Research Project
Grant-in-Aid for Young Scientists (B)
Parkinson's disease is the second most common neurodegenerative disorder. Motor deficits which are result of nigral cell death are main feature of Parkinson's disease, but it is unclear the pathomechanisms of selective neuronal loss in substantia nigra. Previous studies revealed alpha-synuclein plays important role in molecular basis of Parkinson's disease. This study figure out that intracellular dopamine facilitates the toxicity of alpha-synuclein
All 2011 2010 2009 Other
All Journal Article (12 results) (of which Peer Reviewed: 8 results) Presentation (16 results) Remarks (2 results)
Mov Disord. 26巻
Pages: 621-628
Movement Disorders
Volume: 22 Pages: 621-628
Neurochem Int. 57巻
Pages: 857-866
Brain. 133巻
Pages: 1772-1778
J Neurol Sci. 289巻
Pages: 36-39
Clinical Neuroscience 28巻
Pages: 771-773
Neurochemistry International
Volume: 57 Pages: 857-866
Brain
Volume: 133 Pages: 1772-1778
Clinical Neuroscience
Volume: 28 Pages: 771-773
PD Today
Volume: 30 Pages: 14-15
Volume: 32 Pages: 14-15
J Neurol Sci 289
http://www.neurol.med.tohoku.ac.jp/