Investigation of changes in autonomic brain activity by aging and mild cognitive impairment

• Project/Area Number: 21791162
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Psychiatric science
• Research Institution: National Center for Geriatrics and Gerontology
• Principal Investigator: MIYAKOSHI Makoto 独立行政法人国立長寿医療研究センター, 長寿医療工学研究部, 外来研究員 (00508046)
• Project Period (FY): 2007 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000); Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
• Keywords: 老化 / 神経科学 / EEG-fMRI同時計測 / 信号解析 / 痴呆

Research Abstract

I established the methodology in the use of both hardware and software to investigate brain activity of older adults while minimizing load. To identify age-related difference, I compare healthy young subjects with healthy older subjects. Comparison results revealed that the special extent of the resting state cortical network in older adults was limited compared to that of younger subjects.

Research Products

• [Journal Article] Extensive stimulus repetition leads older adults to show delayed functional magnetic resonance imaging adaptation (2012)
  • Author(s): Miyakoshi M, Chen AS, Matsuo K, Wu CY, Suzuki A, Nakai T
  • Journal Title: Brain Imaging and Behavior Volume: (accepted) Issue: 3 Pages: 357-365
  • DOI: 10.1007/s11682-012-9148-5
  • Peer Reviewed
• [Journal Article] White matter connectivity between superior temporal sulcus and amygdala is associated with autistic trait in healthy humans (2012)
  • Author(s): Iidaka T, Miyakoshi M, Harada T, Nakai T
  • Journal Title: Neuroscience Letters Volume: 510 Issue: 2 Pages: 154-158
  • DOI: 10.1016/j.neulet.2012.01.029
  • Peer Reviewed
• [Journal Article] 認知症予防のための指運動訓練の定量的画像計測技術の開発 (2010)
  • Author(s): 宮腰誠, 他
  • Journal Title: 研究医科学研究助成論文集 25 Pages: 102-113
  • Peer Reviewed
• [Presentation] Multivariate vector analysis on EEG during visual self-recognition (2011)
  • Author(s): Miyakoshi, M., Mullen, T., Makeig, S.
  • Organizer: Talk at Tohoku University (Sendai, November) Nov 2011
  • Place of Presentation: 東北大学
  • Year and Date: 2011-11-21
• [Presentation] 「私」のスピード、その計算神経科学的根拠 (2011)
  • Author(s): 宮腰誠, Tim Mullen, Scott Makeig
  • Organizer: 日本人間行動進化学会第4回大会
  • Place of Presentation: 北海道大学
  • Year and Date: 2011-11-19
• [Presentation] シールドからフィールドへ-脳波計測と解析の実際- (2011)
  • Author(s): 宮腰誠、松本敦、金山範明、小野田慶一
  • Organizer: 日本心理学会第75回大会ワークショップWS117
  • Place of Presentation: 東洋大学
  • Year and Date: 2011-09-17
• [Presentation] Comparison of two approaches to the resting state : spatial ICA and EEG alpha-band correlates (2011)
  • Author(s): Miyakoshi, M., Miyauchi, S., Koike, T., Kan, S., Nakai, T.
  • Organizer: 17th Annual meeting of Human Brain Mapping
  • Place of Presentation: カナダ国ケベック
  • Year and Date: 2011-06-28
• [Presentation] What is ICA and Why ICA/Salvaging EEG from MEI artifact using ICA (2011)
  • Author(s): Miyakoshi, M., Nakai, T., Makeig, S.
  • Organizer: EEG workshop as McGill University
  • Place of Presentation: カナダ国モントリオール
  • Year and Date: 2011-05-11
• [Presentation] Aging effect on the resting state : two complementary approaches with the same fMRI datasets (2011)
  • Author(s): Miyakoshi, M., Miyauchi, S., Koike, T., Kan, S., Nakai, T.
  • Organizer: 19th Annual meeting of international society for magnetic resonance in medicine
  • Place of Presentation: カナダ国モントリオール
  • Year and Date: 2011-05-09
• [Presentation] Comparison of two approaches to the resting state : spatial ICA and EEG alpha-band correlates (2011)
  • Author(s): Miyakoshi, M., Miyauchi, S., Koike, T., Kan, S., Nakai, T
  • Organizer: 17th Annual meeting of Human Brain Mapping
  • Place of Presentation: Quebec
• [Presentation] Aging effect on the resting state : two complementary approaches with the same fMRI datasets (2011)
  • Author(s): Miyakoshi, M., Miyauchi, S., Koike, T., Kan, S., Nakai, T
  • Organizer: 19th Annual meeting of international society for magnetic resonance in medicine
  • Place of Presentation: Montreal
• [Presentation] 島は私を呼ぶ声を聞くか (2010)
  • Author(s): 宮腰誠, 他
  • Organizer: 第3回人間行動進化学会73回全国大会
  • Place of Presentation: 神戸大学
  • Year and Date: 2010-12-04
• [Presentation] アルファ波相関皮質領域とデフォルトモードネットワークの比較 (2010)
  • Author(s): 宮腰誠, 他
  • Organizer: 平成22年度日本生体医工学東海支部大会
  • Place of Presentation: スズケン本社(愛知県)
  • Year and Date: 2010-10-16
• [Presentation] 注意時・非注意時における名前が呼ばれた時の脳活動の検討 (2010)
  • Author(s): 中根俊樹, 他
  • Organizer: 平成22年度日本生体医工学東海支部大会
  • Place of Presentation: スズケン本社(愛知県)
  • Year and Date: 2010-10-16
• [Presentation] 色トラッキングを用いた脳機能計測中の運動計測の試み (2010)
  • Author(s): 畑中渉, 他
  • Organizer: 平成22年度日本生体医工学東海支部大会
  • Place of Presentation: スズケン本社(愛知県)
  • Year and Date: 2010-10-16
• [Presentation] 血液動態反応に見られる加齢性変化の機序 (2010)
  • Author(s): 中井敏晴, 他
  • Organizer: 平成22年度日本生体医工学東海支部大会
  • Place of Presentation: スズケン本社(愛知県)
  • Year and Date: 2010-10-16
• [Presentation] 視覚的自己認知の脳波研究(指定討論者) (2010)
  • Author(s): 宮腰誠
  • Organizer: 第28回日本生理心理学会 シンポジウム「顔識別の生理心理学的研究から社会性認知を探る」
  • Place of Presentation: 茨城大学教育学部D棟201
  • Year and Date: 2010-05-15
• [Presentation] 「私」は位相ががそろってない、とはどういうことか (2010)
  • Author(s): 宮腰誠, 他
  • Organizer: 第4回YERP研究会
  • Place of Presentation: ホリデイ,イン水戸
  • Year and Date: 2010-05-14
• [Presentation] The dependency of age-related change of brain activation on the visual stimuli-Demand-reservation balance (2010)
  • Author(s): Nakai T, et al.
  • Organizer: ISMRM-ESMRMB Joint Annual Meeting 2010
  • Place of Presentation: Stockholm International Fairs, Stockholm, Sweden
  • Year and Date: 2010-05-05
• [Presentation] The hemodynamic response characteristics underlying the age-related change of brain activation during motor execution (2010)
  • Author(s): Nakai T, et al.
  • Organizer: ISMRM-ESMRMB Joint Annual Meeting 2010
  • Place of Presentation: Stockholm International Fairs, Stockholm, Sweden
  • Year and Date: 2010-05-05
• [Presentation] Compromised temporal responsivity in fusiform areas by aging (2010)
  • Author(s): Miyakoshi M, et al.
  • Organizer: ISMRM-ESMRMB Joint Annual Meeting 2010
  • Place of Presentation: Stockholm International Fairs, Stockholm, Sweden
  • Year and Date: 2010-05-04
• [Presentation] アルファ波相関皮質領域とデフォルトネットワークの比較 (2010)
  • Author(s): 宮腰誠・宮内哲・寒重之・小池耕彦・中井敏晴
  • Organizer: 平成22年度日本生体医工学会東海学術集会
  • Place of Presentation: 名古屋
• [Presentation] デフォルトモードネットワークとアルファ波相関領域の比較 (2010)
  • Author(s): 宮腰誠・宮内哲・小池耕彦・寒重之・中井敏晴
  • Organizer: 第38回日本磁気共鳴医学会大会
  • Place of Presentation: つくば
• [Presentation] Hearing one's own name activates the medial frontal area? (2010)
  • Author(s): Nakane T
  • Organizer: 16th Annual Meeting of the Organization for Human Brain Mapping
  • Place of Presentation: Palacio de Congressos de Catalunya, Barcelona, Spain
• [Presentation] HRF Analysis of Age-related Decline of Brain Activation (2010)
  • Author(s): Nakai T, et al.
  • Organizer: 16th Annual Meeting of the Organization for Human Brain Mapping
  • Place of Presentation: Palacio de Congressos de Catalunya, Barcelona, Spain
• [Presentation] Compromised temporal responsivity in fusiform areas by aging (2010)
  • Author(s): Miyakoshi M, et al.
  • Organizer: 16th Annual Meeting of the Organization for Human Brain Mapping
  • Place of Presentation: Palacio de Congressos de Catalunya, Barcelona, Spain
• [Presentation] Age-related Changes in Semantic Processing (2010)
  • Author(s): Miyakoshi M, et al.
  • Organizer: 16th Annual Meeting of the Organization for Human Brain Mapping
  • Place of Presentation: Palacio de Congressos de Catalunya, Barcelona, Spain
• [Presentation] BOLD信号の加齢性変化を反映する神経負荷モデルの研究 (2010)
  • Author(s): 中井敏晴, 他
  • Organizer: 第38回日本磁気共鳴医学会大会
  • Place of Presentation: つくば国際会議場
• [Presentation] 画像計測による行動データを指標としたfMRIデータ評価の試み (2010)
  • Author(s): 畑中渉, 他
  • Organizer: 第38回日本磁気共鳴医学会大会
  • Place of Presentation: つくば国際会議場
• [Presentation] 名前に対する注意は前頭葉内側の脳活動に反映される (2010)
  • Author(s): 中根俊樹, 他
  • Organizer: 第38回日本磁気共鳴医学会大会
  • Place of Presentation: つくば国際会議場
• [Presentation] 加齢が単語の意味処理に与える影響のfMRI研究 (2010)
  • Author(s): 宮腰誠, 他
  • Organizer: 第38回日本磁気共鳴医学会大会
  • Place of Presentation: つくば国際会議場
• [Presentation] デフォルトモードネットワークとアルファ波相関領域の比較 (2010)
  • Author(s): 宮腰誠, 他
  • Organizer: 第38回日本磁気共鳴医学会大会
  • Place of Presentation: つくば国際会議場
• [Presentation] 認知症の早期診断のための安静時脳活動のEEG-fMRI同時計測 (2009)
  • Author(s): 宮腰誠, 中井敏晴
  • Organizer: 日本生体医工学会東海支部学術集会
  • Place of Presentation: 株式会社スズケン本社2階会議室
  • Year and Date: 2009-10-17
• [Remarks]
  • URL: http://researchmap.jp/read0147913
• [Remarks]
  • URL: http://researchmap.jp/read0147913/?lang=english
• [Remarks]
  • URL: http://jglobal.jst.go.jp/public/20090422/200901074573046066