A research of aberrant brain volume and function and biological marker in patients with autism spectrum disorders.
| Project/Area Number |
21791120
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Psychiatric science
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| Research Institution | University of Fukui |
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Principal Investigator |
KOSAKA Hirotaka 福井大学, 子どものこころの発達研究センター, 特命准教授 (70401966)
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| Project Period (FY) |
2009 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | 児童・思春期精神医学 / 自閉症スペクトラム障害 / voxel based morphometry (VBM) / functional MRI (fMRI) / オキシトシン / 社会性の障害 / 右島 / 右下前頭回 / 児童思春期精神医学 / 広汎性発達障害(PDD) / 共同注視 / アイコンタクト / コミュニケーション / 自己顔認知 / 右下前頭葉 / 右側島 / 広汎性発達障害(Pervasive Developmental Disorders ; PDD) / 自閉症(自閉性障害) / アスペルガー障害 / Voxel Based Morphometry (VBM) / Diffusion tensor imaging (DTI) / 血液検査 |
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| Research Abstract |
Much evidence indicates that patients with autism spectrum disorders (ASD) demonstrate marked social dysfunction. However,the etiology is still unknown. We have studied social dysfunctions in youth with high-functioning ASD compared with typically developing participants using voxel-based morphometry and functional MRI. These aberrant neuroimaging findings could be social brain marker in ASD. Next, I reported oxytocin effect to a patient with ASD
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Report
(5 results)
Research Products
(61 results)
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[Journal Article] Emotional responses associated with self-face processing in individuals with autism spectrum disorders : An fMRI study2012
Author(s)
Morita, T., Kosaka, H., Saito, D., Ishitobi, M., Munesue, T., Itakura, S., et al
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Journal Title
Social Neuroscience
Volume: 7(3)
Issue: 3
Pages: 223-239
DOI
Related Report
Peer Reviewed
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[Journal Article] Hard to "tune in" : neural mechanisms of live face-to-face interaction with high-functioning autistic spectrum disorder2012
Author(s)
Tanabe HC, Kosaka H, Saito DN, Koike T, Hayashi MJ, Izuma K, Komeda H, Ishitobi M, Omori M, Munesue T, Okazawa H, Wada Y, Sadato N
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Journal Title
Front Hum Neurosci
Volume: 6
Pages: 268-268
DOI
Related Report
Peer Reviewed
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