Investigation of the role of IL-17-producing-cells in tumor immunity and tumor vaccine immunity.
| Project/Area Number |
21791077
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Dermatology
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| Research Institution | Kobe University |
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Principal Investigator |
ONIKI Shuntar Kobe University, 大学院・医学研究科, 医学研究員 (50448180)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | IL-17 / 腫瘍免疫 / 腫瘍ワクチン / IL-17産生細胞 / 抗腫瘍免疫 |
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| Research Abstract |
In our experimental model, IL-17 had no effect on tumor immunity or tumor vaccine immunity of B16F10 mouse melanoma. But, only in IL-12, not in IL-23 or IL-27, derived tumor immunity to B16F10 mouse melanoma, OX40, one of TNFR family members, had an important role associated with IL-17.
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Report
(3 results)
Research Products
(5 results)
