The effect of all-trans retinoic acid on FGF23 expression/secretion in human osteoblasts

Research Project

Project/Area Number	21790967
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Pediatrics
Research Institution	Tohoku University
Principal Investigator	HAKODA Akiko Tohoku University, 病院, 医員 (70509398)
Project Period (FY)	2009 – 2010
Project Status	Completed (Fiscal Year 2010)
Budget Amount *help	¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000) Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000) Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords	小児内分泌学 / 骨芽細胞 / レチノイン酸 / FGF23
Research Abstract	It remains unknown effects of all-trans retinoic acid (ATRA) on FGF23 expression/secretion in bone tissue. I therefore examined those effects using supernatants, mRNA and protein from human osteoblast culture. However, I couldn't observe the alteration of expression/secretion because FGF23 was not expressed in human osteoblasts we used.

Report

(3 results)