• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Clinical application of diffusion tensor imaging for the skeletal muscle

Research Project

Project/Area Number 21791169
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Radiation science
Research InstitutionUniversity of Tsukuba

Principal Investigator

OKAMOTO Yoshikazu  筑波大学, 医学医療系, 講師 (90420083)

Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywordsコンディショニング / トラクトグラフィー / 拡散テンソル / 核磁気共鳴スペクトロスコピー / 細胞内脂肪 / 骨格筋 / MRスペクトロスコピー / 拡散強調画画像 / IVIM / 生活習慣病 / 筋損傷 / 筋代謝 / 筋血流
Research Abstract

It is very rare to perform skeletal muscle MRI in the daily practice. However, we applied diffusion tensor imaging (DTI), which was new imaging technique, to the skeletal muscle, and we could make it possible to depict skeletal muscle fiber. In addition, we could grasp the microanatomy of the skeletal muscle by DTI.
Moreover, we could also realize to measure the lipid metabolism at the skeletal muscle using MR spectroscopy.
We have presented these several research results in the conference held in Japan, or the other international meetings. And also we presented it by three research papers during research period.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (31 results)

All 2011 2010 2009

All Journal Article (6 results) (of which Peer Reviewed: 3 results) Presentation (25 results)

  • [Journal Article] Diffusion property differences of the lower leg musculature between athletes and non-athletes using 1.5T MRI2011

    • Author(s)
      Okamoto Y, Mori S, Kujiraoka Y, Nasu K, Hirano Y, Minami M
    • Journal Title

      MAGMA

    • Related Report
      2011 Final Research Report
  • [Journal Article] Diffusion property differences of the lower leg musculature between athletes and non-athletes using 1.5 T MRI2011

    • Author(s)
      Yoshikazu Okamoto, et al.
    • Journal Title

      magnetic resonance materials in physics biology and medicine

      Volume: (Epub ahead of print)(Epub) Issue: 4 Pages: 277-284

    • DOI

      10.1007/s10334-011-0294-3

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Changes in MR diffusion properties during active muscle contraction in the calf2010

    • Author(s)
      Okamoto Y, Kunimatsu A, Kono T, NasuK, Sonobe J, Minami M
    • Journal Title

      Magn Reson Med Sci

      Volume: 9 Pages: 1-8

    • NAID

      10026930210

    • Related Report
      2011 Final Research Report
  • [Journal Article] Gender differences in MR muscle tractography2010

    • Author(s)
      Okamoto Y, Kunimatsu A, Kono T, Kujiraoka Y, Sonobe J, Minami M
    • Journal Title

      Magn Reson Med Sci

      Volume: 9 Pages: 111-118

    • NAID

      10027851249

    • Related Report
      2011 Final Research Report
  • [Journal Article] Gender differences in MR muscle tractography.2010

    • Author(s)
      Okamoto Yoshikazu
    • Journal Title

      Magnetic Resonance in Medical Sciences

      Volume: 9 Pages: 111-118

    • NAID

      10027851249

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Changes in MR diffusion properties during active muscle contraction in the calf2010

    • Author(s)
      Okamoto Yoshikazu
    • Journal Title

      Magnetic Resonance in Medical Sciences 9巻

      Pages: 1-8

    • NAID

      10026930210

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] スロートレーニングが局所の骨格筋脂肪代謝に与える影響の検討2011

    • Author(s)
      岡本嘉一
    • Organizer
      第22回日本臨床スポーツ医学会学術集会
    • Place of Presentation
      青森
    • Year and Date
      2011-11-05
    • Related Report
      2011 Final Research Report
  • [Presentation] 3T 1H-MR spectroscopy(1H-MRS)とLCModelによる骨格筋IMCLとEMCL計測成功率の計測対象による差異の検討2011

    • Author(s)
      岡本嘉一, 磯辺智範, 鈴木浩明, 平野雄二, 南学
    • Organizer
      第39回日本磁気共鳴医学会
    • Place of Presentation
      北九州
    • Year and Date
      2011-09-29
    • Related Report
      2011 Final Research Report
  • [Presentation] Multi-b diffusionを用いた骨格筋細胞内腔と外腔の比率(fraction)測定の試み2011

    • Author(s)
      岡本嘉一, 小原真, 那須克宏, 磯辺智範, 平野雄二, 南学
    • Organizer
      第39回日本磁気共鳴医学会
    • Place of Presentation
      北九州
    • Year and Date
      2011-09-29
    • Related Report
      2011 Final Research Report
  • [Presentation] Elucidation for improvement of visualization in the skeletal muscle tractography using probabilistic diffusion tractography-Preliminary result-ISMRM2011

    • Author(s)
      Okamoto Y, Tadano K, Masumoto T, Hirano Y, Isobe T, Minami M
    • Organizer
      19th Annual Meeting & Exhibition
    • Place of Presentation
      Montreal, Canada
    • Year and Date
      2011-05-08
    • Related Report
      2011 Final Research Report
  • [Presentation] 3T MRIを用いた健常ボランティアの骨格筋細胞内脂肪(IMCL)と身体データの相関性の観察と検討2011

    • Author(s)
      岡本嘉一, 磯辺智範, 平野雄二, 只野喜一, 鈴木浩明, 南学
    • Organizer
      第70会日本医学放射線学会総会
    • Place of Presentation
      震災によりWeb開催
    • Related Report
      2011 Final Research Report
  • [Presentation] 3T MRIを用いた健常ボランティアの骨格筋細胞内脂肪(IMCL)と身体データの相関性の観察と検討2011

    • Author(s)
      岡本嘉一, ほか
    • Organizer
      第70回日本医学放射線学会総会
    • Place of Presentation
      (震災のためWeb発表のみ)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Elucidation for improvement of visualization in the skeletal muscle tractography using probabilistic diffusion tractography-Preliminary result-2011

    • Author(s)
      Yoshikazu Okamoto, et al.
    • Organizer
      International Society for Magnetic Resonance in Medicine 19^<th> annual meeting
    • Place of Presentation
      Montreal, Quebec, Canada
    • Related Report
      2011 Annual Research Report
  • [Presentation] 3T 1H-MR spectroscopy (1H-MRS)とLCModelによる骨格筋IMCLとEMCL計測成功率の計測対象による差異の検討2011

    • Author(s)
      岡本嘉一, ほか
    • Organizer
      第39回日本磁気共鳴医学会大会
    • Place of Presentation
      北九州
    • Related Report
      2011 Annual Research Report
  • [Presentation] Multi-b diffusionを用いた骨格筋細胞内腔と外腔の比率(fraction)測定の試み2011

    • Author(s)
      岡本嘉一, ほか
    • Organizer
      第39回日本磁気共鳴医学会大会
    • Place of Presentation
      北九州
    • Related Report
      2011 Annual Research Report
  • [Presentation] Evaluation of the Change of Intramyocellular Lipid Metabolism due to Long-term Skeletal Muscle Training of the Calf by 3 T H-MR Spectroscopy2010

    • Author(s)
      Yoshikazu Okamoto
    • Organizer
      Radiological society of North America, 96^<th> Scientific Assembly and Annual Meeting
    • Place of Presentation
      Chicago(USA)
    • Year and Date
      2010-11-29
    • Related Report
      2010 Annual Research Report
  • [Presentation] MRI拡散テンソルおよびMR spectroscopy同時撮影による運動効果判定、運動療法効果判定への応用の試み2010

    • Author(s)
      岡本嘉一, 森慎太郎
    • Organizer
      第21回日本臨床スポーツ医学会
    • Place of Presentation
      つくば
    • Year and Date
      2010-11-06
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] Minami M. Evaluation of the Change of Intramyocellular Lipid Metabolism due to Long-term Skeletal Muscle Training of the Calf by 3 T H-MR Spectroscopy. Radiological society of North America2010

    • Author(s)
      Okamoto Y, Isobe T, Hirano Y, Mori S, Tadano K
    • Organizer
      96th Scientific Assembly and Annual Meeting.
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2010-11-01
    • Related Report
      2011 Final Research Report
  • [Presentation] PDTを用いた骨格筋fiber tractography描出の試み~初期経験~2010

    • Author(s)
      岡本嘉一, 只野喜一, 増本智彦, 磯辺智範, 平野雄二, 佐藤英介, 南学
    • Organizer
      第38回日本磁気共鳴医学会大会
    • Place of Presentation
      つくば
    • Year and Date
      2010-10-01
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 人体骨格筋におけるfast diffusion and slow diffusion component計測の試み2010

    • Author(s)
      岡本嘉一, 那須克宏, 磯辺智範, 只野喜一, 平野雄二, 南学
    • Organizer
      第38回日本磁気共鳴医学会大会
    • Place of Presentation
      つくば
    • Year and Date
      2010-10-01
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] Change of MR diffusion property during Active Muscle Contraction in the Calf2010

    • Author(s)
      Okamoto Y, Kunimatsu A, Kono T, NasuK, Niitsu M, Minami M
    • Organizer
      International society for magnetic resonance in medicine 18th scientific meeting and exhibition
    • Place of Presentation
      Stockholm, Sweden
    • Year and Date
      2010-05-05
    • Related Report
      2011 Final Research Report
  • [Presentation] Comparison of Diffusion Property Differences of the Calf Muscles between Athletes and Non-athletes2010

    • Author(s)
      Okamoto Y, Kunimatsu A, Mori S, Okamoto T, Inoguchi T, Minami M
    • Organizer
      International society for magnetic resonance in medicine 18th scientific meeting and exhibition
    • Place of Presentation
      Stockholm, Sweden
    • Year and Date
      2010-05-05
    • Related Report
      2011 Final Research Report
  • [Presentation] Comparison of Diffusion Property Differences of the Calf Muscles between Athletes and Non-athletes2010

    • Author(s)
      Yoshikazu Okamoto
    • Organizer
      International society for magnetic resonance in medicine 18^<th> scientific meeting and exhibition
    • Place of Presentation
      Stockholm(スウェーデン)
    • Year and Date
      2010-05-04
    • Related Report
      2010 Annual Research Report
  • [Presentation] Change of MR diffusion property during Active Muscle Contraction in the Calf2010

    • Author(s)
      Yoshikazu Okamoto
    • Organizer
      International society for magnetic resonance in medicine 18^<th> scientific meeting and exhibition
    • Place of Presentation
      Stockholm(スウェーデン)
    • Year and Date
      2010-05-04
    • Related Report
      2010 Annual Research Report
  • [Presentation] 骨格筋 fiber tractography の描出能に影響を与える要素の超音波とMRIを用いた検討2009

    • Author(s)
      岡本嘉一
    • Organizer
      第37回日本磁気共鳴医学会大会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-02
    • Related Report
      2009 Annual Research Report
  • [Presentation] 骨格筋fiber tractographyの描出能に影響を与える要素の超音波とMRIを用いた検討2009

    • Author(s)
      岡本嘉一, 鯨岡結賀, 南学
    • Organizer
      第37回日本磁気共鳴医学会大会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-01
    • Related Report
      2011 Final Research Report
  • [Presentation] Comparison of Diffusion Property Differences of the Calf Muscles between Athletes and Non-athletes2009

    • Author(s)
      岡本嘉一
    • Organizer
      The International Skeletal Society's 36th Annual Meeting
    • Place of Presentation
      Washington DC
    • Year and Date
      2009-09-04
    • Related Report
      2009 Annual Research Report
  • [Presentation] Comparison of Diffusion Property Differences of the Calf Muscles between Athletes and Non-athletes2009

    • Author(s)
      Okamoto Y, Kunimatsu A, Mori S, Okamoto T, Inoguchi T, Minami M
    • Organizer
      The International Skeletal Society's 36th Annual Meeting
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2009-09-03
    • Related Report
      2011 Final Research Report
  • [Presentation] Gender-specific differences in MR fiber tractography of skeletal muscles2009

    • Author(s)
      岡本嘉一
    • Organizer
      International society for magnetic resonance in medicine 17^<th> scientific meeting and exhibition
    • Place of Presentation
      Hawaii
    • Year and Date
      2009-04-23
    • Related Report
      2009 Annual Research Report
  • [Presentation] Gender-specific differences in MR fiber tractography of skeletal muscles2009

    • Author(s)
      Okamoto Y, Kunimatsu A, Kujiraoka Y, Inoguchi T, Okamoto T, Minami M
    • Organizer
      International society for magnetic resonance in medicine 17th scientific meeting and exhibition
    • Place of Presentation
      Hawaii, USA
    • Year and Date
      2009-04-20
    • Related Report
      2011 Final Research Report
  • [Presentation] 活動性筋収縮に伴う骨格筋拡散異方性変化の検討2009

    • Author(s)
      岡本嘉一, 國松聡, 河野達夫, 那須克宏, 新津守, 南学
    • Organizer
      第68回日本医学放射線学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-04-08
    • Related Report
      2011 Final Research Report 2009 Annual Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi