Comprehensive genetic analysis of CABIN1 in schizophrenia
| Project/Area Number |
21791114
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Psychiatric science
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| Research Institution | Niigata University |
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Principal Investigator |
WATANABE Yuichiro Niigata University, 保健管理センター, 講師 (90401744)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2009: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | 統合失調症 / 関連解析 / コピー数多様性 |
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| Research Abstract |
The gene encoding calcineurin binding protein 1 (CABIN1) is a promising candidate gene for schizophrenia. To assess whether CABIN1 is implicated in vulnerability to schizophrenia, we conducted a case-control association study between CABIN1 and schizophrenia. The results revealed no evidence of an association between CABIN1 and schizophrenia using 11 tagging single nucleotide polymorphisms and a copy number variation. Our results suggest that CABIN1 may not confer increased susceptibility for schizophrenia.
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Report
(3 results)
Research Products
(57 results)
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[Journal Article] Failure to find an association between myosin heavy chain 9, non-muscle (MYH9) and schizophrenia : a three-stage case-control association study.2010
Author(s)
Amagane, H., Watanabe, Y., Kaneko, N., Nunokawa, A., Muratake, T., Ishiguro, H., Arinami, T., Ujike, H., Inada, T., Iwata, N., Kunugi, H., Sasaki, T., Hashimoto, R., Itokawa, M., Ozaki, N., Someya, T.
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Journal Title
Schizophrenia Research 118
Pages: 106-112
Related Report
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[Journal Article] The dopamine D3 receptor (DRD3) gene and risk of schizophrenia : case-control studies and an updated meta-analysis.2010
Author(s)
Nunokawa, A., Watanabe, Y., Kaneko, N., Sugai, T., Yazaki, S., Arinami, T., Ujike, H., Inada, T., Iwata, N., Kunugi, H., Sasaki, T., Itokawa, M., Ozaki, N., Hashimoto, R., Someya, T.
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Journal Title
Schizophrenia Research 116
Pages: 61-67
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[Journal Article] A two-stage case-control association study of PADI2 with schizophrenia.2009
Author(s)
Watanabe, Y., Nunokawa, A., Kaneko, K., Arinami, T., Ujike, H., Inada, T., Iwata, N., Kunugi, H., Itokawa, M., Otowa, T., Ozaki, N., Someya, T.
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Journal Title
Journal of Human Genetics 54
Pages: 430-432
NAID
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[Presentation] ミオシン重鎖9遺伝子は統合失調症と関連しない2010
Author(s)
渡部雄一郎, 天金秀樹, 金子尚史, 布川綾子, 村竹辰之, 石黒浩毅, 有波忠雄, 氏家寛, 稲田俊也, 岩田仲生, 功刀浩, 佐々木司, 橋本亮太, 糸川昌成, 尾崎紀夫, 染矢俊幸
Organizer
第32回日本生物学的精神医学会
Place of Presentation
リーガロイヤルホテル小倉(北九州市)
Year and Date
2010-10-09
Related Report
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[Presentation] ドパミンD3受容体遺伝子と統合失調症のリスク2010
Author(s)
布川綾子, 渡部雄一郎, 金子尚史, 須貝拓朗, 矢崎沙織, 有波忠雄, 氏家寛, 稲田俊也, 岩田仲生, 功刀浩, 佐々木司, 糸川昌成, 尾崎紀夫, 橋本亮太, 染矢俊幸
Organizer
第32回日本生物学的精神医学会
Place of Presentation
リーガロイヤルホテル小倉(北九州市)
Year and Date
2010-10-09
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[Presentation] 二段階サンプルによる関節リウマチ感受性遺伝子と統合失調症との関連研究2009
Author(s)
金子尚史, 渡部雄一郎, 布川綾子, 村竹辰之, 有波忠雄, 氏家寛, 稲田俊也, 岩田仲生, 功刀浩, 糸川昌成, 音羽健司, 尾崎紀夫, 染矢俊幸
Organizer
第31回日本生物学的精神医学会.
Place of Presentation
国立京都国際会館(京都市)
Year and Date
2009-04-25
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