| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Research Abstract |
In the present study, we demonstrated that one of toll like receptors, TLR8-mediated neutrophilic responses were markedly potentiated via NF-κB signaling by oxidative stress which is important in the pathophysiology of COPD. This might potentiate the neutrophilic inflammation during the viral-induced COPD exacerbations.
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