Research Project
Grant-in-Aid for Young Scientists (B)
Diabetes is a risk factor for atherosclerosis and the prevention of atherosclerosis is very important. We investigated the effects of GLP-1 receptor agonists (Ex-4) on vascular smooth muscle cells. Ex-4 attenuated neointimal formation after wire injury in mice. We demonstrated that the decrease in smooth muscle cell proliferation with Ex-4 may contribute the prevention of atherosclerosis. These unique effects of GLP-1R agonist may help design new therapies for cardiovascular disease in patients with type 2 diabetes.
All 2011 2010
All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (1 results)
Biochem Biophys Res Commun. 405
Pages: 79-84
Biochem Biophys Res Commun
Volume: (印刷中)
Diabetes
Volume: 59(4) Pages: 1030-1037