| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
|---|
| Research Abstract |
The implantation of autologous bone marrow cells did not improve clinical symptoms or regional perfusion of ischemia in some patients. It speculates that this poor angiogenic potency is related to the complications of diabetes mellitus. However, the precise mechanisms of diabetes-related impairment of bone marrow cells are not fully understood. This study shows that oxidative stress contributes to the diabetes-related functional impairment of bone marrow cells, which can be attenuated by antioxidant therapy.
|
