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the relation between cerebral blood flow and function of cognition and memory in unilateral ECT for major depression

Research Project

Project/Area Number 21791122
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Psychiatric science
Research InstitutionUniversity of Yamanashi

Principal Investigator

YASUDA Kazuyuki  University of Yamanashi, 医学部附属病院, 助教 (90456442)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords電気けいれん療法 / ECT / 脳血流 / うつ病 / 認知機能 / SPECT / 電極配置
Research Abstract

Twelve depressive patients who had agreed with this study received unilateral electroconvulsive therapy (ECT). We found the lower seizure thresholds at first session and the equivalent clinical rating scores that the depressive symptoms improved and the cognitive functions did not change. The less total cerebral blood flows were measured at three months after ECT than before and one week after ECT on single photon emission computed tomography (SPECT). The regional cerebral blood flows did not change significantly. We could not clarify the relation between clinical symptoms and cerebral blood flows.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (5 results)

All 2010 2009

All Presentation (5 results)

  • [Presentation] うつ病に対する高用量片側性電気けいれん療法の有用性について2010

    • Author(s)
      北原裕一, ほか
    • Organizer
      第106回日本精神神経学会学術総会
    • Place of Presentation
      広島国際会議場・アステールプラザ
    • Year and Date
      2010-05-22
    • Related Report
      2010 Final Research Report
  • [Presentation] 高用量片側性電気けいれん療法の有用性について2010

    • Author(s)
      北原裕一, ほか
    • Organizer
      第106回日本精神神経学会学術総会
    • Place of Presentation
      広島
    • Year and Date
      2010-05-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] 高用量右片側性電気けいれん療法と脳機能画像変化の関連について2009

    • Author(s)
      安田和幸, ほか
    • Organizer
      第42回精神神経系薬物治療研究報告会
    • Place of Presentation
      大阪千里ライフサイエンスセンター
    • Year and Date
      2009-12-04
    • Related Report
      2010 Final Research Report
  • [Presentation] 治療抵抗性うつ病に対する治療システム構築のための研究-電気けいれん療法を中心に-2009

    • Author(s)
      安田和幸, ほか
    • Organizer
      厚生労働省精神・神経疾患研究委託費研究報告会
    • Place of Presentation
      アルカディア市ヶ谷
    • Year and Date
      2009-11-30
    • Related Report
      2010 Final Research Report
  • [Presentation] 電気けいれん療法の進歩2009

    • Author(s)
      安田和幸, ほか
    • Organizer
      第19回日本臨床精神神経薬理学会・第39回日本神経精神薬理学会合同年会
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2009-11-14
    • Related Report
      2010 Final Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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