The role of PTEN in melanocyte stem cell maintainance in aged hair graying model mice
| Project/Area Number |
21791091
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Dermatology
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| Research Institution | Jichi Medical University |
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Principal Investigator |
NARITA Tae Jichi Medical University, 医学部, 助教 (10301061)
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| Project Period (FY) |
2009 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 色素細胞学 / 幹細胞 |
|---|
| Research Abstract |
To clarify the role of PTEN in melanocyte stem cell maintainance in hair graying, we studied PTEN role in bcl-2 null, or mitf mutant mice, which are known as hair graying model mice. We generated PTEN and bcl-2, or PTEN and mitf double mutant mice, and now studying their hair color change in natural aging.
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Report
(3 results)
Research Products
(13 results)
