The role of IQGAP1 in heart failure prevention

• Project/Area Number: 21790743
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Circulatory organs internal medicine
• Research Institution: Kitasato University
• Principal Investigator: TOJO Minako (TOJO YAMAOKA Minako) 北里大学, 医療衛生学部, 准教授 (80327345)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
• Keywords: 心不全 / 臓器保護 / 血管新生 / 予防医学 / 虚血再灌流

Research Abstract

We investigated the role of IQ motif-containing GTPase-activating protein 1(IQGAP1), a scaffold protein for growth factor signaling and production of reactive oxygen species, on cardiac remodeling in response to ischemic heart damage using heart derived culture cells. IQGAP1 may be an important modulator for heart failure prevention, especially in extra matrix cell growth of the heart.

Research Products

• [Journal Article] Usefulness of pet ownership as a modulator of cardiac autonomic imbalance in patients with diabetes mellitus, hypertension and/or hyperlipidemia (2012)
  • Author(s): Aiba N, Hotta K, Yokoyama M, Wang G, Tabata M, Kamiya K, Shimizu R, Kamekawa D, Hoshi K, Yamaoka-Tojo M, Masuda T
  • Journal Title: Am J Cardiol.2012 Jan 23 Volume: (Epub ahead of print)(In press) Issue: 8 Pages: 1164-1170
  • DOI: 10.1016/j.amjcard.2011.11.055
  • Peer Reviewed
• [Journal Article] 高齢虚血性心疾患患者の退院後の身体活動強度は下肢筋力だけでなくバランス機能の影響を受けている (2012)
  • Author(s): 根本慎司、松永篤彦、山本周平、亀川大輔、松沢良太、阿部義史、高橋佑太、林祐介、室内直樹、若梅一樹、木村雅彦、神谷健太郎、見井田和正、野田千春、東條美奈子、増田卓、和泉徹
  • Journal Title: 心臓リハビリテーション Volume: 17(In press)
  • Peer Reviewed
• [Journal Article] Pedometer-based exercise increases physical activity and improves endothelial function in patients at high risk of cardiova scular disease (2012)
  • Author(s): Wakaume K, Yamaoka-Tojo M, Nemoto S, Kameda R, Aiba N, Yoshida Y, Machida Y, Masuda T, Izumi T
  • Journal Title: 日循協予防学会誌 Volume: 47 Pages: 13-23
  • Peer Reviewed
• [Journal Article] 特集:高齢者の心不全,Seminar 4.高齢者心不全のリハビリテーションを考える (2012)
  • Author(s): 東條美奈子、神谷健太郎
  • Journal Title: 老年医学 Volume: 50 Pages: 33-37
• [Journal Article] Pleiotropic effects of ARB in vascular metabolism : focusing on atherosclerosis-based cardiovascular disease (2011)
  • Author(s): Honjo T, Yamaoka-Tojo M, Inoue N.
  • Journal Title: Curr Vasc Pharmacol Volume: 9(2) Pages: 145-52
  • Peer Reviewed
• [Journal Article] New concepts of angiotensin receptor blocker(ARB) in atherosclerosis : ARB as a metabolic-improving agent (2011)
  • Author(s): Yamaoka-Tojo M.
  • Journal Title: Curr Vasc Pharmacol Volume: 9(2) Pages: 128-128
• [Journal Article] Circulating interleukin-18 : a specific biomarker for atherosclerosis-prone patients with metabolic syndrome (2011)
  • Author(s): Yamaoka-Tojo M, Tojo T, Takahira N, Masuda T, Kameda R, Wakaume K, Izumi T.
  • Journal Title: Nutr Metab(Lond) Volume: 8 Pages: 3-3
  • Peer Reviewed
• [Journal Article] Vascular protective effects of ezetimibe : seeking possibilities of ezetimibe in vascular disease(editorial) (2011)
  • Author(s): Yamaoka-Tojo M.
  • Journal Title: Curr Vasc Pharmacol Volume: 9(1) Pages: 61-61
• [Journal Article] Ezetimibe and reactive oxygen species (2011)
  • Author(s): Yamaoka-Tojo M, Tojo T, Takahira N, Masuda T, Izumi T.
  • Journal Title: Curr Vasc Pharmacol Volume: 9(1) Pages: 109-20
  • Peer Reviewed
• [Journal Article] Circulating interleukin-18 : a specific biomarker for atherosclerosis-prone patients with metabolic syndrome (2011)
  • Author(s): Yamaoka-Tojo M, Tojo T, Takahira N, Masuda T, Kameda R, Wakaume K, Izumi T
  • Journal Title: Nutr Metab (Lond) Volume: 8 Issue: 1 Pages: 3-3
  • DOI: 10.1186/1743-7075-8-3
  • Peer Reviewed
• [Journal Article] Pleiotropic effects of ARB in vascular metabolism : focusing on atherosclerosis-based cardiovascular disease (2011)
  • Author(s): Honjo T, Yamaoka-Tojo M, Inoue N.
  • Journal Title: Curr Vase Pharmacol Volume: 9 Issue: 2 Pages: 145-152
  • DOI: 10.2174/157016111794519273
  • Peer Reviewed
• [Journal Article] New concepts of angiotensin receptor blocker (ARB) in atherosclerosis : ARB as a metabolic-improving agent (editorial) (2011)
  • Author(s): Yamaoka-Tojo M
  • Journal Title: Curr Vase Pharmacol Volume: 9 Issue: 2 Pages: 128-128
  • DOI: 10.2174/157016111794519282
• [Journal Article] Ezetimibe and reactive oxygen species (2011)
  • Author(s): Yamaoka-Tojo M, Tojo T, Takahira N, Masuda T, Izumi T
  • Journal Title: Curr Vasc Pharmacol Volume: 9 Issue: 1 Pages: 109-120
  • DOI: 10.2174/157016111793744652
  • Peer Reviewed
• [Journal Article] Vascular protective effects of ezetimibe : seeking possibilities of ezetimibe in vascular disease (editorial) (2011)
  • Author(s): Yamaoka-Tojo M
  • Journal Title: Curr Vasc Pharmacol Volume: 9 Issue: 1 Pages: 61-61
  • DOI: 10.2174/157016111793744689
• [Journal Article] トルバプタンにより難治性右心不全が改善した心アミロイドーシスの1例、Editorial Comment (2011)
  • Author(s): 東條美奈子
  • Journal Title: 心臓 Volume: 44 Pages: 354-355
• [Journal Article] Elevated circulating levels of an incretin hormone, glucagon-like peptide-1, are associated with metabolic components in high-risk patients with cardiovascular disease (2010)
  • Author(s): Yamaoka-Tojo M, Tojo T, Takahira N, Matsunaga A, Aoyama N, Masuda T, Izumi T.
  • Journal Title: Cardiovascular Diabetology Volume: 9 Pages: 17-17
  • Peer Reviewed
• [Journal Article] Elevated circulating levels of an incretin hormone, glucagon-like peptide-1, are associated with metabolic components in high-risk patients with cardiovascular disease. (2010)
  • Author(s): Yamaoka-Tojo M, Tojo T, et al.
  • Journal Title: Cardiovascular Diabetology. Volume: 9 Pages: 17-17
  • Peer Reviewed
• [Journal Article] Effects of ezetimibe add-on therapy for high-risk patients with dyslipidemia (2009)
  • Author(s): Yamaoka-Tojo M, Tojo T, Kosugi R, Hatakeyama Y, Yoshida Y, Machida Y, Aoyama N, Masuda T, Izumi T.
  • Journal Title: Lipids in Health and Disease Volume: 8 Pages: 41-41
• [Journal Article] Effects of ezetimibe add-on therapy for high-risk patients with dyslipidemia. (2009)
  • Author(s): Yamaoka-Tojo M, Tojo T, Kosugi R, Hatakeyama Y, Yoshida Y, Machida Y, Aoyama N, Masuda T, Izumi T. Yamaoka Tojo M, Tojo T, Masuda T, Izumi T.
  • Journal Title: Lipids in Health and Disease. 8:41 Pages: 1-8
  • Peer Reviewed
• [Journal Article] Circulating interleukin-18 : a specific biomarker for atherosclerosis-prone patients with metabolic syndrome.
  • Author(s): Yamaoka-Tojo M, Tojo T, et al.
  • Journal Title: Nutr Metab (Lond). Volume: (2011 Jan 20.[Epub ahead of print])
  • Peer Reviewed
• [Journal Article] Pleiotropic effects of ARB in vascular metabolism : focusing on atherosclerosis-based cardiovascular disease.
  • Author(s): Honjo T, Yamaoka-Tojo M, Inoue N.
  • Journal Title: Curr Vasc Pharmacol. Volume: (2010 Dec 14.[Epub ahead of print])
  • Peer Reviewed
• [Journal Article] New concepts of angiotensin receptor blocker (ARB) in atherosclerosis : ARB as a metabolic-improving agent.
  • Author(s): Yamaoka-Tojo M.
  • Journal Title: Curr Vasc Pharmacol. Volume: (2010 Dec 14.[Epub ahead of print])
  • Peer Reviewed
• [Journal Article] Ezetimibe and reactive oxygen species.
  • Author(s): Yamaoka-Tojo M, Tojo T, et al.
  • Journal Title: Curr Vasc Pharmacol. Volume: (2010 Nov 2.[Epub ahead of print])
  • Peer Reviewed
• [Journal Article] Vascular protective effects of ezetimibe : seeking possibilities of ezetimibe in vascular disease
  • Author(s): Yamaoka-Tojo M.
  • Journal Title: Curr Vasc Pharmacol. Volume: (2010 Nov 2.[Epub ahead of print])
  • Peer Reviewed
• [Journal Article] Pleiotropic effects of ARB in vascular metabolism : focusing on ather osclerosis-based cardiovascular disease.
  • Author(s): Honjo T, Yamaoka-Tojo M, Inoue N.
  • Journal Title: Curr Vasc Pharmacol (in press)
  • Peer Reviewed
• [Journal Article] New concepts of angiotensin receptor blocker (ARB) in atherosclerosis : ARB as a metabolic-imnrovine agent
  • Author(s): Yamaoka Tojo M, Tojo T.
  • Journal Title: Cun Vasc Phannacol (in press)
  • Peer Reviewed
• [Journal Article] Ezetimibe and reactive oxygen species.
  • Author(s): Yamaoka Tojo M, Tojo T, Masuda T, Izumi T.
  • Journal Title: Curr Vasc Pharmacol (in press)
  • Peer Reviewed
• [Journal Article] Vascular protective effects of ezetimibe : seeking possibilities of ezetimibe in vascular disease
  • Author(s): Yamaoka Tojo M, Tojo T.
  • Journal Title: Curr Vasc Pharmacol (in press)
  • Peer Reviewed
• [Presentation] Salusin-is a novel diagnostic biomarker of neutrally mediated syncope (2012)
  • Author(s): Kameda R, Yamaoka-Tojo M, Tojo T, Wakaume K, Nemoto S, Kitasato L, Shichiri M, Izumi T.
  • Organizer: The 76th Annual Scientific Meeting of the Japanese Circulation Society
  • Place of Presentation: Fukuoka
  • Year and Date: 2012-03-17
• [Presentation] 採気体操が健常高齢者の心血管呼吸応答と自律神経活動に及ぼす影響について (2012)
  • Author(s): 原美弥子、堀田一樹、饗庭尚子、小倉彩、清水良祐、亀川大輔、秋山綾子、神谷健太郎、東條美奈子、松永篤彦、増田卓
  • Organizer: The 76^<th> Annual Scientific Meeting of the Japanese Circulation Society (JCS2012)
  • Place of Presentation: 福岡インターナショナル会議センター(福岡)
  • Year and Date: 2012-03-17
• [Presentation] Salusin-β is a novel diagnostic biomarker of neutrally mediated syncope (2012)
  • Author(s): Kameda R, Yamaoka-Tojo M, Tojo T, Wakaume K, Nemoto S, Kitasato L, Shichiri M, Izumi T
  • Organizer: The 76^<th> Annual Scientific Meeting of the Japanese Circulation Society (JCS2012)
  • Place of Presentation: 福岡インターナショナル会議センター(福岡)
  • Year and Date: 2012-03-17
• [Presentation] 生活習慣病患者における身体活動量の増加は可溶性Fms様チロシンキナーゼ-1を増加させる (2012)
  • Author(s): 牧野彰宏、東條美奈子、根本慎司、若梅一樹、亀田良、遠原真一、高橋由美、松永篤彦、増田卓、和泉徹
  • Organizer: The 76th Annual Scientific Meeting of the Japanese Circulation Society
  • Place of Presentation: Fukuoka
  • Year and Date: 2012-03-16
• [Presentation] Effects of increasing physical activity on circulating levels of Tenascin-C in high risk patients with atherosclerosis (2012)
  • Author(s): Kitasato L, Yamaoka-Tojo M, Kameda R, Wakaume K, Nemoto S, Shimohama T, Tojo T, Izumi T.
  • Organizer: The 76th Annual Scientific Meeting of the Japanese Circulation Society
  • Place of Presentation: Fukuoka
  • Year and Date: 2012-03-16
• [Presentation] 生活習慣病患者における身体活動量の増加は可溶性Fms様チロシンキナーゼ-1を増加させる (2012)
  • Author(s): 牧野彰宏、東條美奈子、根本慎司、若梅一樹、亀田良、遠原真一、高橋由美、松永篤彦、増田卓、和泉徹
  • Organizer: The 76^<th> Annual Scientific Meeting of the Japanese Circulation Society (JCS2012)
  • Place of Presentation: 福岡インターナショナル会議センター(福岡)
  • Year and Date: 2012-03-16
• [Presentation] Effects of increasing physical activity on circulating levels of Tenascin-C in high risk patients with atherosclerosis (2012)
  • Author(s): Kitasato L, Yamaoka-Tojo M, Kameda R, Wakaume K, Nemoto S, Shimohama T, Tojo T, Izumi T
  • Organizer: The 76^<th> Annual Scientific Meeting of the Japanese Circulation Society (JCS2012)
  • Place of Presentation: 福岡インターナショナル会議センター(福岡)
  • Year and Date: 2012-03-16
• [Presentation] エゼチミブに期待する抗動脈硬化作用と心血管病予防 (2011)
  • Author(s): 東條美奈子
  • Organizer: 第15回日本心血管内分泌代謝学会学術総会ランチョンセミナー2
  • Place of Presentation: 千里ライフサイエンスセンター(大阪)(招待講演)
  • Year and Date: 2011-11-25
• [Presentation] Soluble Fms-Like Tyrosine Kinase 1 is a novel predictor of cardiovascular disease progression in patients with coronary artery disease (2011)
  • Author(s): Kameda R, Yamaoka-Tojo M, Tojo T, Wakaume K, Nemoto S, Kitasato L, Yoshida Y, Shimohama T, Machida Y, Izumi T.
  • Place of Presentation: USA
  • Year and Date: 2011-11-15
• [Presentation] Soluble Fms-Like Tyrosine Kinase 1 is a novel predictor of cardiovascular disease progression in patients with coronary artery disease (11051/2023) (2011)
  • Author(s): Kameda R, Yamaoka-Tojo M, Tojo T, Wakaume K, Nemoto S, Kitasato L, Yoshida Y, Shimohama T, Machida Y, Izumi T
  • Organizer: 米国心臓病学会(AHA2011)
  • Place of Presentation: Orland, FL, USA
  • Year and Date: 2011-11-15
• [Presentation] Effects of serum eicosapentaemoic acid on vascular inflammation and endothelial dysfunction in Japanese hemodialysis patients (2011)
  • Author(s): Kamada Y, Kamekawa D, Kamiya K, Shimizu R, Matsunaga A, Akiyama A, Ogura M, Yamaoka-Tojo M, Masuda T, Izumi T.
  • Place of Presentation: USA
  • Year and Date: 2011-11-14
• [Presentation] Reducing the risks of heart failure. (2011)
  • Author(s): Yamaoka-Tojo M.
  • Organizer: Symposium 13, The 15th Annual Scientific Meeting of Japanese Heart Failure Society
  • Place of Presentation: Kagoshima, Japan
  • Year and Date: 2011-10-15
• [Presentation] Reducing the risks of heart failure. Symposium 13 (2011)
  • Author(s): Yamaoka-Tojo M
  • Organizer: The 15th Annual Scientific Meeting of Japanese Heart Failure Society
  • Place of Presentation: かごしま県民交流センター(鹿児島)(招待講演)
  • Year and Date: 2011-10-15
• [Presentation] 動脈硬化性疾患ハイリスクとしてのメタボリックシンドローム・CKDとその管理「心不全予防のためのアプローチ:動脈硬化性疾患患者のための包括的疾病管理」 (2011)
  • Author(s): 東條美奈子
  • Organizer: 第15回日本心不全学会学術集会ランチョン教育セミナー7
  • Place of Presentation: かごしま県民交流センター(鹿児島)(招待講演)
  • Year and Date: 2011-10-14
• [Presentation] Association between Pentraxin 3 and renal function in patients at high risk of cardiovascular disease (2011)
  • Author(s): Kameda R, Yamaoka-Tojo M, Tojo T, Wakaume K, Nemoto S, Kitasato L, Yoshida Y, Hatakeyama Y, Machida Y, Izumi T.
  • Organizer: The 15th Annual Scientific Meeting of Japanese Heart Failure Society
  • Place of Presentation: Kagoshima, Japan
  • Year and Date: 2011-10-13
• [Presentation] Association between Pentraxin 3 and renal function in patients at high risk of cardiovascular disease (2011)
  • Author(s): Kameda R, Yamaoka-Tojo M, Tojo T, Wakaume K, Nemoto S, Kitasato L, Yoshida Y, Hatakeyama Y, Machida Y, Izumi T.
  • Organizer: The 15th Annual Scientific Meeting of Japanese Heart Failure Society
  • Place of Presentation: かごしま県民交流センター(鹿児島)
  • Year and Date: 2011-10-13
• [Presentation] Functional arterial stiffness predicts a thickening of carotid intima-media one year later in patients with lifestyle-related disease (2011)
  • Author(s): Ogura NM, Kamekawa D, Kamiya K, Matsunaga A, Kimura M, Shimizu R, Ogura T, Noda C, Yamaoka-Tojo M, Masuda T.
  • Organizer: ESC 2011
  • Place of Presentation: Paris, France
  • Year and Date: 2011-08-30
• [Presentation] Functional arterial stiffness predicts a thickening of carotid intima-media one year later in patients with lifestyle-related disease (2011)
  • Author(s): Ogura NM, Kamekawa D, Kamiya K, Matsunaga A, Kimura M, Shimizu R, Ogura T, Noda C, Yamaoka-Tojo M, Masuda T
  • Organizer: 欧州心臓病学会(ESC2011)
  • Place of Presentation: Paris, France
  • Year and Date: 2011-08-30
• [Presentation] Quadriceps strength and balance function necessary to accomplish at least 300 meters in a six-minute walk distance in patients with ischemic heart disease (2011)
  • Author(s): Kamiya K, Masuda T, Miida K, Matsunaga A, Ogura MN, Kimura M, Noda C, Yamaoka-Tojo M, Izumi T.
  • Organizer: ESC 2011
  • Place of Presentation: Paris, France
  • Year and Date: 2011-08-29
• [Presentation] Increased physical activity decreases circulating pentraxin 3 levels in patients at high risk of cardiovascular disease (2011)
  • Author(s): Wakaume K, Yamaoka-Tojo M, Nemoto S, Kameda R, Aiba N, Tojo T, Yoshida Y, Machida Y, Masuda T, Izumi T.
  • Organizer: ESC 2011
  • Place of Presentation: Paris, France
  • Year and Date: 2011-08-29
• [Presentation] The plasma levels of B-type natriuretic peptide is a useful predictor of cardiac events for out-clinic patients with asymptomatic heart failure who are in stable condition (2011)
  • Author(s): Yamaoka-Tojo M, Kitasato L, Nemoto S, Wakaume K, Kameda R, Yoshida Y, Machida Y, Tojo T, Kasuda T, Izumi T.
  • Organizer: ESC 2011
  • Place of Presentation: Paris, France
  • Year and Date: 2011-08-29
• [Presentation] Quadriceps strength and balance function necessary to accomplish at least 300 meters in a six-minute walk distance in patients with ischemic heart disease (2011)
  • Author(s): Kamiya K, Masuda T, Miida K, Matsunaga A, Ogura MN, Kimura M, Noda C, Yamaoka-Tojo M, Izumi T
  • Organizer: 欧州心臓病学会(ESC2011)
  • Place of Presentation: Paris, France
  • Year and Date: 2011-08-29
• [Presentation] Increased physical activity decreases circulating pentraxin 3 levels in patients at high risk of cardiovascular disease (2011)
  • Author(s): Wakaume K, Yamaoka-Tojo M, Nemoto S, Kameda R, Aiba N, Tojo T, Yoshida Y, Machida Y, Masuda T, Izumi T
  • Organizer: 欧州心臓病学会(ESC2011)
  • Place of Presentation: Paris, France
  • Year and Date: 2011-08-29
• [Presentation] The plasma levels of B-type natriuretic peptide is a useful predictor of cardiac events for out-clinic patients with asympt omatic heart failure who are in stable condition (2011)
  • Author(s): Yamaoka-Tojo M, Kitasato L, Nemoto S, Wakaume K, Kameda R, Yoshida Y, Machida Y, Tojo T, Kasuda T, Izumi T
  • Organizer: 欧州心臓病学会(ESC2011)
  • Place of Presentation: Paris, France
  • Year and Date: 2011-08-29
• [Presentation] BNPモーニングセミナー「BNPを用いた心疾患の二次予防」 (2011)
  • Author(s): 東條美奈子
  • Organizer: 第75回日本循環器学会総会・学術集会
  • Place of Presentation: パシフィコ横浜(横浜)(招待講演)
  • Year and Date: 2011-08-04
• [Presentation] ガイドラインに基づく疾病管理を受けている維持期虚血性心疾患患者の運動習慣が血清脂質および動脈硬化指標に与える影響 (2011)
  • Author(s): 根本慎司、東條美奈子、若梅一樹、山本周平、亀田良、畠山祐子、町田陽二、吉田友紀、松永篤彦、増田卓、和泉徹
  • Organizer: 第75回日本循環器学会総会・学術集会
  • Place of Presentation: パシフィコ横浜(横浜)(e-poster)
  • Year and Date: 2011-08-04
• [Presentation] The change of circulating interleukin-18 is associated with the change of arteriosclerosis, a 5-year observational study from Kitasato Registry of Cardiovascular Disease Prevention (2011)
  • Author(s): Kameda R, Yamaoka-Tojo M, Wakaume K, Tojo T, Aiba N, Yoshida Y, Machida Y, Matsimaga A, Masuda T, Izumi T
  • Organizer: 第75回日本循環器学会総会・学術集会
  • Place of Presentation: パシフィコ横浜(横浜)(e-poster)
  • Year and Date: 2011-08-04
• [Presentation] 急性心筋梗塞患者の呼吸機能は低下しており、入院期の6分間歩行距離に影響を及ぼしている (2011)
  • Author(s): 林祐介、木村雅彦、松永篤彦、小林主献、高橋祐太、堀田一樹、山本周平、根本慎司、神谷健太郎、見井田和正、遠原真一、高橋由美、河野真理、倉島真紀、横山美佐子、野田千春、東條美奈子、増田卓、和泉徹
  • Organizer: 第17回日本心臓リハビリテーション学会
  • Place of Presentation: 大阪国際会議場(大阪)
  • Year and Date: 2011-07-17
• [Presentation] 生活習慣病患者において身体活動量を増加させる運動指導は4週間でも血中Pentraxin3を低下させる (2011)
  • Author(s): 若梅一樹、東條美奈子、根本慎司、亀田良、饗庭尚子、東條大輝、吉田友紀、町田陽二、野田千春、増田卓、和泉徹
  • Organizer: 第17回日本心臓リハビリテーション学会
  • Place of Presentation: 大阪国際会議場(大阪)
  • Year and Date: 2011-07-16
• [Presentation] 安定期虚血性心疾患患者の血管内皮機能は中強度の身体活動時間の増加量に応じて改善する (2011)
  • Author(s): 根本慎司、東條美奈子、松永篤彦、和泉徹
  • Organizer: 第17回日本心臓リハビリテーション学会
  • Place of Presentation: 大阪国際会議場(大阪)
  • Year and Date: 2011-07-16
• [Presentation] 椅子座位ヨガエクササイズが入院期心筋梗塞患者の自律神経活動と心血管応答に及ぼす影響について (2011)
  • Author(s): 秋山綾子、増田卓、亀川大輔、堀田一樹、清水良祐、饗庭尚子、田畑稔、小倉彩、横山美佐子、神谷健太郎、見井田正和、高橋由美、野田千春、東條美奈子、和泉徹
  • Organizer: 第17回日本心臓リハビリテーション学会
  • Place of Presentation: 大阪国際会議場(大阪)
  • Year and Date: 2011-07-16
• [Presentation] 左室拡張障害による心不全患者の運動機能は左室収縮能の低下による心不全患者と同等に低下する (2011)
  • Author(s): 神谷健太郎、増田卓、見井田和正、河野真理、高橋由美、倉島真紀、小倉彩、木村雅彦、野田千春、東條美奈子、猪又孝元、松永篤彦、和泉徹
  • Organizer: 第17回日本心臓リハビリテーション学会
  • Place of Presentation: 大阪国際会議場(大阪)
  • Year and Date: 2011-07-16
• [Presentation] 冠動脈疾患およびその高リスク患者において、血中Pentraxin 3(PTX3)濃度はLDL/HDL比と関連する (2011)
  • Author(s): 亀田良、東條美奈子、若梅一樹、北里梨紗、吉田友紀、東條大輝、町田陽二、饗庭尚子、松永篤彦、増田卓、和泉徹
  • Organizer: 第47回日本循環器病予防学会・日本循環器管理研究協議会総会
  • Place of Presentation: 福岡
  • Year and Date: 2011-06-04
• [Presentation] 冠動脈疾患およびその高リスク患者において、血中Pentraxin3(PTX3)濃度はLDL/HDL比と関連する (2011)
  • Author(s): 亀田良、東條美奈子、若梅一樹、北亜梨紗、吉田友紀、東條大輝、町田陽二、饗庭尚子、松永篤彦、増田卓、和泉徹
  • Organizer: 第47回日本循環器病予防学会・日本循環器管理研究協議会総会
  • Place of Presentation: パピヨン24ガスホール(福岡)
  • Year and Date: 2011-06-04
• [Presentation] 歩数計を利用したセルフモニタリングによる運動指導は身体活動量を増加させ血管内皮機能の改善につながる (2011)
  • Author(s): 若梅一樹、東條美奈子、根本慎司、亀田良、饗庭尚子、吉田友紀、町田陽二、増田卓、和泉徹
  • Organizer: 第47回日本循環器病予防学会・日本循環器管理研究協議会総会
  • Place of Presentation: 福岡
  • Year and Date: 2011-06-03
• [Presentation] 北里大学東病院心臓二次予防センターが推進する地域医療連携を活用した疾病管理システムの役割と効果 (2011)
  • Author(s): 町田陽二、吉田友紀、東條美奈子、上野勉、谷明日美、斉藤史郎、佐藤敏彦、和泉幸代、山下智、和泉徹
  • Organizer: 第47回日本循環器病予防学会・日本循環器管理研究協議会総会
  • Place of Presentation: 福岡
  • Year and Date: 2011-06-03
• [Presentation] 歩数計を利用したセルフモニタリングによる運動指導は身体活動量を増加させ血管内皮機能の改善につながる (2011)
  • Author(s): 若梅一樹、東條美奈子、根本慎司、亀田良、饗庭尚子、吉田友紀、町田陽二、増田卓、和泉徹
  • Organizer: 第47回日本循環器病予防学会・日本循環器管理研究協議会総会
  • Place of Presentation: パピヨン24ガスホール(福岡)(日本循環器病予防学会YIA優秀賞受賞)
  • Year and Date: 2011-06-03
• [Presentation] 北里大学東病院心臓二次予防センターが推進する地域医療連携を活用した疾病管理システムの役割と効果 (2011)
  • Author(s): 町田陽二、吉田友紀、東條美奈子、上野勉、谷明日美、斉藤史郎、佐藤敏彦、和泉幸代、山下智、和泉徹
  • Organizer: 第47回日本循環器病予防学会・日本循環器管理研究協議会総会
  • Place of Presentation: パピヨン24ガスホール(福岡)
  • Year and Date: 2011-06-03
• [Presentation] Regular physical activity prevents atherosclerosis in high-risk patients with cardiovascular disease (2011)
  • Author(s): Nemoto S, Yamaoka-Tojo M, Wakaume K, Yamamoto S, Kimura M, Ogura M, Aiba N, Kameda R, Machida Y, Yoshida Y, Matsunaga A, Masuda T, Izumi T.
  • Organizer: American College of Sports Medicine
  • Place of Presentation: Denver, CO, USA
  • Year and Date: 2011-05-31
• [Presentation] Regular physical activity prevents atherosclerosis in high-risk patients with cardiovascular disease (2011)
  • Author(s): Nemoto S, Yamaoka-Tojo M, Wakaume K, Yamamoto S, Kimura M, Ogura M, Aiba N, Kameda R, Machida Y, Yoshida Y, Matsunaga A, Masuda T, Izumi T
  • Organizer: 米国スポーツ医学会(American College of Sports Medicine ; ACSM)
  • Place of Presentation: Denver, CO, USA
  • Year and Date: 2011-05-31
• [Presentation] アフタヌーンセミナー「心血管病予防のためのアンチエイジング」 (2011)
  • Author(s): 東條美奈子
  • Organizer: 第11回日本抗加齢医学会総会
  • Place of Presentation: 国立京都国際会館(京都)(招待講演)
  • Year and Date: 2011-05-28
• [Presentation] ガイドラインに基づく疾病管理を受けている維持期虚血性心疾患患者の運動習慣が血清脂質および動脈硬化指標に与える影響 (2011)
  • Author(s): 根本慎司、東條美奈子、若梅一樹、山本周平、亀田良、畠山祐子、町田陽二、吉田友紀、松永篤彦、増田卓、和泉徹
  • Organizer: 第75回日本循環器学会総会・学術集会
  • Place of Presentation: 横浜
  • Year and Date: 2011-03-19
• [Presentation] BNPを用いた心疾患の二次予防 (2011)
  • Author(s): 東條美奈子
  • Organizer: 第75回日本循環器学会総会・学術集会BNPランチョンセミナー
  • Place of Presentation: パシフィコ横浜(横浜)
  • Year and Date: 2011-03-19
• [Presentation] ガイドラインに基づく疾病管理を受けている維持期虚血性心疾患患者の運動習慣が血清脂質および動脈硬化指標に与える影響 (2011)
  • Author(s): 根本慎司、東條美奈子, ほか
  • Organizer: 第75回日本循環器学会総会・学術集会
  • Place of Presentation: パシフィコ横浜(横浜)
  • Year and Date: 2011-03-19
• [Presentation] The change of circulating interleukin-18 are associated with the change of arteriosclerosis, a 5-year observational study from Kitasato Registry of Cardiovascular Disease Prevention. (2011)
  • Author(s): Kameda R, Yamaoka-Tojo M, Wakaume K, Tojo T, et al.
  • Organizer: The 75^<th> Annual Scientific Meeting of the Japanese Circulation Society(日本循環器学会総会・学術集会)
  • Place of Presentation: パシフィコ横浜(横浜)
  • Year and Date: 2011-03-19
• [Presentation] The change of circulating interleukin-18 is associated with the change of arteriosclerosis, a 5-year observational study from Kitasato Registry of Cardiovascular Disease Prevention (2011)
  • Author(s): Kameda R, Yamaoka-Tojo M, Wakaume K, Tojo T, Aiba N, Yoshida Y, Machida Y, Matsunaga A, Masuda T, Izumi T.
  • Organizer: The 75th Annual Scientific Meeting of the Japanese Circulation Society
  • Place of Presentation: Yokohama
• [Presentation] Lifestyle modification-improving systemic athero-protective factor, circulating pentraxin 3, in high-risk patients with metabolic syndrome (2010)
  • Author(s): Yamaoka-Tojo M, Tojo T, Wakaume K, Kameda R, Takahira N, Aoyama N, Matsunaga A, Masuda T, Izumi T.
  • Organizer: AHA2010
  • Place of Presentation: Chicago, IL, USA
  • Year and Date: 2010-11-15
• [Presentation] Decreased strength of quadriceps increases the risk of mortality in patients with chronic heart failure (2010)
  • Author(s): Kamiya K, Masuda T, Matsunaga A, Miida K, Ogura MN, Kimura M, Noda C, Yamaoka-Tojo M, Inomata T, Izumi T.
  • Organizer: AHA2010
  • Place of Presentation: Chicago, IL, USA
  • Year and Date: 2010-11-15
• [Presentation] Lifestyle modification-improving systemic athero-protective factor, circulating pentraxin 3, in high-risk patients with metabolic syndrome. (2010)
  • Author(s): Yamaoka-Tojo M, Tojo T, et al.
  • Organizer: 米国心臓病協会学術集会(AHA 2010)
  • Place of Presentation: Chicago, IL, USA
  • Year and Date: 2010-11-15
• [Presentation] Decreased strength of quadriceps increases the risk of mortality in patients with chronic heart failure. (2010)
  • Author(s): Kamiya K, Masuda T, Matsunaga A, Miida K, Ogura MN, Kimura M, Noda C, Yamaoka-Tojo M., et al.
  • Organizer: 米国心臓病協会学術集会(AHA 2010)
  • Place of Presentation: Chicago, IL, USA
  • Year and Date: 2010-11-15
• [Presentation] Anti-inflammatory effects of pentraxin 3 in human visceral adipocytes by reducing reactive oxygen species production (2010)
  • Author(s): Yamaoka-Tojo M, Tojo T, Takahira N, Aoyama N, Masuda T, Izumi T.
  • Organizer: ESC2010
  • Place of Presentation: Stockholm, Sweden
  • Year and Date: 2010-08-30
• [Presentation] Anti-inflammatory effects of pentraxin 3 in human visceral adipocytes by reducing reactive oxygen species production. (2010)
  • Author(s): Yamaoka-Tojo M, Tojo T, et al.
  • Organizer: 欧州心臓病学会学術集会(ESC 2010)
  • Place of Presentation: Stockholm, Sweden
  • Year and Date: 2010-08-30
• [Presentation] Elevated circulating levels of glucose-like peptide-a are associated with metabolic risk factors in high-risk patients for cardiovascular disease. (2010)
  • Author(s): Yamaoka-Tojo M, Tojo T, Kosugi R, Aoyama N, Masuda T, Izumi T.
  • Organizer: The 74^<th> Annual Scientific Meeting of the Japanese Circulation Society(日本循環器学会総会)
  • Place of Presentation: Kyoto, Japan
  • Year and Date: 2010-03-06
• [Presentation] 糖尿病を合併した高血圧患者の糖・脂質代謝及び腎機能に対するL型およびN型のカルシウムチャネルブロッカーの効果-L型カルシウムチャネルブロッカーとの比較. (2009)
  • Author(s): 増田卓, 小倉彩, 山本壱弥, 鈴木秀俊, 清水良祐, 亀川大輔, 饗庭尚子, 田畑稔, 小松麻美, 横山美佐子, 野田千春, 東條美奈子, 和泉徹.
  • Organizer: 第32回日本高血圧症学会
  • Place of Presentation: 滋賀
  • Year and Date: 2009-10-02
• [Presentation] メタボリックシンドロームを合併した腹部肥満症例におけるコレスチミド併用ライフスタイル改善療法を用いた腹囲減少効果について (2009)
  • Author(s): 東條美奈子, 東條大輝, 小杉理恵, 畠山祐子, 青山直善, 増田卓, 和泉徹
  • Organizer: 第2回日本肥満症治療学会学術集会
  • Place of Presentation: 東京
  • Year and Date: 2009-07-10
• [Presentation] 心血管病の再発予防を目指した地域医療連携ネットワークの構築と課題 (2009)
  • Author(s): 町田陽二, 東條美奈子, 山下智, 川合由河, 和泉徹
  • Organizer: 第45回日本循環器病予防学会・日本循環器管理研究協議会総会
  • Place of Presentation: 横浜
  • Year and Date: 2009-06-05
• [Presentation] ライフスタイル改善により、減量に成功したメタボリックシンドローム症例では血清インターロイキン18濃度が低下する (2009)
  • Author(s): 東條美奈子, 東條大輝, 小杉理恵, 畠山祐子, 青山直善, 和泉徹
  • Organizer: 第45回日本循環器病予防学会・日本循環器管理研究協議会総会
  • Place of Presentation: 横浜
  • Year and Date: 2009-06-05
• [Presentation] 多疾患有病者とする心血管病患者への疾病管理 (2009)
  • Author(s): 町田陽二, 東條美奈子, 山下智, 川合由河, 和泉徹
  • Organizer: 第45回日本循環器病予防学会・日本循環器管理研究協議会総会
  • Place of Presentation: 横浜
  • Year and Date: 2009-06-05
• [Book] エビデンスにもとづく循環器病予防医学 (2012)
  • Author(s): 東條美奈子
  • Total Pages: 417
  • Publisher: 南山堂
• [Book] 疾病管理としての循環器予防医学、11肥満エビデンスにもとづく循環器病予防医学(東條美奈子ら編集) (2012)
  • Author(s): 東條美奈子、東條大輝
  • Publisher: 南山堂
• [Book] 循環器疾患における性差医療,総論3.女性循環器医の現状と問題点,成人病と生活習慣病,39巻10号(2009年10月号) (2009)
  • Author(s): 東條美奈子
  • Publisher: 東京医学社
• [Book] 循環器疾患の再発予防・重症化予防(特集循環器疾患と地域連携),呼吸と循環57(1) (2009)
  • Author(s): 町田陽二, 東條美奈子, 和泉徹
  • Publisher: 医学書院
• [Book] 見直されたレジン,10.レジンの幅広い使い方,Bメタボリックシンドローム,2)症例から見た食事・運動の強化とレジン (2009)
  • Author(s): 東條美奈子、和泉徹
  • Publisher: フジメディカル出版
• [Remarks]
  • URL: http://www.med.kitasato-u.ac.jp/~med_2/top/
• [Remarks]
  • URL: http://103lab.web.fc2.com/main.html
• [Remarks]
  • URL: http://1031ab.web.fc2.com/main.html