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Real-time monitoring of urethral dose and prediction of urethral complication for prostate brachytherapy

Research Project

Project/Area Number 21791212
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Radiation science
Research InstitutionKeio University

Principal Investigator

OHASHI Toshio  Keio University, 医学部, 講師 (70327641)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords前立腺癌 / 小線源治療 / 尿道線量 / 線量測定
Research Abstract

It is important for predicting the late morbidity of urethra to evaluate the urethral dose correctly at prostate seed implantation. The difference was seen by the method of the dose calculation in the dose volume histogram. Especially, the difference of 5% on the average was seen in the low to moderate dose area as for the urethra dose. It was thought that the grasp of an accurate urethra dose to evaluate the validity of the measurement became possible.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (30 results)

All 2011 2010 2009 Other

All Journal Article (3 results) (of which Peer Reviewed: 2 results) Presentation (24 results) Book (2 results) Remarks (1 results)

  • [Journal Article] Evaluation of the dosimetric parameters for 125I brachytherapy determined in prostate medium using CT images.2010

    • Author(s)
      Takashi Hanada, Atsunori Yorozu, Toshio Ohashi, Naoyuki Shigematsu, Koichi Maruyama.
    • Journal Title

      J Radiat Res 51

      Pages: 553-561

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 前立腺癌シード療法の知識2009

    • Author(s)
      大橋俊夫
    • Journal Title

      画像診断 29

      Pages: 1394-1401

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Dose Constraint for Minimizing Grade 2+ Rectal Bleeding following Brachytherapy combined with External Beam Radiotherapy for Localized Prostate Cancer : Rectal Dose-Volume Histogram Analysis of 457 Patients.

    • Author(s)
      Yutaka Shiraishi, Atsunori Yorozu, Toshio Ohashi, Kazuhito Toya, Satoshi Seki, Kayo Yoshida, Tomoya Kaneda, Shiro Saito, Toru Nishiyama, Takashi Hanada, Naoyuki Shigematsu.
    • Journal Title

      Int J Radiat Oncol Biol Phys in print

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Presentation] Vs.IMRT2011

    • Author(s)
      大橋俊夫
    • Organizer
      第4回千葉ブラキテラピーフォーラム
    • Place of Presentation
      千葉
    • Year and Date
      2011-03-09
    • Related Report
      2010 Final Research Report
  • [Presentation] Vs.IMRT2011

    • Author(s)
      大橋俊夫
    • Organizer
      千葉ブラキセラピーフォーラム
    • Place of Presentation
      千葉
    • Year and Date
      2011-03-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] MRI-based Postimplant Dosimetric Assessment for Permanent Prostate Brachytherapy.2010

    • Author(s)
      大橋俊夫, 門間哲雄, 山下昌次, 花田剛士, 深田淳一, 茂松直之
    • Organizer
      第23回日本放射線腫瘍学会学術大会
    • Place of Presentation
      千葉
    • Year and Date
      2010-11-20
    • Related Report
      2010 Final Research Report
  • [Presentation] 食道癌におけるInterfraction Esophageal Motionの検討2010

    • Author(s)
      深田淳一, 茂松直之, 大橋俊夫, 花田剛士, 竹内裕也, 北川雄光
    • Organizer
      第23回日本放射線腫瘍学会学術大会
    • Place of Presentation
      千葉
    • Year and Date
      2010-11-20
    • Related Report
      2010 Final Research Report
  • [Presentation] I-125シード治療におけるBED増加に伴う有害事象の検討2010

    • Author(s)
      江里口貴久, 大橋俊夫, 門間哲雄, 山下昌次, 茂松直之
    • Organizer
      第23回日本放射線腫瘍学会学術大会
    • Place of Presentation
      千葉
    • Year and Date
      2010-11-20
    • Related Report
      2010 Final Research Report
  • [Presentation] 限局性NSCLCに対するSBRTにて、SUVmaxはT因子を上回る有意な局所再発の危険因子である2010

    • Author(s)
      武田篤也, 横須賀典子, 大橋俊夫, 国枝悦夫, 青木陽介, 藤井博史, 茂松直之
    • Organizer
      第23回日本放射線腫瘍学会学術大会
    • Place of Presentation
      千葉
    • Year and Date
      2010-11-18
    • Related Report
      2010 Final Research Report
  • [Presentation] 前立腺癌中間リスク群に対する術前内分泌療法はPSA再発を減らせるか?2010

    • Author(s)
      萬篤憲, 戸矢和仁, 白石悠, 吉田佳代, 金田朋也, 斉藤史郎, 大橋俊夫
    • Organizer
      第23回日本放射線腫瘍学会学術大会
    • Place of Presentation
      千葉
    • Year and Date
      2010-11-18
    • Related Report
      2010 Final Research Report
  • [Presentation] Impact on MRI-based Postimplant Dosimetric Assessment for Permanent Prostate Brachytherapy using Contrast-enhanced T1 Weighted Images.2010

    • Author(s)
      Toshio Ohashi, Tetsuo Momma, Shoji Yamashita, Takashi Hanada, Junichi Fukada, Yutaka Shiraishi, Naoyuki Shigematsu.
    • Organizer
      The 52nd American Society for Therapeutic Radiology and Oncology Annual Meeting.
    • Place of Presentation
      サンディエゴ、アメリカ
    • Year and Date
      2010-11-02
    • Related Report
      2010 Final Research Report
  • [Presentation] Interfraction Esophageal Motion in Patients Receiving Radiotherapy for Esophageal Cancer.2010

    • Author(s)
      Junichi Fukada, Naoyuki Shigematsu, Toshio Ohashi, Takashi Hanada, Hiroya Takeuchi, Shimpei Hashimoto, Yuko Kitagawa.
    • Organizer
      The 52nd American Society for Therapeutic Radiology and Oncology Annual Meeting.
    • Place of Presentation
      サンディエゴ、アメリカ
    • Year and Date
      2010-11-02
    • Related Report
      2010 Final Research Report
  • [Presentation] MRI-based Postimplant Dosimetric Assessment for Permanent Prostate Brachytherapy2010

    • Author(s)
      大橋俊夫
    • Organizer
      American Society for Therapeutic Radiology and Oncology Annual Meeting
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2010-11-02
    • Related Report
      2010 Annual Research Report
  • [Presentation] 早期前立腺癌のシード療法:複数の中間リスク因子は高リスクに相当するか2010

    • Author(s)
      萬篤憲, 白石悠, 戸矢和仁, 吉田佳代, 金田朋也, 斉藤史郎, 西山徹, 大橋俊夫
    • Organizer
      第48回日本癌治療学会総会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2010-10-30
    • Related Report
      2010 Final Research Report
  • [Presentation] 術前・術中プランニング2010

    • Author(s)
      大橋俊夫
    • Organizer
      第12回ヨウ素125シード線源永久挿入による前立腺癌密封小線源療法技術講習会
    • Place of Presentation
      東京
    • Year and Date
      2010-06-12
    • Related Report
      2010 Final Research Report
  • [Presentation] アドバンスト&リフレッシャーコース・前立腺世界の潮流IMRT vsBrachytherapy2010

    • Author(s)
      大橋俊夫
    • Organizer
      第12回日本放射線腫瘍学会小線源治療部会
    • Place of Presentation
      東京
    • Year and Date
      2010-05-16
    • Related Report
      2010 Final Research Report
  • [Presentation] 前立腺世界の潮流IMRT vs Brachytherapy2010

    • Author(s)
      大橋俊夫
    • Organizer
      日本放射線腫瘍学会小線源治療部会
    • Place of Presentation
      東京
    • Year and Date
      2010-05-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] Defining the Dose Constraint of Developing Grade 2 Proctitis following 125I Prostate Brachytherapy Combined with External Beam Using a Rectal Dose-Volume Histogram Analysis.2010

    • Author(s)
      Atsunori Yorozu, Yutaka Shiraishi, Kazuhito Toya, Satoshi Seki, Tomoya Kaneda, Shiro Saito, Toru Nishiyama, Toshio Ohashi.
    • Organizer
      The 31st Annual Meeting of the American Brachytherapy Society.
    • Place of Presentation
      アトランタ、アメリカ
    • Year and Date
      2010-05-01
    • Related Report
      2010 Final Research Report
  • [Presentation] I-125小線源治療におけるBED増加に伴う有害事象に関する検討2010

    • Author(s)
      門間哲雄、海老根崇、長妻克己、大橋俊夫、山下昌次
    • Organizer
      第98回日本泌尿器科学会総会
    • Place of Presentation
      盛岡
    • Year and Date
      2010-04-28
    • Related Report
      2010 Final Research Report
  • [Presentation] 外照射併用シード療法に於けるGrade2直腸炎と外照射DVHの検討2010

    • Author(s)
      白石悠, 萬篤憲, 大橋俊夫, 戸矢和仁, 関智史, 金田朋也, 西山徹, 斉藤史郎
    • Organizer
      第69回日本医学放射線学会総会・学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2010-04-10
    • Related Report
      2010 Final Research Report
  • [Presentation] 自動輪郭認識機能(ABAS)の有用性-全脳での検討-2010

    • Author(s)
      楊井祥典, 深田淳一, 堤啓, 奥洋平, 西郷拓也, 香坂浩之, 川口修, 大橋俊夫, 茂松直之
    • Organizer
      第69回日本医学放射線学会総会・学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2010-04-10
    • Related Report
      2010 Final Research Report
  • [Presentation] 自動輪郭認識機能の有用性 -肝臓での検討-2010

    • Author(s)
      堤啓, 深田淳一, 楊井祥典, 奥洋平, 西郷拓也, 香坂浩之, 川口修, 大橋俊夫, 茂松直之
    • Organizer
      第69回日本医学放射線学会総会・学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2010-04-10
    • Related Report
      2010 Final Research Report
  • [Presentation] HCCに対する体幹部定位放射線治療(SBRT)後に生じる周囲正常肝反応のDVH2010

    • Author(s)
      武田篤也、大橋俊夫
    • Organizer
      第21回日本高精度放射線外部照射研究会
    • Place of Presentation
      熊本
    • Year and Date
      2010-01-30
    • Related Report
      2009 Annual Research Report
  • [Presentation] 前立腺癌シード治療の有害事象シード単独療法vs外照射併用療法2009

    • Author(s)
      大橋俊夫
    • Organizer
      第47回日本癌治療学会総会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] 前立腺癌に対する外照射併用I-125シード治療の有害事象2009

    • Author(s)
      大橋俊夫
    • Organizer
      第22回日本放射線腫瘍学会学術大会
    • Place of Presentation
      京都
    • Year and Date
      2009-09-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] I-125シード治療におけるBEDと早期排尿症状に関する検討2009

    • Author(s)
      大橋俊夫
    • Organizer
      第6回前立腺癌密封小線源永久挿入治療研究会
    • Place of Presentation
      東京
    • Year and Date
      2009-07-19
    • Related Report
      2009 Annual Research Report
  • [Presentation] 前立腺癌における外照射併用シード治療の有害事象の検討2009

    • Author(s)
      大橋俊夫
    • Organizer
      第11回日本放射線腫瘍学会小線源治療部会
    • Place of Presentation
      札幌
    • Year and Date
      2009-06-13
    • Related Report
      2009 Annual Research Report
  • [Book] 前立腺癌シード療法における術中計画法(リアルタイムによる辺縁配置法&EBRT併用療法ガイドブック)2010

    • Author(s)
      大橋俊夫, 他
    • Publisher
      日本メジフィジックス株式会社
    • Related Report
      2010 Final Research Report
  • [Book] リアルタイムによる辺縁配置法&EBRT併用療法 ガイドブック2010

    • Author(s)
      大橋俊夫
    • Total Pages
      11
    • Publisher
      日本メジフィジックス株式会社
    • Related Report
      2010 Annual Research Report
  • [Remarks] ホームページ等 なし

    • Related Report
      2010 Final Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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