| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Research Abstract |
By using proteomic analysis, we searched for the immune target of Acute Inflammatory Demyelinating Polyneuropathy (AIDP). The target was considered to be the protein on the surface of the Schwann cell. We extract proteins from Schwannoma cell line, and we searched for the protein which reacted with the antibody (IgG) of the patients by 2 dimensional electrophoresis and western blotting. The proteins were identified with mass spectrometer. In the result, 3 proteins were thought to be the possible targets, and we found the autoantibodies against these proteins in the sera of the patients.
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