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Neural correlates of mother擁nfant interaction and effect of neonatal intensive care unit environment on the interaction

Research Project

Project/Area Number 21790995
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Pediatrics
Research InstitutionKyushu University

Principal Investigator

SANEFUJI Masafumi  九州大学, 大学病院, 助教 (50467940)

Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords母子相互作用 / 新生児集中治療室 / 近赤外線分光法 / connectivity analysis / 近赤外線光法
Research Abstract

To elucidate the functional evidence of motherinfant interaction, we made simultaneous monitoring of cerebral activation in infants and their mothers, using nearinfrared spectroscopy(NIRS). We found high correlation between the activation of infants and that of mothers when the mothers held their own infants at rest, suggesting motherinfant interaction. We also monitored cerebral activation in premature infants using NIRS and confirmed that correlation between different brain areas depends on brain maturation and disabilities of the infants.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (49 results)

All 2012 2011 2010 2009 Other

All Journal Article (20 results) (of which Peer Reviewed: 18 results) Presentation (28 results) Remarks (1 results)

  • [Journal Article] Clinical and genetic characterization of a 2-year-old boy with complete PLP1 deletion2012

    • Author(s)
      Torisu, Iwaki, et al
    • Journal Title

      Brain Dev

      Volume: (In press) Issue: 10 Pages: 852-856

    • DOI

      10.1016/j.braindev.2012.02.006

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] trategy in short-term memory for pictures in childhood2011

    • Author(s)
      Sanefuji M, Takada Y, Kimura N et al
    • Journal Title

      a near-infrared spectroscopy study, Neuroimage

      Volume: 54 Pages: 2394-2400

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Clinical and MRI characteristics of acute encephalopathy in congenital adrenal hyperplasia2011

    • Author(s)
      Li S, Sanefuji M, Watanabe K et al
    • Journal Title

      J Neurol Sci

      Volume: 306 Pages: 91-93

    • NAID

      120005133038

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Clinical and MRI characteristics of acute encephalopathy in congenital adrenal hyperplasia2011

    • Author(s)
      Lee S, Sanefuji, M, Watanabe K, Uematsu A, Torisu, H, Baba H, Kira, R, Takada Y, Ishizaki Y, Toyoshima M, Aragaki F, Hata D, Hara T
    • Journal Title

      J Neurol Sci

      Volume: 306 Issue: 1-2 Pages: 91-93

    • DOI

      10.1016/j.jns.2011.03.037

    • NAID

      120005133038

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Parental age and child growth and development2011

    • Author(s)
      Iwayama M, Kira, R, Kinukawa N, Sakai Y, Torisu, H, Sanefuji, M, Ishizaki Y, Nose Y, Matsumoto T, Hara T
    • Journal Title

      child health check蓉p data

      Volume: 53 Issue: 5 Pages: 709-714

    • DOI

      10.1111/j.1442-200x.2011.03331.x

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Strategy in short-term memory for pictures in childhood : Anear-infrared spectroscopy study.2011

    • Author(s)
      Sanefuji, et al.
    • Journal Title

      Neuroimage

      Volume: 54 Pages: 2394-400

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Parental ages and the growth and development of children: a study from check-ups.2011

    • Author(s)
      Iwayama M,…, Sanefuji M, et al.
    • Journal Title

      Pediatr Int

      Volume: (Epub)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Clinical and MRI characteristics of acute encephalopathy in congenital adrenal hyperplasia.2011

    • Author(s)
      Li S, Sanefuji M, et al.
    • Journal Title

      J Neurol Sci

      Volume: (accepted)

    • NAID

      120005133038

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Autopsy case of later-onset pontocerebellar hypoplasia type 1 : pontine atrophy and pyramidal tract involvement2010

    • Author(s)
      Sanefuji M, Kira R, Matsumoto K et al
    • Journal Title

      J Child Neurol

      Volume: 25 Pages: 1429-1434

    • NAID

      120005227141

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] 重症筋無力症・stiff-person症候群ここまでわかっている自己抗体と自己免疫疾患2010

    • Author(s)
      實藤雅文
    • Journal Title

      小児科診療

      Volume: 73巻 Pages: 2144-2148

    • Related Report
      2011 Final Research Report
  • [Journal Article] Autopsy case of later-onset pontocerebellar hypoplasia type 1 : pontine atrophy and pyramidal tract involvement.2010

    • Author(s)
      Sanefuji M, et al.
    • Journal Title

      J Child Neurol

      Volume: 25 Pages: 1429-34

    • NAID

      120005227141

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 重症筋無力症・stiff-person症候群 ここまでわかっている自己抗体と自己免疫疾患2010

    • Author(s)
      實藤雅文
    • Journal Title

      小児科診療

      Volume: 73 Pages: 2144-8

    • Related Report
      2010 Annual Research Report
  • [Journal Article] PD1 as a common candidate susceptibility gene of subacute sclerosing panencephalitis.2010

    • Author(s)
      Ishizaki Y,…, Sanefuji M, et al.
    • Journal Title

      Hum Genet

      Volume: 127 Pages: 411-9

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Clinical study of childhood acute disseminated encephalomyelitis, multiple sclerosis, and acute transverse myelitis in Fukuoka Prefecture, Japan2010

    • Author(s)
      Torisu H,…, Sanefuji M, et al.
    • Journal Title

      Brain Dev

      Volume: 32 Pages: 454-62

    • NAID

      10027491651

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] PD1 as a common candidate susceptibihty gene of subacute sclerosing panencephalitis.2010

    • Author(s)
      Ishizaki Y,---, Sanefuji M, et al.
    • Journal Title

      Hum Genet (Epub)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genetic susceptibihty to febrile seizures : case-control association studies.2010

    • Author(s)
      Kira R ,---, Sanefuji M, et al.
    • Journal Title

      Brain Dev 32

      Pages: 57-63

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Rhombencep-halitis and coxackievirus2009

    • Author(s)
      Goto K, Sanefuji M, Kusuhara K et al
    • Journal Title

      Emerg Infect Dis

      Volume: 15 Pages: 1689-1691

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Rhombencephalitis and coxsackievirus A16.2009

    • Author(s)
      Goto K, Sanefuji M, et al.
    • Journal Title

      Emerg Infbct Dis 15

      Pages: 1689-1691

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Chnical study of childhood acute disseminated encephalolnyehtis, multiple sclerosis, and acute transverse myehtis in Fukuoka Prefecture, Japan2009

    • Author(s)
      Torisu H,---, Sanefuji M, et al.
    • Journal Title

      Brain Dev (Epub)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Interleukin-10 is associated with resistance to febrile seizures : genetic a ssociation and experimental animal studies.2009

    • Author(s)
      Ishizaki Y,---, Sanefuji M, et al.
    • Journal Title

      Epilepsia 50

      Pages: 761-767

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] NIRSにおける、ヘモグロビン濃度変化量の比率を用いた解析法の有用性2011

    • Author(s)
      實藤雅文、高田結、鳥巣浩幸、他
    • Organizer
      第13回日本ヒト脳機能マッピング学会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-01
    • Related Report
      2011 Final Research Report
  • [Presentation] NIRSにおける、ヘモグロビン濃度変化量の比率を用いた解析法の有用性2011

    • Author(s)
      實藤雅文, 他
    • Organizer
      日本ヒト脳機能マッピング学会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] NIRSの特性を生かした研究手法~ヘモグロビン濃度変化量の比率を用いた解析法~2011

    • Author(s)
      實藤雅文
    • Organizer
      第14回日本光脳機能イメージング研究会
    • Place of Presentation
      東京
    • Year and Date
      2011-07-23
    • Related Report
      2011 Final Research Report
  • [Presentation] NIRSの特性を生かした研究手法~ヘモグロビン濃度変化量の比率を用いた解析法~2011

    • Author(s)
      實藤雅文
    • Organizer
      第14回日本光脳機能イメージング研究会
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2011-07-23
    • Related Report
      2011 Annual Research Report
  • [Presentation] 急性脳炎・脳症を疑われた乳児ボツリヌス症の1例2011

    • Author(s)
      實藤雅文、李守永、鳥巣浩幸、他
    • Organizer
      第53回日本小児神経学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2011-05-26
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] Strategy in short-term memory for pictures in childhood : an event-relatednear-infrared spectroscopy study2011

    • Author(s)
      SanefujiM, TakadaY, Kimura N et al
    • Organizer
      The 7th congress ofasian society for pediatric research
    • Place of Presentation
      Denver
    • Year and Date
      2011-05-02
    • Related Report
      2011 Final Research Report
  • [Presentation] Strategy in short-term memory for pictures in childhood : an event-related near-infrared spectroscopy study2011

    • Author(s)
      Sanefuji M, et al
    • Organizer
      The 7th Congress of Asian Society for Pediatric Research
    • Place of Presentation
      Denver, USA
    • Year and Date
      2011-05-02
    • Related Report
      2011 Annual Research Report
  • [Presentation] 当初、急性脳症・脳幹脳炎と診断された乳児ボツリヌス症の1例2011

    • Author(s)
      長友雄作、實藤雅文, 他
    • Organizer
      第70回日本小児神経学会九州地方会
    • Place of Presentation
      佐賀
    • Year and Date
      2011-01-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] SPECTにて大脳半球血流低下を呈した転換性障害の一例2010

    • Author(s)
      小林真直、實藤雅文, 他
    • Organizer
      第462回日本小児科学会福岡地方会
    • Place of Presentation
      福岡
    • Year and Date
      2010-12-11
    • Related Report
      2010 Annual Research Report
  • [Presentation] シンポジウムI :子どもの食欲と心身の発育小児の食行動の異常と「こころの問題」2010

    • Author(s)
      實藤雅文
    • Organizer
      第28回日本小児歯科学会九州地方会大会
    • Place of Presentation
      福岡
    • Year and Date
      2010-10-03
    • Related Report
      2011 Final Research Report
  • [Presentation] シンポジウムI:子どもの食欲と心身の発育 小児の食行動の異常と「こころの問題」2010

    • Author(s)
      實藤雅文
    • Organizer
      第28回日本小児歯科学会九州地方会大会
    • Place of Presentation
      福岡
    • Year and Date
      2010-10-03
    • Related Report
      2010 Annual Research Report
  • [Presentation] 脱力発作を示すてんかん~臨床像と脳波~2010

    • Author(s)
      實藤雅文
    • Organizer
      第192回てんかん懇話会
    • Place of Presentation
      福岡
    • Year and Date
      2010-07-22
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] カフアシストを用い人工呼吸器管理を回避できた非古典型乳児型Pompe病の一例2010

    • Author(s)
      村田憲治、實藤雅文, 他
    • Organizer
      第5回日本ポンペ病研究会
    • Place of Presentation
      東京
    • Year and Date
      2010-06-13
    • Related Report
      2010 Annual Research Report
  • [Presentation] 急性脳症の宿主側要因:急性脳症を発症した先天性副腎皮質過形成患者の臨床像、MRI所見の検討2010

    • Author(s)
      李守永、實藤雅文, 他
    • Organizer
      第52回日本小児神経学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2010-05-23
    • Related Report
      2010 Annual Research Report
  • [Presentation] 短期記憶における音韻戦略の発達:近赤外線分光法による研究2010

    • Author(s)
      實藤雅文、山口結、木村直子、他
    • Organizer
      第52回日本小児神経学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2010-05-22
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 小児期に診断したファブリー病の臨床像について-自験例4例の検討-2010

    • Author(s)
      礒部菜摘、實藤雅文, 他
    • Organizer
      第52回日本小児神経学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2010-05-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] 肝腫大・心拡大を呈したフロッピーインファントの1例2010

    • Author(s)
      伊藤雄哉、實藤雅文, その他
    • Organizer
      第68回日本小児神経学会九州地方会
    • Place of Presentation
      宮崎
    • Year and Date
      2010-01-10
    • Related Report
      2009 Annual Research Report
  • [Presentation] 他食行動異常をきたした子どものこころと家族の問題2009

    • Author(s)
      實藤雅文、吉良龍太郎、鳥巣浩幸
    • Organizer
      福岡学校精神保健協議会
    • Place of Presentation
      福岡
    • Year and Date
      2009-11-24
    • Related Report
      2011 Final Research Report
  • [Presentation] 食行動異常をきたした子どものこころと家族の問題2009

    • Author(s)
      實藤雅文、吉良龍太郎, その他
    • Organizer
      福岡学校精神保健協議会
    • Place of Presentation
      福岡
    • Year and Date
      2009-11-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] インフルエンザ脳症を合併したCAH(先天性副腎皮質過形成)の一例2009

    • Author(s)
      小野宏彰、實藤雅文, その他
    • Organizer
      第456回日本小児科学会福岡地方会例会
    • Place of Presentation
      福岡
    • Year and Date
      2009-10-10
    • Related Report
      2009 Annual Research Report
  • [Presentation] 他食行動の異常を主訴に「子どものこころと発達外来」を受診した学童3例の検討2009

    • Author(s)
      實藤雅文、山下洋、出口美奈子
    • Organizer
      第57回九州学校保健学会
    • Place of Presentation
      福岡
    • Year and Date
      2009-08-23
    • Related Report
      2011 Final Research Report
  • [Presentation] 食行動の異常を主訴に「子どものこころと発達外来」を受診した学童3例の検討2009

    • Author(s)
      實藤雅文、山下洋, その他
    • Organizer
      第57回九州学校保健学会
    • Place of Presentation
      福岡
    • Year and Date
      2009-08-23
    • Related Report
      2009 Annual Research Report
  • [Presentation] 発熱、意識障害を呈した先天性副腎皮質過形成の9歳女児例2009

    • Author(s)
      李守永、實藤雅文, その他
    • Organizer
      第67回日本小児神経学会九州地方会
    • Place of Presentation
      久留米
    • Year and Date
      2009-08-02
    • Related Report
      2009 Annual Research Report
  • [Presentation] 他小児期のリハーサル過程の発達:事象関連近赤外線分光法による研究2009

    • Author(s)
      實藤雅文、山口結、木村直子
    • Organizer
      第11回日本光脳機能イメージング研究会
    • Place of Presentation
      東京
    • Year and Date
      2009-07-18
    • Related Report
      2011 Final Research Report
  • [Presentation] 小児期のリハーサル過程の発達:事象関連近赤外線分光法による研究2009

    • Author(s)
      實藤雅文、山口結, その他
    • Organizer
      第11回光脳機能イメージング研究会
    • Place of Presentation
      東京
    • Year and Date
      2009-07-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] 他食行動の異常を主訴に受診した症例の検討2009

    • Author(s)
      實藤雅文、吉良龍太郎、鳥巣浩幸
    • Organizer
      第51回日本小児神経学会総会
    • Place of Presentation
      米子
    • Year and Date
      2009-05-28
    • Related Report
      2011 Final Research Report
  • [Presentation] 「食行動の異常」を主訴に受診した症例の検討2009

    • Author(s)
      實藤雅文、吉良龍太郎, その他
    • Organizer
      第51回日本小児神経学会総会
    • Place of Presentation
      米子
    • Year and Date
      2009-05-28
    • Related Report
      2009 Annual Research Report
  • [Presentation] 痙性対麻痺で発症したアルギナーゼ欠損症の10歳男児例2009

    • Author(s)
      杉谷雄一郎、實藤雅文, その他
    • Organizer
      第112回日本小児科学会学術集会
    • Place of Presentation
      奈良
    • Year and Date
      2009-04-19
    • Related Report
      2009 Annual Research Report
  • [Remarks]

    • URL

      http://www.med.kyushu-u.ac.jp/pediatr/index.html

    • Related Report
      2011 Final Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

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