミナー
    • Place of Presentation
      草津
    • Year and Date
      2012-02-23
    • Related Report
      2012 Final Research Report
  • [Presentation] Functional properties of complex fractionated atrial electrograms during atrial fibrillation can be explained by structural remodeling: A computational study2012

    • Author(s)
      Ashihara T, et al. (他7 名, 筆頭)
    • Organizer
      American Heart Association 84th Scientific Sessions
    • Place of Presentation
      米国
    • Related Report
      2012 Final Research Report
  • [Presentation] 慢性心房細動における種々のComplex Fractionated Atrial Electrogramは構造的リモデリングの進展で説明できるか?2012

    • Author(s)
      芦原貴司ら(他8名, 筆頭)
    • Organizer
      第28回心電情報処理ワークショップ
    • Place of Presentation
      熱海
    • Related Report
      2012 Final Research Report
  • [Presentation] 致死性不整脈の数理:バイドメインモデルによる電気的除細動メカニズムの理論的研究2012

    • Author(s)
      芦原貴司
    • Organizer
      GCOEシンポジウム「数学新展開の研究教育拠点」臨床医学における数理
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report
  • [Presentation] 慢性心房細動におけるComplex Fractionated Atrial Electrogramは機能的か?:シミュレーシンによる理論的検討2012

    • Author(s)
      芦原貴司ら(他7名, 筆頭)
    • Organizer
      第29回日本心電学会学術集会
    • Place of Presentation
      千葉
    • Related Report
      2012 Final Research Report
  • [Presentation] Mechanisms of CFAE-targeted ablation for chronic AF: A simulation study2012

    • Author(s)
      Ashihara T
    • Organizer
      The 5th Asia-Pacific Heart Rhythm Society Scientific Session in conjunction with The 8th Asia-Pacific Atrial Fibrillation Symposium
    • Place of Presentation
      台湾
    • Related Report
      2012 Final Research Report
  • [Presentation] Application of biological simulations to the studies of ventriculardefibrillation2012

    • Author(s)
      Ashihara T
    • Organizer
      The 5th Asia-Pacific Heart Rhythm Society Scientific Session in conjunction with The 8th Asia-Pacific Atrial Fibrillation Symposium
    • Place of Presentation
      台湾
    • Related Report
      2012 Final Research Report
  • [Presentation] 持続性心房細動におけるComplex Fractionated Atrial Electrogram領域の電位的特徴に関する理論的研究2012

    • Author(s)
      芦原貴司ら(他7名, 筆頭)
    • Organizer
      第27回日本不整脈学会学術大会
    • Place of Presentation
      横浜
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Presentation] 生体現象のマルチフィジックスマルチスケールシミュレーション:不整脈臨床医はマルチスケールシミュレーションに何を求めるのか?2012

    • Author(s)
      芦原貴司ら(他3名, 筆頭)
    • Organizer
      第51回日本生体医工学会大会
    • Place of Presentation
      福岡
    • Related Report
      2012 Final Research Report
  • [Presentation] Theoretical basis of optimal strategy for CFAE-targeted ablation during chronicatrial fibrillation2012

    • Author(s)
      Ashihara T, et al. (他8 名, 筆頭)
    • Organizer
      Heart Rhythm 2012 Scientific Sessions
    • Place of Presentation
      米国
    • Related Report
      2012 Final Research Report
  • [Presentation] Theoretical studies on the mechanisms of electrogram-based catheter ablation forchronic atrial fibrillation2012

    • Author(s)
      Ashihara T, et al. (他8 名, 筆頭)
    • Organizer
      The 76th Annual Scientific Meeting of Japanese Circulation Society
    • Place of Presentation
      福岡
    • Related Report
      2012 Final Research Report
  • [Presentation] 心機能評価法の新展開Frontiers in heart research:コンピュータ不整脈学が拓く新しい薬効評価法の意義2012

    • Author(s)
      芦原貴司
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      京都
    • Related Report
      2012 Final Research Report
  • [Presentation] Mechanisms of electrogram- based catheter ablation for chronic atrialfibrillation2012

    • Author(s)
      Ashihara T
    • Organizer
      The 1st HD Physiology International Symposium: Integrative Multi-level Systems Biology for In Silico Cardiology and Pharmacokinetics
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report
  • [Presentation] Functional properties of complex fractionated atrial electrograms during atrial fibrillation can be explained by structural remodeling: A computational study2012

    • Author(s)
      Ashihara T, et al.
    • Organizer
      American Heart Association (AHA) 84th Scientific Sessions
    • Place of Presentation
      Los Angeles, アメリカ合衆国
    • Related Report
      2012 Annual Research Report
  • [Presentation] 慢性心房細動における種々のComplex Fractionated Atrial Electrogramは構造的リモデリングの進展で説明できるか?2012

    • Author(s)
      芦原貴司ほか
    • Organizer
      第28回心電情報処理ワークショップ
    • Place of Presentation
      熱海
    • Related Report
      2012 Annual Research Report
  • [Presentation] 致死性不整脈の数理:バイドメインモデルによる電気的除細動メカニズムの理論的研究2012

    • Author(s)
      芦原貴司
    • Organizer
      GCOEシンポジウム「数学新展開の研究教育拠点」臨床医学における数理
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 慢性心房細動におけるComplex Fractionated Atrial Electrogramは機能的か?:シミュレーションによる理論的検討2012

    • Author(s)
      芦原貴司ほか
    • Organizer
      第29回日本心電学会学術集会
    • Place of Presentation
      千葉
    • Related Report
      2012 Annual Research Report
  • [Presentation] Mechanisms of CFAE-targeted ablation for chronic AF: A simulation study2012

    • Author(s)
      Ashihara T
    • Organizer
      The 5th Asia-Pacific Heart Rhythm Society Scientific Session (APHRS)
    • Place of Presentation
      Taipei, 台湾
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Application of biological simulations to the studies of ventricular defibrillation2012

    • Author(s)
      Ashihara T
    • Organizer
      The 5th Asia-Pacific Heart Rhythm Society Scientific Session (APHRS)
    • Place of Presentation
      Taipei, 台湾
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 不整脈臨床医はマルチスケールシミュレーションに何を求めるのか?2012

    • Author(s)
      芦原貴司ほか
    • Organizer
      第51回日本生体医工学会大会:シンポジウム
    • Place of Presentation
      福岡
    • Related Report
      2012 Annual Research Report
  • [Presentation] Theoretical basis of optimal strategy for CFAE-targeted ablation during chronic atrial fibrillation.2012

    • Author(s)
      Ashihara T, et al.
    • Organizer
      Heart Rhythm 2012 Scientific Sessions
    • Place of Presentation
      Boston, アメリカ合衆国
    • Related Report
      2012 Annual Research Report
  • [Presentation] コンピュータ不整脈学が拓く新しい薬効評価法の意義2012

    • Author(s)
      芦原貴司
    • Organizer
      第85回日本薬理学会年会:シンポジウム23「心機能評価法の新展開Frontiers in heart research」
    • Place of Presentation
      京都(招待講演)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Mechanisms of electrogram-based catheter ablation for chronic atrial fibrillation2012

    • Author(s)
      Takashi Ashihara
    • Organizer
      第1回国際シンポジウム新学術領域研究「多階層生体機能学HD Physiology」
    • Place of Presentation
      東京(招待講演)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Theoretical studies on the mechanisms of electrogram-based catheter ablation for chronic atrial fibrillation2012

    • Author(s)
      Ashihara T, et al
    • Organizer
      第76回日本循環器学会学術集会
    • Place of Presentation
      福岡
    • Related Report
      2011 Annual Research Report
  • [Presentation] Roles of subcellular sodium channel distribution in the mechanism of cardiac conduction2012

    • Author(s)
      Tsumoto K, Ashihara T, et al
    • Organizer
      第1回国際シンポジウム新学術領域研究「多階層生体機能学HD Physiology」
    • Place of Presentation
      東京
    • Related Report
      2011 Annual Research Report
  • [Presentation] Phase-2 reentry associated with subcellular sodium channel remodeling : A possible mechanism of fibrillation induction in brugada syndrome2012

    • Author(s)
      Tsumoto K, Ashihara T, et al
    • Organizer
      第1回国際シンポジウム新学術領域研究「多階層生体機能学HD Physiology」
    • Place of Presentation
      東京
    • Related Report
      2011 Annual Research Report
  • [Presentation] Phase-2 reentry associated with subcellular sodium channel remodeling : A possible mechanism of fibrillation induction in Brugada syndrome2012

    • Author(s)
      Kunichika T, Ashihara T, et al
    • Organizer
      第76回日本循環器学会学術集会
    • Place of Presentation
      福岡
    • Related Report
      2011 Annual Research Report
  • [Presentation] Na+チャネルの細胞内再分布による催不整脈性の変化:Phase-2リエントリーとの関連において2012

    • Author(s)
      Kunichika T, Ashihara T, et al
    • Organizer
      第89回日本生理学会大会
    • Place of Presentation
      松本
    • Related Report
      2011 Annual Research Report
  • [Presentation] 心房細動の診断と治療2011

    • Author(s)
      芦原貴司
    • Organizer
      大津市医師会イブニングセミナー
    • Place of Presentation
      大津(招待講演)
    • Year and Date
      2011-12-17
    • Related Report
      2011 Annual Research Report
  • [Presentation] 循環器領域における生体システム学:コンピュータ不整脈学2011

    • Author(s)
      芦原貴司
    • Organizer
      文部科学省戦略的大学連携支援事業:広域大学連携による臨床医工学・情報学高度人材育成システムの構築
    • Place of Presentation
      大阪(招待講演)
    • Year and Date
      2011-10-22
    • Related Report
      2011 Annual Research Report 2010 Annual Research Report
  • [Presentation] 心筋ナトリウムチャネルの細胞内分布変化が興奮伝導に及ぼす影響:in silico研究2011

    • Author(s)
      津元国親, 芦原貴司, ほか
    • Organizer
      第104回近畿生理学談話会
    • Place of Presentation
      大阪
    • Year and Date
      2011-10-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] 突然倒れたら、息切れがしたら・・・ 心室細動と心不全2011

    • Author(s)
      芦原貴司
    • Organizer
      第26回滋賀医科大学公開講座
    • Place of Presentation
      草津
    • Year and Date
      2011-09-06
    • Related Report
      2012 Final Research Report
  • [Presentation] 突然倒れたら、息切れがしたら…心室細動と心不全2011

    • Author(s)
      芦原貴司
    • Organizer
      第26回滋賀医科大学公開講座
    • Place of Presentation
      草津(招待講演)
    • Year and Date
      2011-09-06
    • Related Report
      2011 Annual Research Report
  • [Presentation] 理論不整脈学からみた慢性心房細動アブレーションとその展望2011

    • Author(s)
      芦原貴司
    • Organizer
      第4回Arrhythmia Expert Conference関西
    • Place of Presentation
      大阪
    • Year and Date
      2011-06-11
    • Related Report
      2012 Final Research Report
  • [Presentation] 理論不整脈学からみた慢性心房細動アブレーションとその展望2011

    • Author(s)
      芦原貴司
    • Organizer
      第4回AEC関西
    • Place of Presentation
      大阪(招待講演)
    • Year and Date
      2011-06-11
    • Related Report
      2011 Annual Research Report
  • [Presentation] 日常診療における抗凝固療法の現状と課題:心原性脳塞栓症治療の現状と課題:心房細動アブレーションとの関連において2011

    • Author(s)
      芦原貴司
    • Organizer
      滋賀県CareAF講演会
    • Place of Presentation
      大津
    • Year and Date
      2011-04-23
    • Related Report
      2012 Final Research Report
  • [Presentation] 心原性脳塞栓症治療の現状と課題:心房細動アプレーションとの関連において2011

    • Author(s)
      芦原貴司
    • Organizer
      滋賀県CareAF講演会:日本脳卒中協会共同事業CareAFプロジェクト:心房細動における脳梗塞予防の重要性
    • Place of Presentation
      大津(招待講演)
    • Year and Date
      2011-04-23
    • Related Report
      2011 Annual Research Report
  • [Presentation] コンピュータシミュレーションの不整脈研究への応用2011

    • Author(s)
      芦原貴司
    • Organizer
      新学術領域研究「多階層生体機能学」第2回全体会議
    • Place of Presentation
      大阪(招待講演)
    • Year and Date
      2011-02-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] コンピュータシミュレーションの不整脈研究への応用2011

    • Author(s)
      芦原貴司
    • Organizer
      第3回基礎・臨床融合の学内共同研究発表会:イオンチャネル研究の最前線:From Gene to Computer Simulation
    • Place of Presentation
      大津
    • Year and Date
      2011-02-02
    • Related Report
      2012 Final Research Report
  • [Presentation] コンピュータシミュレーションの不整脈研究への応用2011

    • Author(s)
      芦原貴司
    • Organizer
      第3回基礎・臨床融合共同研究発表会:イオンチャネル研究の最前線:From Gene to Computer Simulation
    • Place of Presentation
      大津(招待講演)
    • Year and Date
      2011-02-02
    • Related Report
      2010 Annual Research Report
  • [Presentation] カテーテルアブレーションで慢性心房細動を停止できるか:In silicoによるCFAE標的アブレーションの検討2011

    • Author(s)
      芦原貴司ら(他8名, 筆頭)
    • Organizer
      第27回心電情報処理ワークショップ
    • Place of Presentation
      笛吹
    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Presentation] 日本心電学会:特別企画II:コンピュータシミュレーション コンピュータ心電図の進歩:オーバービュー2011

    • Author(s)
      芦原貴司
    • Organizer
      The 4th Asia-Pacific Heart Rhythm Society Scientific Session in conjunction with The 7th Asia-Pacific Atrial Fibrillation Symposium / 26th Annual Scientific Session of the Japanese Heart Rhythm Society / 28th Annual Scientific Session of the Japanese Society of Electrocardiology
    • Place of Presentation
      福岡
    • Related Report
      2012 Final Research Report
  • [Presentation] Mechanisms of complex fractionated electrogram-targeted ablation in a model forchronic atrial fibrillation2011

    • Author(s)
      Ashihara T, et al. (他8 名, 筆頭)
    • Organizer
      The 4th Asia-Pacific Heart Rhythm Society Scientific Session in conjunction with The 7th Asia-Pacific Atrial Fibrillation Symposium / 26th Annual Scientific Session of the Japanese Heart Rhythm Society / 28th Annual Scientific Session of the Japanese Society of Electrocardiology
    • Place of Presentation
      福岡
    • Related Report
      2012 Final Research Report
  • [Presentation] Roles of fibroblasts / myofibroblasts in the mechanisms of CFAEs during chronic atrial fibrillation and CFAE-targeted catheter ablation: A simulation study2011

    • Author(s)
      Ashihara T, et al. (他9名, 筆頭)
    • Organizer
      The 75th Annual Scientific Meeting of Japanese Circulation Society
    • Place of Presentation
      横浜
    • Related Report
      2012 Final Research Report
  • [Presentation] シミュレーションで致死性不整脈とその治療メカニズムに迫る2011

    • Author(s)
      芦原貴司
    • Organizer
      第48回薬剤学懇談会研究討論会
    • Place of Presentation
      上山
    • Related Report
      2012 Final Research Report
  • [Presentation] コンピュータシミュレーションコンピュータ心電図の進歩:オーバービュー2011

    • Author(s)
      芦原貴司
    • Organizer
      日本心電学会:特別企画II
    • Place of Presentation
      福岡(招待講演)
    • Related Report
      2011 Annual Research Report
  • [Presentation] シミュレーションで致死性不整脈とその治療メカニズムに迫る2011

    • Author(s)
      芦原貴司
    • Organizer
      第48回薬剤学懇談会研究討論
    • Place of Presentation
      上山(招待講演)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Sketch-based dynamic illustration of fluid systems2011

    • Author(s)
      Zhu B, Ashihara T, et al
    • Organizer
      The 4th ACM SIGGRAPH Conference and Exhibition on Computer Graphics and Interactive Techniques in Asia
    • Place of Presentation
      Hong Kong
    • Related Report
      2011 Annual Research Report
  • [Presentation] An effcient, robust framework for simulating the brating heart2011

    • Author(s)
      Ijiri T, Ashihara T, et al
    • Organizer
      23rd Conference of the Society for Medical Innovation and Technology
    • Place of Presentation
      Tel Aviv
    • Related Report
      2011 Annual Research Report
  • [Presentation] Effects of subcellular sodium channel distribution on the initiation of phase-2 reentry : A possible mechanism of fibrillation induction in Brugada syndrome2011

    • Author(s)
      Tsumoto K, Ashihara T, et al
    • Organizer
      第4回アジア太平洋不整脈学会(APHRS)/第26回日本不整脈学会学術大会(JHRS)/第28回日本心電学会学術集会(JSE)
    • Place of Presentation
      福岡
    • Related Report
      2011 Annual Research Report
  • [Presentation] Rotational anisotropy prevents transition of tachycardia to fibrillation in the ventricular wall model with large transmural dispersion of repolarization : A simulation study2011

    • Author(s)
      Haraguchi R, Ashihara T, et al
    • Organizer
      第4回アジア太平洋不整脈学会(APHRS)/第26回日本不整脈学会学術大会(JHRS)/第28回日本心電学会学術集会(JSE)
    • Place of Presentation
      福岡
    • Related Report
      2011 Annual Research Report
  • [Presentation] Stability of ventricular fibrillation is altered by wall deformation after the onset of fibrillation2011

    • Author(s)
      Inada S, Ashihara T, et al
    • Organizer
      第4回アジア太平洋不整脈学会(APHRS)/第26回日本不整脈学会学術大会(JHRS)/第28回日本心電学会学術集会(JSE)
    • Place of Presentation
      福岡
    • Related Report
      2011 Annual Research Report
  • [Presentation] Mechanisms of complex fractionated electrogram-targeted ablation in a model for chronic atrial fibrillation2011

    • Author(s)
      Ashihara T, et al
    • Organizer
      第4回アジア太平洋不整脈学会(APHRS)/第26回日本不整脈学会学術大会(JHRS)/第28回日本心電学会学術集会(JSE)
    • Place of Presentation
      福岡
    • Related Report
      2011 Annual Research Report
  • [Presentation] Roles of fibroblasts/myofibroblasts in the mechanisms of CFAEs during chronic atrial fibrillation and CFAE-targeted catheter ablation : A simulation study2011

    • Author(s)
      Ashihara T, et al
    • Organizer
      第75回日本循環器学会学術集会
    • Place of Presentation
      横浜
    • Related Report
      2011 Annual Research Report
  • [Presentation] 光学マッピングを用いた局所低温除細動における最適冷却領域の検討2011

    • Author(s)
      荒船龍彦, 芦原貴司, ほか
    • Organizer
      第27回心電情報処理ワークショップ
    • Place of Presentation
      笛吹
    • Related Report
      2011 Annual Research Report
  • [Presentation] 幾何制約に基づく運動計算手法を用いた実時間心臓拍動シミュレーション2011

    • Author(s)
      井尻敬, 芦原貴司, ほか
    • Organizer
      第50回日本生体医工学会大会
    • Place of Presentation
      東京
    • Related Report
      2011 Annual Research Report
  • [Presentation] 心室筋厚と心室細動の持続性との関係:シミュレーションによる検討2011

    • Author(s)
      稲田慎, 芦原貴司, ほか
    • Organizer
      第50回日本生体医工学会大会
    • Place of Presentation
      東京
    • Related Report
      2011 Annual Research Report
  • [Presentation] Theoretical studies on the roles of fibroblasts in the mechanism of complexfractionated atrial electrograms and theelectrogram-based catheter ablation2010

    • Author(s)
      Ashihara T
    • Organizer
      13th Tokyo Taipei Seoul Arrhythmia Joint Conference
    • Place of Presentation
      福岡
    • Year and Date
      2010-10-02
    • Related Report
      2012 Final Research Report
  • [Presentation] Theoretical studies on the roles of fibroblasts in the mechanism of complex fractionated atrial electrograms and electrogram-based catheter ablation.2010

    • Author(s)
      Ashihara T
    • Organizer
      Tokyo Taipei Seoul Arrhythmia Joint Conference
    • Place of Presentation
      Fukuoka(招待講演)
    • Year and Date
      2010-10-02
    • Related Report
      2010 Annual Research Report
  • [Presentation] 不整脈治療に関する最近の話題:基礎から臨床まで2010

    • Author(s)
      芦原貴司
    • Organizer
      滋賀県湖南地区循環器勉強会
    • Place of Presentation
      草津
    • Year and Date
      2010-07-29
    • Related Report
      2012 Final Research Report
  • [Presentation] 不整脈治療に関する最近の話題:基礎から臨床まで2010

    • Author(s)
      芦原貴司
    • Organizer
      滋賀県湖南地区循環器勉強会
    • Place of Presentation
      草津(招待講演)
    • Year and Date
      2010-07-29
    • Related Report
      2010 Annual Research Report
  • [Presentation] 整脈治療の新たな展開2010

    • Author(s)
      芦原貴司
    • Organizer
      第108回滋賀県内科医会学術講演会
    • Place of Presentation
      近江八幡
    • Year and Date
      2010-06-19
    • Related Report
      2012 Final Research Report
  • [Presentation] 不整脈治療の新たな展開2010

    • Author(s)
      芦原貴司
    • Organizer
      第108回滋賀県内科医会学術講演会
    • Place of Presentation
      近江八幡(招待講演)
    • Year and Date
      2010-06-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] Roles of fibroblasts in the mechanisms of complex fractionated atrial electrograms and catheterablation during chronic atrial fibrillation2010

    • Author(s)
      Ashihara T, et al. (他9名, 筆頭)
    • Organizer
      The 3rd Asia-Pacific Heart Rhythm Society Scientific Session in conjunction with The 6th Asia-Pacific Atrial Fibrillation Symposium
    • Place of Presentation
      韓国
    • Related Report
      2012 Final Research Report
  • [Presentation] 慢性心房細動に対するCFAE標的アブレーションのメカニズムに関するin silico研究:線維芽細胞の役割に着目して2010

    • Author(s)
      芦原貴司ら(他10名, 筆頭)
    • Organizer
      第27回日本心電学会学術集会
    • Place of Presentation
      大分
    • Related Report
      2012 Final Research Report
  • [Presentation] 心房細動の機序の解明とそれに基づく治療戦略:Complex Fractionated Atrial Electrogramsのメカニズムにおける線維芽細胞の役割とカテーテルアブレーションに関する理論的研究2010

    • Author(s)
      芦原貴司ら(他9名, 筆頭)
    • Organizer
      第25回日本不整脈学会学術大会
    • Place of Presentation
      名古屋
    • Related Report
      2012 Final Research Report
  • [Presentation] Roles of fibroblasts in the mechanism of complex fractionated atrial electrograms during chronic atrial fibrillation2010

    • Author(s)
      Ashihara T, et al. (他9名, 筆頭)
    • Organizer
      Heart Rhythm Scientific Sessions
    • Place of Presentation
      米国
    • Related Report
      2012 Final Research Report
  • [Presentation] 循環器病研究におけるシミュレーション医学:Application of biologicalsimulations to the studies of fibrillation induction and defibrillation2010

    • Author(s)
      芦原貴司
    • Organizer
      第74回日本循環器学会学術集会
    • Place of Presentation
      京都
    • Related Report
      2012 Final Research Report
  • [Presentation] Theoretical study on the mechanisms of complex fractionated atrial electrogram- targeted atrial fibrillation ablation2010

    • Author(s)
      Ashihara T, et al. (他10 名, 筆頭)
    • Organizer
      第74回日本循環器学会学術集会
    • Place of Presentation
      京都
    • Related Report
      2012 Final Research Report
  • [Presentation] シンポジウム:心房細動の機序の解明とそれに基づく治療戦略:CFAEメカニズムにおける線維芽細胞の役割とカテーテルアブレーションに関する理論的研究2010

    • Author(s)
      芦原貴司, ほか
    • Organizer
      第25回日本不整脈学会学術大会(JHRS)
    • Place of Presentation
      名古屋
    • Related Report
      2010 Annual Research Report
  • [Presentation] Roles of fibroblasts in the mechanisms of complex fractionated atrial electrograms and catheter ablation during chronic atrial fibrillation.2010

    • Author(s)
      Ashihara T, et al.
    • Organizer
      The 3rd Asia-Pacific Heart Rhythm Society Scientific Session(APHRS 2010)
    • Place of Presentation
      Jeju Island(招待講演)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Waveform similarity between unipolar and bipolar electrical potential at QRS complex and P wave in precordial leads of electrocardiogram.2010

    • Author(s)
      Namba T, Ashihara T, et al.
    • Organizer
      The 3rd Asia-Pacific Heart Rhythm Society Scientific Session (APHRS 2010)
    • Place of Presentation
      Jeju Island
    • Related Report
      2010 Annual Research Report
  • [Presentation] Influence of pulmonary vein isolation on heart rate : A clinical study using event-ECG monitors.2010

    • Author(s)
      Nakazawa Y, Ashihara T, et al.
    • Organizer
      The 3rd Asia-Pacific Heart Rhythm Society Scientific Session (APHRS 2010)
    • Place of Presentation
      Jeju Island
    • Related Report
      2010 Annual Research Report
  • [Presentation] Roles of fibroblasts in the mechanism of complex fractionated atrial electrograms during chronic atrial fibrillation.2010

    • Author(s)
      Ashihara T, et al.
    • Organizer
      Heart Rhythm 2010 Scientific Sessions
    • Place of Presentation
      Denver
    • Related Report
      2010 Annual Research Report
  • [Presentation] インタラクティブな心臓の拍動シミュレーション手法2010

    • Author(s)
      井尻敬, 芦原貴司, ほか
    • Organizer
      第30回医療情報学連合大会(JCMI)
    • Place of Presentation
      浜松
    • Related Report
      2010 Annual Research Report
  • [Presentation] 慢性心房細動に対するCFAE標的アブレーションのメカニズムに関するin silico研究:線維芽細胞の役割に着目して2010

    • Author(s)
      芦原貴司, ほか
    • Organizer
      第27回日本心電学会学術集会(JSE)
    • Place of Presentation
      大分
    • Related Report
      2010 Annual Research Report
  • [Presentation] Irrigated ablation systemによる左房後壁の電位波高低下は安全な焼灼の指標となるか?2010

    • Author(s)
      伊藤誠, 芦原貴司, ほか
    • Organizer
      第27回日本心電学会学術集会(JSE)
    • Place of Presentation
      大分
    • Related Report
      2010 Annual Research Report
  • [Presentation] 心室線維走向ねじれは心室較差増大による催不整脈性を抑制する:3次元心室壁モデルによる理論的研究2010

    • Author(s)
      原口亮, 芦原貴司, ほか
    • Organizer
      第27回日本心電学会学術集会(JSE)
    • Place of Presentation
      大分
    • Related Report
      2010 Annual Research Report
  • [Presentation] フィードバック刺激を用いた局所低温除細動治療メカニズムの解明2010

    • Author(s)
      荒船龍彦, 芦原貴司, ほか
    • Organizer
      第27回日本心電学会学術集会(JSE)
    • Place of Presentation
      大分
    • Related Report
      2010 Annual Research Report
  • [Presentation] ラットPurkinje線維の電子顕微鏡観察2010

    • Author(s)
      山口豪, 芦原貴司, ほか
    • Organizer
      第27回日本心電学会学術集会(JSE)
    • Place of Presentation
      大分
    • Related Report
      2010 Annual Research Report
  • [Presentation] 心筋ナトリウムチャネルの細胞内局在の興奮伝導への影響2010

    • Author(s)
      津元国親, 芦原貴司, ほか
    • Organizer
      第27回日本心電学会学術集会(JSE)
    • Place of Presentation
      大分
    • Related Report
      2010 Annual Research Report
  • [Presentation] P波およびQRSにおける双極胸部誘導と単極胸部誘導の波形の比較:携帯型心電計での双極胸部誘導の波形解釈のための基礎研究2010

    • Author(s)
      難波経豊, 芦原貴司, ほか
    • Organizer
      第27回日本心電学会学術集会(JSE)
    • Place of Presentation
      大分
    • Related Report
      2010 Annual Research Report
  • [Presentation] The roles of subcellular localizations of sodium channels are to increase the conduction velocity and the safety factor of cardiac conduction in the presence of electric field mechanism.2010

    • Author(s)
      Tsumoto K, Ashihara T, et al.
    • Organizer
      The 87th Annual Meeting of the Physiological Society of Japan
    • Place of Presentation
      Morioka
    • Related Report
      2010 Annual Research Report
  • [Presentation] Theoretical study on the mechanisms of complex fractionated atrial electrogram-targeted atrial fibrillation ablation.2010

    • Author(s)
      Ashihara T, et al.
    • Organizer
      第74回日本循環器学会学術集会
    • Place of Presentation
      国立京都国際会館(京都)
    • Related Report
      2009 Annual Research Report
  • [Presentation] ミート・ザ・エキスパート7「循環器病研究におけるシミュレーション医学」:Application of biological simulations to the studies of fibrillation induction and defibrillation2010

    • Author(s)
      芦原貴司
    • Organizer
      第74回日本循環器学会学術集会
    • Place of Presentation
      国立京都国際会館(京都)
    • Related Report
      2009 Annual Research Report
  • [Presentation] 心房細動のマッピング:心臓電気生理シミュレーションから判ること2009

    • Author(s)
      芦原貴司
    • Organizer
      熊本大学医学部附属病院不整脈先端医療寄附講座主催学術講演会
    • Place of Presentation
      熊本
    • Year and Date
      2009-12-02
    • Related Report
      2012 Final Research Report
  • [Presentation] 心房細動のマッピング:心臓電気生理シミュレーションから判ること.2009

    • Author(s)
      芦原貴司
    • Organizer
      熊本大学附属病院不整脈先端医療寄附講座学術講演会
    • Place of Presentation
      三井ガーデンホテル(熊本)
    • Year and Date
      2009-12-02
    • Related Report
      2009 Annual Research Report
  • [Presentation] 循環器領域における生体システム学:コンピュータ不整脈学.2009

    • Author(s)
      芦原貴司
    • Organizer
      文部科学省戦略的大学連携支援事業:広域大学連携による「臨床医工学・情報学」高度人材育成システムの構築
    • Place of Presentation
      中之島センター(大阪)
    • Year and Date
      2009-10-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] コンピュータ不整脈学が創る未来:生体シミュレーションの不整脈研究への応用2009

    • Author(s)
      芦原貴司
    • Organizer
      第24回日本不整脈学会学術大会/第26回日本心電学会学術集会
    • Place of Presentation
      京都
    • Related Report
      2012 Final Research Report
  • [Presentation] Tunnel propagation of postshock activations as a hypothesis for fibrillation induction and isoelectric window2009

    • Author(s)
      芦原貴司
    • Organizer
      第24回日本不整脈学会学術大会/第26回日本心電学会学術集会
    • Place of Presentation
      京都
    • Related Report
      2012 Final Research Report
  • [Presentation] Steep restitution slope is not an essential factor for microvolt-level T-wave alternans: Insights from computer simulations.2009

    • Author(s)
      Ashihara T, et al. (他7名, 筆頭)
    • Organizer
      The 13th Congress of the International Society for Holter and Noninvasive Electrocardiology
    • Place of Presentation
      横浜
    • Related Report
      2012 Final Research Report
  • [Presentation] パネルディスカッションIV「コンピュータ不整脈学が創る未来」:生体シミュレーションの不整脈研究への応用.2009

    • Author(s)
      芦原貴司
    • Organizer
      第24回日本不整脈学会学術大会/第26回日本心電学会学術集会合同学術集会
    • Place of Presentation
      国立京都国際会館(京都)
    • Related Report
      2009 Annual Research Report
  • [Presentation] 日本心電学会学術奨励賞最終選考会:Tunnel propagation of postshock activations as a hypothesis for fibrillation induction and isoelectric window.2009

    • Author(s)
      芦原貴司
    • Organizer
      第24回日本不整脈学会学術大会/第26回日本心電学会学術集会合同学術集会
    • Place of Presentation
      国立京都国際会館(京都)
    • Related Report
      2009 Annual Research Report
  • [Presentation] Steep restitution slope is not an essential factor for microvolt-level T-wave alternans : Insights from computer simulations.2009

    • Author(s)
      Ashihara T, et al.
    • Organizer
      The 13th Congress of the International Society for Holter and Noninvasive Electrocardiology
    • Place of Presentation
      横浜ベイシェラトンホテル&タワーズ(横浜)
    • Related Report
      2009 Annual Research Report
  • [Presentation] カテーテルアブレーションでスパイラルリエントリーを停止できるか?

    • Author(s)
      芦原貴司
    • Organizer
      第4回EP Expertsカンファレンス
    • Place of Presentation
      福岡
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 心房細動の機序と治療に関する最近の話題

    • Author(s)
      芦原貴司
    • Organizer
      第21回Hertz Bessern
    • Place of Presentation
      京都
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 不整脈と薬物治療:薬剤師と医師の相互理解を深めるために

    • Author(s)
      芦原貴司
    • Organizer
      第3回湖南臨床薬剤師循環器カンファランス
    • Place of Presentation
      大津
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] ヒトiPS細胞由来分化心筋の薬効評価への応用可能性と限界:in silico不整脈学に携わる臨床医の視点より

    • Author(s)
      芦原貴司
    • Organizer
      医薬品・医療機器等レギュラトリーサイエンス総合研究事業:公開シンポジウム
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] シミュレーション医学で不整脈治療メカニズムに迫る

    • Author(s)
      芦原貴司
    • Organizer
      藤田保健衛生大学第10回不整脈ラウンドテーブルミーティング
    • Place of Presentation
      豊明
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 慢性心房細動のメカニズムと治療に関するシミュレーション

    • Author(s)
      芦原貴司
    • Organizer
      BioMecForum 第67回研究会
    • Place of Presentation
      吹田
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 循環器領域における生体システム学:シミュレーションの循環薬理学への応用

    • Author(s)
      芦原貴司
    • Organizer
      文部科学省戦略的大学連携支援事業:広域大学連携による「臨床医工学・情報学」高度人材育成システムの構築
    • Place of Presentation
      大阪
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] シミュレーション医学で不整脈治療メカニズムに迫る

    • Author(s)
      芦原貴司
    • Organizer
      第9回福島不整脈懇話会
    • Place of Presentation
      福島
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 心房細動の機序と治療に関する最近の話題

    • Author(s)
      芦原貴司
    • Organizer
      第5回京都日赤循環器フォーラム
    • Place of Presentation
      京都
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Book] 心不全をマスターする:病態を理解して治療できる医師になろう2013

    • Author(s)
      服部隆一編
    • Publisher
      文光堂
    • Related Report
      2012 Final Research Report
  • [Book] 服部隆一編:心不全をマスターする:病態を理解して治療できる医師になろう2013

    • Author(s)
      芦原貴司,堀江 稔
    • Publisher
      文光堂
    • Related Report
      2012 Annual Research Report
  • [Book] 池田隆徳,山下武志編著:不整脈概論:専門医になるためのエッセンシャルブック2013

    • Author(s)
      芦原貴司
    • Publisher
      メジカルビュー社
    • Related Report
      2012 Annual Research Report
  • [Book] 不整脈の実験モデル:不整脈のシミュレーション.不整脈学2012

    • Author(s)
      芦原貴司(分担)
    • Publisher
      南江堂
    • Related Report
      2012 Final Research Report
  • [Book] シミュレーション辞典2012

    • Author(s)
      日本シミュレーション学会編
    • Publisher
      コロナ社
    • Related Report
      2012 Final Research Report
  • [Book] 不整脈学2012

    • Author(s)
      芦原貴司
    • Publisher
      南江堂
    • Related Report
      2012 Annual Research Report
  • [Book] シミュレーション辞典2012

    • Author(s)
      芦原貴司, ほか(分担執筆)
    • Total Pages
      452
    • Publisher
      コロナ社
    • Related Report
      2011 Annual Research Report
  • [Book] 成り立ちから理解する心電図波形:心筋の活動電位を読み解く2012

    • Author(s)
      芦原貴司(分担執筆)
    • Total Pages
      211
    • Publisher
      秀潤社
    • Related Report
      2011 Annual Research Report
  • [Book] Cardiac Defibrillation - Mechanisms, Challenges and Implications2011

    • Author(s)
      Mechanisms of defibrillation failure. In Trayanova N (ed)
    • Publisher
      InTech
    • Related Report
      2012 Final Research Report
  • [Book] Cardiac Defibrillation-Mechanisms, Challenges and Implications2011

    • Author(s)
      Ashihara T, et al(分担執筆)
    • Total Pages
      248
    • Publisher
      InTech
    • Related Report
      2011 Annual Research Report
  • [Book] ステップアップのための不整脈診療ガイドブック2011

    • Author(s)
      芦原貴司(分担執筆)
    • Total Pages
      344
    • Publisher
      メジカルビュー社
    • Related Report
      2011 Annual Research Report
  • [Remarks]

    • URL

      http://square.umin.ac.jp/ash/vitae.html

    • Related Report
      2012 Final Research Report
  • [Remarks] Spiral in Cardiology

    • URL

      http://square.umin.ac.jp/ash/vitae.html

    • Related Report
      2012 Annual Research Report
  • [Remarks]

    • URL

      http://square.umin.ac.jp/ash/vitae.html

    • Related Report
      2011 Annual Research Report
  • [Remarks] 以下,参考までに,平成22年度の受賞歴を記す.第3回アジア太平洋不整脈学会(APHRS),2010/10/27-30,Best Paper Award/Clinical(第1位)を受賞

    • URL

      http://square.umin.ac.jp/ash/vitae.html

    • Related Report
      2010 Annual Research Report
  • [Remarks] 以下,参考までに,平成21年度の受賞歴を記す.第26回日本心電学会学術集会,2009/07/02-04,第14回日本心電学会学術奨励賞・最優秀賞を受賞.

    • URL

      http://square.umin.ac.jp/ash/vitae.html

    • Related Report
      2009 Annual Research Report

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Published: 2009-04-01   Modified: 2019-07-29  

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