Phenotyping Patients With Obstructive Sleep Apnea and Treatment Strategy. an adoption of non-linear analysis-
| Project/Area Number |
21790781
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Respiratory organ internal medicine
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| Research Institution | Nara Medical University |
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Principal Investigator |
YAMAUCHI Motoo 奈良県立医科大学, 医学部, 助教 (30405378)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 睡眠時無呼吸症候群 / 非線形解析 / 呼吸制御システム / 持続陽圧呼吸(CPAP)療法 / CPAPアドヒアランス |
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| Research Abstract |
We analyzed the respiratory time series data during wakefulness in patients with obstructive sleep apnea(OSA). Breathing irregularity evaluated by both linear and non-linear analyses in patients with mixed apnea dominant OSA was significantly greater than in patients with obstructive apnea dominant, and was similar to central sleep apnea syndrome. Moreover, breathing irregularity was a predictive marker for CPAP adherence in patients with OSA. Thus we conclude that breathing irregularity during wakefulness evaluated by both linear and non-linear analyses reflects not only an OSAS phenotype but CPAP adherence.
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Report
(4 results)
Research Products
(24 results)
