Possible role of cAMP guanine nucleotide exchange factor (Epac) in human placentation
| Project/Area Number |
21791044
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Embryonic/Neonatal medicine
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| Research Institution | Tokyo University of Pharmacy and Life Science |
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Principal Investigator |
YOSHIE Mikihiro Tokyo University of Pharmacy and Life Science, 薬学部, 助教 (50434014)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | Epac / 栄養膜細胞 / 脱落膜細胞 / 胎盤 / シンシチウム化 / 絨毛性ゴナドトロピン / プロゲステロン |
|---|
| Research Abstract |
In this study, we demonstrated that cAMP-mediated Epac/Rap1 signaling pathway may regulate trophoblast cell differentiation and syncytialization and endometrial stromal cell decidualization which are crucial for human placentation.
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Report
(3 results)
Research Products
(16 results)
