Cryoablation for lung tumors : optimal freeze-thaw sequence and clinical application
| Project/Area Number |
21791214
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Radiation science
|
|---|
| Research Institution | Keio University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2009 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
|---|
| Keywords | インターベンショナルラジオロジー(IVR) / 凍結治療 / 肺腫瘍 / IVR / 放射線科学 / 癌 / インターベンショナルラジオロジー |
|---|
| Research Abstract |
1) We drew the isothermal curves by measuring the temperature of a normal porcine lung in vivo based on the same freeze-thaw cycles as actual cryoablation for malignant lung tumors. As a result of the analysis with the isothermal curve and the freezing function, the frozen area of the iceball was larger in the second cycle than in the first cycle. It is supposed that bleeding in the first freeze-thaw cycle increases the thermal diffusivity around the cryoprobe and it is enabled to freeze a greater area in the second freezing. 2) The correlation between the isothermal curves and histologic findings was examined. These findings were also compared with the clinical findings on computed tomography(CT). The present study has demonstrated that the less than-20℃zone corresponds to the central solid zone on CT.
|
Report
(4 results)
Research Products
(15 results)
-
-
-
-
-
-
-
-
-
-
-
[Presentation] 凍結治療の現状と未来2011
Author(s)
井上政則
Organizer
第13回放射線科IVRセミナー
Place of Presentation
大阪大学医学部臨床研究棟(大阪府)(招待講演)
Year and Date
2011-12-09
Related Report
-
-
-
-
