Development of similar image retrieval system for breast cancer diagnostic aid

• Project/Area Number: 21791179
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Radiation science
• Research Institution: Gifu University
• Principal Investigator: MURAMATSU Chisako 岐阜大学, 大学院・医学系研究科, 特定研究補佐員 (80509422)
• Project Period (FY): 2009 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥4,657,796 (Direct Cost: ¥3,582,920、Indirect Cost: ¥1,074,876); Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2011: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000); Fiscal Year 2010: ¥1,407,796 (Direct Cost: ¥1,082,920、Indirect Cost: ¥324,876); Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
• Keywords: 乳癌 / コンピュータ支援診断 / 画像処理 / 乳がん / 類似画像検索 / ディジタルマンモグラフィ / デジタルマンモグラフィ

Research Abstract

The purpose of this study was to develop a computer-aided diagnosis system that searches for similar already-diagnosed images as a reference. First, we have established a new digital mammography database and determined image features by computerized analysis. The gold standard of similarity for selecting reference images was obtained by experts. Using an artificial neural network and multidimensional scaling, we were able to determine similarity measures that correlate well with the gold standard. In the observer study, diagnostic accuracies were slightly improved by the presentation of similar images for both physician and radiological technologist groups.

Research Products

• [Journal Article] Representation of lesion similarity by use of multidimensional scaling for breast masses on mammograms. (2013)
  • Author(s): Muramatsu C, Nishimura K, Endo T, Oiwa M, Shiraiwa M, Doi K, Fujita H
  • Journal Title: J Digit Imaging Volume: (in press)
  • Peer Reviewed
• [Journal Article] Psychophysical similarity measure based on multi-dimesional scaling for retrieval of similar images of breast masses on mammograms (2013)
  • Author(s): Nishimura K, Muramatsu C, Oiwa M, Shiraiwa M, Endo T, Doi K, Fujita H
  • Journal Title: Proc SPIE Medical Imaging: Computer-Aided Diagnosis Volume: 8670
  • Peer Reviewed
• [Journal Article] Usefulness of presentation of similar images in the diagnosis of breast masses on mammograms: comparison of observer performances in Japan and the USA (2013)
  • Author(s): Muramatsu C, Schmidt RA, Shiraishi J, Endo T, Fujita H, Doi K
  • Journal Title: Radiol Phys Technol Volume: 6 Pages: 70-77
  • Peer Reviewed
• [Journal Article] Representation of lesion similarity by use of multidimensional scaling for breast masses on mammograms (2013)
  • Author(s): C.Muramatsu, K.Nishimura, T.Endo, M.Oiwa, M.Shiraiwa, K.Doi, and H.Fujita
  • Journal Title: Journal Digital Imaging Volume: 26 Issue: 4 Pages: 740-747
  • DOI: 10.1007/s10278-012-9569-0
  • Peer Reviewed
• [Journal Article] Psychophysical similarity measure based on multi-dimesional scaling for retrieval of similar images of breast masses on mammograms (2013)
  • Author(s): Nishimura K, Muramatsu C, Oiwa M, Shiraiwa M, Endo T, Doi K, Fujita H
  • Journal Title: Proc SPIE Medical Imaging Volume: in press
• [Journal Article] Shiraiwa M, Endo T, Doi K, Fujita H: Correspondence among subjective and objective similarities and pathologic types of breast masses on digital mammography. (2012)
  • Author(s): Muramatsu C, Nishimura K, Oiwa M, Shiraiwa M, Endo T, Doi K, Fujita H
  • Journal Title: WDM Springer Lectures Notes in Computer Science (LNCS) series Volume: 7361 Pages: 450-457
  • Peer Reviewed
• [Journal Article] Correspondence among subjective and objective similarities and pathologic types of breast masses on digital mammography (2012)
  • Author(s): Muramatsu C, Nishimura K, Oiwa M, Shiraiwa M, Endo T, Doi K, Fujita H
  • Journal Title: IWDM Springer Lectures Notes in Computer Science (LNCS) series Volume: 7361 Pages: 450-457
  • Peer Reviewed
• [Journal Article] コンピュータ支援画像診断技術の最先端 (2011)
  • Author(s): 藤田広志, 原武史, 周向栄, 福岡大輔, 村松千左子, 林達郎
  • Journal Title: 非破壊検査 Volume: 60巻 Pages: 686-693
  • NAID: 10030442191
• [Journal Article] Classifying breast masses in volumetric whole breast ultrasound data: a 2.5-dimensional approach. (2010)
  • Author(s): Lee GN, Okada T, Fukuoka D, Muramatsu C, Hara T, Morita T, Takada E, Endo T, Fujita H
  • Journal Title: Marti J, et al. (Eds.) IWDM Volume: 6036 Pages: 636-642
  • Peer Reviewed
• [Journal Article] Presentation of similar images as a reference for distinction between benign and malignant masses on mammograms: analysis of initial observer study (2010)
  • Author(s): Muramatsu C, Schmidt RA, Shiraishi J, Li Q, Doi K
  • Journal Title: J Digit Imaging Volume: 23(5) Pages: 592-602
  • Peer Reviewed
• [Journal Article] Presentation of similar images for diagnosis of breast masses on mammograms: analysis of the effect on residents. (2009)
  • Author(s): Muramatsu C, Schmidt RA, Shiraishi J, Li Q, Fujita H, Doi K
  • Journal Title: Proc SPIE Med Imaging Volume: 7260
• [Presentation] マンモグラムにおける腫瘤陰影の類似画像検索のための多次元尺度法に基づく心理物理的類似度の検討.医用画像情報学会(MII) (2013)
  • Author(s): 西村公平,村松千左子,大岩幹直,白岩美咲,遠藤登喜子,土井邦雄,藤田広志
  • Organizer: 平成24年度春季(第165回)大会
  • Place of Presentation: 北九州.口述発表
  • Year and Date: 2013-02-02
• [Presentation] Psychophysical similarity measure based on multi-dimesional scaling for retrieval of similar images of breast masses on mammograms (2013)
  • Author(s): Nishimura K, Muramatsu C, Oiwa M, Shiraiwa M, Endo T, Doi K, Fujita H
  • Organizer: SPIE Medical Imaging
  • Place of Presentation: Orlando, USA (poster)
• [Presentation] Psychophysical similarity measure based on multi-dimesional scaling for retrieval of similar images of breast masses on mammograms (2013)
  • Author(s): Nishimura K, Muramatsu C, Oiwa M, Shiraiwa M, Endo T, Doi K, Fujita H
  • Organizer: SPIE Medical Imaging
  • Place of Presentation: Orlando(USA)
• [Presentation] Feature-based modeling of a similarity map obtained by multidimensional scaling for diagnosis of breast masses on mammograms (2013)
  • Author(s): Muramatsu C, Nishimura K, Endo T, Oiwa M, Shiraiwa M, Doi K, Fujita H
  • Organizer: 日本放射線技術学会総会学術大会
  • Place of Presentation: パシフィコ横浜
• [Presentation] Determination of similarity measures using multidimensional scaling and linear regression models for selection of reference breast mass images. (2012)
  • Author(s): Muramatsu C, Nishimura K, Endo T, Oiwa M, Shiraiwa M, Doi K, Fujita H
  • Organizer: Oral Presentation at the RSNA Scientific Assembly and Annual Meeting
  • Place of Presentation: Chicago, USA
• [Presentation] Presentation of reference images and the pathological likelihood as a diagnostic aid for breast mass classification on mammograms (2012)
  • Author(s): Muramatsu C, Nishimura K, Endo T, Oiwa M, Shiraiwa M, Doi K, Fujita H
  • Organizer: Oral Presentation at Progress in Radiology 2012
  • Place of Presentation: Tokyo
• [Presentation] Correspondence among subjective and objective similarities and pathologic types of breast masses on digital mammography (2012)
  • Author(s): Muramatsu C, Nishimura K, Oiwa M, Shiraiwa M, Endo T, Doi K, Fujita H
  • Organizer: Poster presentation at the IWDM
  • Place of Presentation: Philadelphia, USA
• [Presentation] Correspondence among subjective and objective similarities and pathologic types of breast masses on digital mammography (2012)
  • Author(s): Muramatsu C, Nishimura K, Oiwa M, Shiraiwa M, Endo T, Doi K, Fujita H
  • Organizer: International Workshop on Breast Imaging
  • Place of Presentation: Philadelphia（USA)
• [Presentation] Presentation of reference images and the pathological likelihood as a diagnostic aid for breast mass classification on mammograms (2012)
  • Author(s): Muramatsu C, Nishimura K, Endo T, Oiwa M, Shiraiwa M, Doi K, Fujita H
  • Organizer: Progress in Radiology 2012
  • Place of Presentation: The Royal Norwegian Embassy(Tokyo)
• [Presentation] Determination of similarity measures using multidimensional scaling and linear regression models for selection of reference breast mass images (2012)
  • Author(s): Muramatsu C, Nishimura K, Endo T, Oiwa M, Shiraiwa M, Doi K, Fujita H
  • Organizer: RSNA Scientific Assembly and Annual Meeting
  • Place of Presentation: Chicago(USA)
• [Presentation] Determination of similarity measures by using subjective ratings and pathological likelihood (2011)
  • Author(s): 村松千左子, 西村公平, 大岩幹直, 白岩美咲, 遠藤登喜子, 土井邦雄, 藤田広志
  • Organizer: Radiological Society of North America (RSNA) Annual Meeting
  • Place of Presentation: Chicago, USA
  • Year and Date: 2011-11-28
• [Presentation] 心理物理的類似度によるディジタルマンモグラムにおける腫瘤陰影の類似画像検索 (2011)
  • Author(s): 西村公平, 村松千左子, 原武史, 藤田広志
  • Organizer: 日本医用画像工学会大会(JAMIT)
  • Place of Presentation: 国際医療福祉大学
  • Year and Date: 2011-08-06
• [Presentation] Determination of similarity measures by using subjective ratings and pathological likelihood (2011)
  • Author(s): Muramatsu C, Nishimura K, Ooiwa M, Shiraiwa M, Endo T, Doi K, Fujita H
  • Organizer: Poster Presentation at the RSNA Scientific Assembly and Annual Meeting
  • Place of Presentation: Chicago, USA
• [Presentation] 心理物理的類似度によるディジタルマンモグラムにおける腫瘤陰影の類似画像検索 (2011)
  • Author(s): 西村 公平,村松 千左子,原 武史,藤田 広志
  • Organizer: 日本医用画像工学会(JAMIT)大会
  • Place of Presentation: 福祉大学
• [Presentation] Classification of breast lesions by use of a reference database with similarity index (2010)
  • Author(s): Muramatsu C, Endo T, Doi K, Nishimura K, Ooiwa M, Shiraiwa M, Fujita H
  • Organizer: Education Exhibit Presentation at the RSNA Scientific Assembly and Annual Meeting
  • Place of Presentation: Chicago, USA
• [Presentation] Classification of breast lesions by use of a reference database with similarity index (2010)
  • Author(s): 村松千左子, 遠藤登喜子, 土井邦雄, 西村公平, 大岩幹直, 白岩美咲, 藤田廣志
  • Organizer: Radiological Society of North America (RSNA) Annual Meeting
  • Place of Presentation: Chicago, USA
• [Presentation] 物理評価値と主観的評価値(ROC,2AFC)の関係, 画像について語ろう, テーマ「ディジタル画像の総合的画質評価」 (2009)
  • Author(s): 村松千左子
  • Organizer: 第37回日本放射線技術学会秋季学術大会 第66回画像分科会
  • Place of Presentation: 岡山コンベンションセンター
  • Year and Date: 2009-10-24
• [Presentation] マンモグラムにおける類似画像を利用した腫瘤の良悪性鑑別:日米のExpertsとNon-expertsによる読影実験結果(Distinction between benign and malignant masses on mammograms by use of similar images: Comparison of the observer study results by experts and non-experts in Japan and the US)口述発表 (2009)
  • Author(s): 村松千左子,白石順二, 遠藤登喜子,藤田廣志,土井邦雄
  • Organizer: 医用画像情報学会平成21年度年次(第154回)大会
  • Place of Presentation: 金沢
  • Year and Date: 2009-06-06
• [Presentation] マモグラム上の腫瘤陰影の鑑別診断における日米での読影実験結果の比較(Usefulness of the presentation of similar images: Comparison of the observer study results in Japan and the US for diagnosis of breast masses on mammograms)電子ポスタ(CyPos) (2009)
  • Author(s): 村松千左子,Schmidt RA,白石順二,遠藤登喜子,藤田廣志,土井邦雄
  • Organizer: 第65回日本放射線技術学会総会学術大会
  • Place of Presentation: 横浜
• [Book] 第6章2節2項2目 類似画像検索による乳房画像における腫瘤の良悪性鑑別.監修:藤田広志,石田隆行,桂川茂彦.実践 医用画像解析ハンドブック (2012)
  • Author(s): 村松千左子
  • Publisher: オーム社
• [Book] 実践 医用画像解析ハンドブック (2012)
  • Author(s): 村松千左子（分担執筆）
  • Total Pages: 6
  • Publisher: オーム社
• [Book] 第2編第6章6節 類似画像のCAD.監修:石田隆行,桂川茂彦,藤田廣志.医用画像ハンドブック (2010)
  • Author(s): 村松千左子
  • Publisher: オーム社