The effect of all-trans retinoic acid on FGF23 expression/secretion in human osteoblasts
| Project/Area Number |
21790967
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Pediatrics
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| Research Institution | Tohoku University |
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Principal Investigator |
HAKODA Akiko Tohoku University, 病院, 医員 (70509398)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 小児内分泌学 / 骨芽細胞 / レチノイン酸 / FGF23 |
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| Research Abstract |
It remains unknown effects of all-trans retinoic acid (ATRA) on FGF23 expression/secretion in bone tissue. I therefore examined those effects using supernatants, mRNA and protein from human osteoblast culture. However, I couldn't observe the alteration of expression/secretion because FGF23 was not expressed in human osteoblasts we used.
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Report
(3 results)
Research Products
(1 results)
